BRD-A28318179_-666_HEPG2_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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53 genes differentially expressed following the BRD-A28318179_-666_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AMIGO2 adhesion molecule with Ig-like domain 2
ANPEP alanyl (membrane) aminopeptidase
APOLD1 apolipoprotein L domain containing 1
ASPH aspartate beta-hydroxylase
BANK1 B-cell scaffold protein with ankyrin repeats 1
CAST calpastatin
CD44 CD44 molecule (Indian blood group)
CHMP4A charged multivesicular body protein 4A
CLC Charcot-Leyden crystal galectin
CSTA cystatin A (stefin A)
DENND2D DENN/MADD domain containing 2D
FOXF2 forkhead box F2
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
GPM6A glycoprotein M6A
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
HOXB2 homeobox B2
IDO1 indoleamine 2,3-dioxygenase 1
IGL immunoglobulin lambda locus
KRT18 keratin 18, type I
KRT7 keratin 7, type II
LMO3 LIM domain only 3 (rhombotin-like 2)
MAGEA3 melanoma antigen family A3
MANSC1 MANSC domain containing 1
MMP1 matrix metallopeptidase 1
MT1X metallothionein 1X
NTS neurotensin
PERP PERP, TP53 apoptosis effector
PLP2 proteolipid protein 2 (colonic epithelium-enriched)
RAI14 retinoic acid induced 14
RRAGD Ras-related GTP binding D
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
TRIM2 tripartite motif containing 2
ZNF586 zinc finger protein 586
ZNF91 zinc finger protein 91

decreased expression

Symbol Name
ABAT 4-aminobutyrate aminotransferase
ACAT1 acetyl-CoA acetyltransferase 1
ASS1 argininosuccinate synthase 1
CA12 carbonic anhydrase XII
CA2 carbonic anhydrase II
CORO1A coronin, actin binding protein, 1A
CXCL12 chemokine (C-X-C motif) ligand 12
CYBA cytochrome b-245, alpha polypeptide
EPCAM epithelial cell adhesion molecule
GPX3 glutathione peroxidase 3
HACD1 3-hydroxyacyl-CoA dehydratase 1
IGFBP4 insulin-like growth factor binding protein 4
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2
NREP neuronal regeneration related protein
PDZK1 PDZ domain containing 1
PROM1 prominin 1
QPRT quinolinate phosphoribosyltransferase
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B