| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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148 genes differentially expressed following the BRD-A22783572_-666_MCF7_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 |
| ACSL1 | acyl-CoA synthetase long-chain family member 1 |
| ANXA1 | annexin A1 |
| ANXA3 | annexin A3 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) |
| ATF3 | activating transcription factor 3 |
| C9ORF3 | chromosome 9 open reading frame 3 |
| CAPN2 | calpain 2, (m/II) large subunit |
| CAV1 | caveolin 1, caveolae protein, 22kDa |
| CAV2 | caveolin 2 |
| CDC42BPB | CDC42 binding protein kinase beta (DMPK-like) |
| CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CLC | Charcot-Leyden crystal galectin |
| CLIC4 | chloride intracellular channel 4 |
| CTGF | connective tissue growth factor |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 |
| DAXX | death-domain associated protein |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DEFA4 | defensin, alpha 4, corticostatin |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 |
| DLGAP4 | discs, large (Drosophila) homolog-associated protein 4 |
| DPYSL3 | dihydropyrimidinase-like 3 |
| DUSP4 | dual specificity phosphatase 4 |
| EGR1 | early growth response 1 |
| ELANE | elastase, neutrophil expressed |
| EPHA2 | EPH receptor A2 |
| EREG | epiregulin |
| F13A1 | coagulation factor XIII, A1 polypeptide |
| FLNA | filamin A, alpha |
| GABRE | gamma-aminobutyric acid (GABA) A receptor, epsilon |
| GADD45A | growth arrest and DNA-damage-inducible, alpha |
| GARS | glycyl-tRNA synthetase |
| GRB10 | growth factor receptor-bound protein 10 |
| HIST1H2BG | histone cluster 1, H2bg |
| HMOX1 | heme oxygenase 1 |
| IFRD1 | interferon-related developmental regulator 1 |
| INHBB | inhibin, beta B |
| JAG1 | jagged 1 |
| KLF6 | Kruppel-like factor 6 |
| KLK10 | kallikrein-related peptidase 10 |
| LAMB3 | laminin, beta 3 |
| LAMC2 | laminin, gamma 2 |
| LCN2 | lipocalin 2 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 |
| MAGEA3 | melanoma antigen family A3 |
| MAP1B | microtubule-associated protein 1B |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta |
| MBTPS1 | membrane-bound transcription factor peptidase, site 1 |
| MS4A3 | membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) |
| NNMT | nicotinamide N-methyltransferase |
| NPTX2 | neuronal pentraxin II |
| NT5E | 5'-nucleotidase, ecto (CD73) |
| OSBPL3 | oxysterol binding protein-like 3 |
| PSAT1 | phosphoserine aminotransferase 1 |
| PTPRE | protein tyrosine phosphatase, receptor type, E |
| PTX3 | pentraxin 3, long |
| RAP1GAP | RAP1 GTPase activating protein |
| RNF19B | ring finger protein 19B |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 |
| RTN2 | reticulon 2 |
| S100A12 | S100 calcium binding protein A12 |
| S100A9 | S100 calcium binding protein A9 |
| S100P | S100 calcium binding protein P |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SMAD3 | SMAD family member 3 |
| STAR | steroidogenic acute regulatory protein |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) |
| TGFA | transforming growth factor, alpha |
| TGFBI | transforming growth factor, beta-induced, 68kDa |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 |
| TPM1 | tropomyosin 1 (alpha) |
| TUBB2A | tubulin, beta 2A class IIa |
| VAT1 | vesicle amine transport 1 |
| VEGFA | vascular endothelial growth factor A |
| ZYX | zyxin |
| Symbol | Name |
|---|---|
| ABLIM1 | actin binding LIM protein 1 |
| AKR7A2 | aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) |
| ALG8 | ALG8, alpha-1,3-glucosyltransferase |
| ARMT1 | acidic residue methyltransferase 1 |
| B3GNT1 | |
| C14ORF1 | chromosome 14 open reading frame 1 |
| C1S | complement component 1, s subcomponent |
| C2CD5 | C2 calcium-dependent domain containing 5 |
| C3 | complement component 3 |
| CCND1 | cyclin D1 |
| CDCA4 | cell division cycle associated 4 |
| CDK1 | cyclin-dependent kinase 1 |
| CFB | complement factor B |
| CHEK2 | checkpoint kinase 2 |
| CYB5A | cytochrome b5 type A (microsomal) |
| DCXR | dicarbonyl/L-xylulose reductase |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 |
| DTL | denticleless E3 ubiquitin protein ligase homolog (Drosophila) |
| EED | embryonic ectoderm development |
| ESR1 | estrogen receptor 1 |
| FAM63A | family with sequence similarity 63, member A |
| FEN1 | flap structure-specific endonuclease 1 |
| GATA3 | GATA binding protein 3 |
| GINS1 | GINS complex subunit 1 (Psf1 homolog) |
| GPC3 | glypican 3 |
| GSTM3 | glutathione S-transferase mu 3 (brain) |
| HEBP1 | heme binding protein 1 |
| HES1 | hes family bHLH transcription factor 1 |
| HILPDA | hypoxia inducible lipid droplet-associated |
| HIST1H4C | histone cluster 1, H4c |
| HLF | hepatic leukemia factor |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein |
| IFITM1 | interferon induced transmembrane protein 1 |
| IGL | immunoglobulin lambda locus |
| IMP3 | IMP3, U3 small nucleolar ribonucleoprotein |
| ISOC1 | isochorismatase domain containing 1 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein |
| LRIG1 | leucine-rich repeats and immunoglobulin-like domains 1 |
| MCM2 | minichromosome maintenance complex component 2 |
| MGP | matrix Gla protein |
| NCK1 | NCK adaptor protein 1 |
| NET1 | neuroepithelial cell transforming 1 |
| NME4 | NME/NM23 nucleoside diphosphate kinase 4 |
| PCNA | proliferating cell nuclear antigen |
| PRKCD | protein kinase C, delta |
| QDPR | quinoid dihydropteridine reductase |
| RAB31 | RAB31, member RAS oncogene family |
| RAD51AP1 | RAD51 associated protein 1 |
| RFC2 | replication factor C (activator 1) 2, 40kDa |
| RFC5 | replication factor C (activator 1) 5, 36.5kDa |
| RNASE4 | ribonuclease, RNase A family, 4 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 |
| SLC29A1 | solute carrier family 29 (equilibrative nucleoside transporter), member 1 |
| SMC2 | structural maintenance of chromosomes 2 |
| SNRNP25 | small nuclear ribonucleoprotein 25kDa (U11/U12) |
| SRSF1 | serine/arginine-rich splicing factor 1 |
| SRSF7 | serine/arginine-rich splicing factor 7 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa |
| SUB1 | SUB1 homolog (S. cerevisiae) |
| TFF3 | trefoil factor 3 (intestinal) |
| TFPI2 | tissue factor pathway inhibitor 2 |
| TMEM109 | transmembrane protein 109 |
| TOMM70A | translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae) |
| TOP2A | topoisomerase (DNA) II alpha 170kDa |
| TOPBP1 | topoisomerase (DNA) II binding protein 1 |
| UBE2A | ubiquitin-conjugating enzyme E2A |
| UBE2C | ubiquitin-conjugating enzyme E2C |
| UBR7 | ubiquitin protein ligase E3 component n-recognin 7 (putative) |
| UCP2 | uncoupling protein 2 (mitochondrial, proton carrier) |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) |
