BRD-A21584801_brivanib_BT20_3_h_0.04_um Gene Set
Genes
32 genes differentially expressed following the BRD-A21584801_brivanib_BT20_3_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
increased expression
Symbol |
Name |
ABCA1
|
ATP-binding cassette, sub-family A (ABC1), member 1
|
CPE
|
carboxypeptidase E
|
DAPK1
|
death-associated protein kinase 1
|
EFNB2
|
ephrin-B2
|
FOLR1
|
folate receptor 1 (adult)
|
GLG1
|
golgi glycoprotein 1
|
KCTD12
|
potassium channel tetramerization domain containing 12
|
MYO6
|
myosin VI
|
PDLIM5
|
PDZ and LIM domain 5
|
SCG2
|
secretogranin II
|
SORL1
|
sortilin-related receptor, L(DLR class) A repeats containing
|
SOX9
|
SRY (sex determining region Y)-box 9
|
STC2
|
stanniocalcin 2
|
VCAN
|
versican
|
decreased expression
Symbol |
Name |
CD44
|
CD44 molecule (Indian blood group)
|
CXCL8
|
chemokine (C-X-C motif) ligand 8
|
FGFR3
|
fibroblast growth factor receptor 3
|
G0S2
|
G0/G1 switch 2
|
GDF15
|
growth differentiation factor 15
|
GGH
|
gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase)
|
LEF1
|
lymphoid enhancer-binding factor 1
|
NPEPL1
|
aminopeptidase-like 1
|
PLA2G2A
|
phospholipase A2, group IIA (platelets, synovial fluid)
|
RHOBTB3
|
Rho-related BTB domain containing 3
|
RNF128
|
ring finger protein 128, E3 ubiquitin protein ligase
|
S100A8
|
S100 calcium binding protein A8
|
SERPINE2
|
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
|
SNCA
|
synuclein, alpha (non A4 component of amyloid precursor)
|
SORD
|
sorbitol dehydrogenase
|
SPON2
|
spondin 2, extracellular matrix protein
|
TRIB2
|
tribbles pseudokinase 2
|
ZBTB20
|
zinc finger and BTB domain containing 20
|