| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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121 genes differentially expressed following the BRD-A19500257_geldanamycin_MCF7_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 |
| ACKR3 | atypical chemokine receptor 3 |
| AMOTL2 | angiomotin like 2 |
| ARHGAP29 | Rho GTPase activating protein 29 |
| BPIFA1 | BPI fold containing family A, member 1 |
| CAB39 | calcium binding protein 39 |
| CFB | complement factor B |
| CRYZ | crystallin, zeta (quinone reductase) |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DPYD | dihydropyrimidine dehydrogenase |
| DUSP1 | dual specificity phosphatase 1 |
| ECM1 | extracellular matrix protein 1 |
| FOLR1 | folate receptor 1 (adult) |
| FXR1 | fragile X mental retardation, autosomal homolog 1 |
| GUSBP11 | glucuronidase, beta pseudogene 11 |
| H2AFV | H2A histone family, member V |
| HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 |
| HSPA1A | heat shock 70kDa protein 1A |
| IFITM2 | interferon induced transmembrane protein 2 |
| IGHD | immunoglobulin heavy constant delta |
| IGHM | immunoglobulin heavy constant mu |
| IGKC | immunoglobulin kappa constant |
| IGKV1-5 | immunoglobulin kappa variable 1-5 |
| IGKV4-1 | immunoglobulin kappa variable 4-1 |
| IGL | immunoglobulin lambda locus |
| IGLJ3 | immunoglobulin lambda joining 3 |
| IGLL3P | immunoglobulin lambda-like polypeptide 3, pseudogene |
| IGLV2-23 | immunoglobulin lambda variable 2-23 |
| JCHAIN | joining chain of multimeric IgA and IgM |
| KRT18 | keratin 18, type I |
| LCN2 | lipocalin 2 |
| LDOC1 | leucine zipper, down-regulated in cancer 1 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein |
| LIMCH1 | LIM and calponin homology domains 1 |
| LOXL2 | lysyl oxidase-like 2 |
| LTB | lymphotoxin beta (TNF superfamily, member 3) |
| LUM | lumican |
| MAP2K5 | mitogen-activated protein kinase kinase 5 |
| NEBL | nebulette |
| NPTX2 | neuronal pentraxin II |
| PAN2 | PAN2 poly(A) specific ribonuclease subunit |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 |
| PEG10 | paternally expressed 10 |
| PFN2 | profilin 2 |
| PGM1 | phosphoglucomutase 1 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
| PRUNE2 | prune homolog 2 (Drosophila) |
| QPRT | quinolinate phosphoribosyltransferase |
| REEP1 | receptor accessory protein 1 |
| RFX5 | regulatory factor X, 5 (influences HLA class II expression) |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) |
| SCGB1A1 | secretoglobin, family 1A, member 1 (uteroglobin) |
| SLPI | secretory leukocyte peptidase inhibitor |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing |
| TCFL5 | transcription factor-like 5 (basic helix-loop-helix) |
| TMEM45A | transmembrane protein 45A |
| WSB1 | WD repeat and SOCS box containing 1 |
| Symbol | Name |
|---|---|
| ANOS1 | anosmin 1 |
| APOD | apolipoprotein D |
| AREG | amphiregulin |
| BHLHE41 | basic helix-loop-helix family, member e41 |
| CCNE2 | cyclin E2 |
| CDC25A | cell division cycle 25A |
| CDC6 | cell division cycle 6 |
| CENPU | centromere protein U |
| CXCL14 | chemokine (C-X-C motif) ligand 14 |
| DTL | denticleless E3 ubiquitin protein ligase homolog (Drosophila) |
| EGR3 | early growth response 3 |
| EIF5 | eukaryotic translation initiation factor 5 |
| ENDOD1 | endonuclease domain containing 1 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 |
| EREG | epiregulin |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) |
| FABP7 | fatty acid binding protein 7, brain |
| FEN1 | flap structure-specific endonuclease 1 |
| FGFR3 | fibroblast growth factor receptor 3 |
| FKBP14 | FK506 binding protein 14, 22 kDa |
| FYN | FYN proto-oncogene, Src family tyrosine kinase |
| GDF15 | growth differentiation factor 15 |
| GINS2 | GINS complex subunit 2 (Psf2 homolog) |
| GJA1 | gap junction protein, alpha 1, 43kDa |
| GLUL | glutamate-ammonia ligase |
| GNAI1 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 |
| GRIA2 | glutamate receptor, ionotropic, AMPA 2 |
| HBB | hemoglobin, beta |
| INHBA | inhibin, beta A |
| JAG1 | jagged 1 |
| KRT14 | keratin 14, type I |
| KRT17 | keratin 17, type I |
| KRT6A | keratin 6A, type II |
| LOXL1 | lysyl oxidase-like 1 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 |
| MDK | midkine (neurite growth-promoting factor 2) |
| MELK | maternal embryonic leucine zipper kinase |
| NDNF | neuron-derived neurotrophic factor |
| NID2 | nidogen 2 (osteonidogen) |
| NPY1R | neuropeptide Y receptor Y1 |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 |
| PDE4B | phosphodiesterase 4B, cAMP-specific |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 |
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit |
| PTX3 | pentraxin 3, long |
| SCYL3 | SCY1-like 3 (S. cerevisiae) |
| SEMA6A | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 |
| SLC1A1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 |
| SPP1 | secreted phosphoprotein 1 |
| SULT1C2 | sulfotransferase family, cytosolic, 1C, member 2 |
| SYNGR3 | synaptogyrin 3 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 |
| TLR4 | toll-like receptor 4 |
| TM4SF1 | transmembrane 4 L six family member 1 |
| TMEM47 | transmembrane protein 47 |
| TUBB2A | tubulin, beta 2A class IIa |
| WARS | tryptophanyl-tRNA synthetase |
| WSB2 | WD repeat and SOCS box containing 2 |
