BRD-A24054354_-666_HEPG2_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

69 genes differentially expressed following the BRD-A24054354_-666_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADRB2 adrenoceptor beta 2, surface
AK4 adenylate kinase 4
ALDOA aldolase A, fructose-bisphosphate
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
BTG2 BTG family, member 2
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
COMP cartilage oligomeric matrix protein
CRABP2 cellular retinoic acid binding protein 2
CXCL8 chemokine (C-X-C motif) ligand 8
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EIF5 eukaryotic translation initiation factor 5
FST follistatin
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase)
GLUL glutamate-ammonia ligase
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
HBB hemoglobin, beta
HCAR3 hydroxycarboxylic acid receptor 3
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
HSPA6 heat shock 70kDa protein 6 (HSP70B')
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains)
LPAR1 lysophosphatidic acid receptor 1
MT1F metallothionein 1F
MT1G metallothionein 1G
MT1HL1 metallothionein 1H-like 1
MT1X metallothionein 1X
MXI1 MAX interactor 1, dimerization protein
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
PAN2 PAN2 poly(A) specific ribonuclease subunit
PEG3 paternally expressed 3
RGCC regulator of cell cycle
S100A14 S100 calcium binding protein A14
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SFTPA2 surfactant protein A2
SLC39A8 solute carrier family 39 (zinc transporter), member 8
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SPAG4 sperm associated antigen 4
SQSTM1 sequestosome 1
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
TSPAN8 tetraspanin 8
TXNRD1 thioredoxin reductase 1
ZBTB18 zinc finger and BTB domain containing 18

decreased expression

Symbol Name
BCHE butyrylcholinesterase
CAPG capping protein (actin filament), gelsolin-like
CCL5 chemokine (C-C motif) ligand 5
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CHMP4A charged multivesicular body protein 4A
CRYAB crystallin, alpha B
CXCL9 chemokine (C-X-C motif) ligand 9
DENND2D DENN/MADD domain containing 2D
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6
FADS1 fatty acid desaturase 1
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial
KRT81 keratin 81, type II
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
MXRA5 matrix-remodelling associated 5
NTS neurotensin
PLA2G16 phospholipase A2, group XVI
POSTN periostin, osteoblast specific factor
RGS1 regulator of G-protein signaling 1
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SESN1 sestrin 1
TRAPPC3 trafficking protein particle complex 3
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