Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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78 genes differentially expressed following the BRD-A28422330_4-[5-(4-methoxyphenyl)-3-phenyl-4,5-dihydro-1H-pyrazol-1-yl]benzenesulfonamide_A375_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
ANO1 | anoctamin 1, calcium activated chloride channel |
ARPP19 | cAMP-regulated phosphoprotein, 19kDa |
ASNS | asparagine synthetase (glutamine-hydrolyzing) |
ATF3 | activating transcription factor 3 |
CARS | cysteinyl-tRNA synthetase |
CD9 | CD9 molecule |
CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
CTH | cystathionine gamma-lyase |
CXCL8 | chemokine (C-X-C motif) ligand 8 |
DDIT3 | DNA-damage-inducible transcript 3 |
DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 |
ENO2 | enolase 2 (gamma, neuronal) |
FAM129A | family with sequence similarity 129, member A |
FLG | filaggrin |
G0S2 | G0/G1 switch 2 |
H1F0 | H1 histone family, member 0 |
HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
HMOX1 | heme oxygenase 1 |
HOPX | HOP homeobox |
ID4 | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein |
IGFBP3 | insulin-like growth factor binding protein 3 |
IGFBP5 | insulin-like growth factor binding protein 5 |
KLK10 | kallikrein-related peptidase 10 |
KLK11 | kallikrein-related peptidase 11 |
LIF | leukemia inhibitory factor |
LMO4 | LIM domain only 4 |
MAGEA6 | melanoma antigen family A6 |
NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
NUPR1 | nuclear protein, transcriptional regulator, 1 |
PCK2 | phosphoenolpyruvate carboxykinase 2 (mitochondrial) |
PHYH | phytanoyl-CoA 2-hydroxylase |
PPARD | peroxisome proliferator-activated receptor delta |
PSAT1 | phosphoserine aminotransferase 1 |
RAB25 | RAB25, member RAS oncogene family |
S100A14 | S100 calcium binding protein A14 |
SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 |
SHMT2 | serine hydroxymethyltransferase 2 (mitochondrial) |
SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
STC2 | stanniocalcin 2 |
VEGFA | vascular endothelial growth factor A |
XBP1 | X-box binding protein 1 |
Symbol | Name |
---|---|
ACTA2 | actin, alpha 2, smooth muscle, aorta |
ANPEP | alanyl (membrane) aminopeptidase |
ARNT2 | aryl-hydrocarbon receptor nuclear translocator 2 |
BAX | BCL2-associated X protein |
CD320 | CD320 molecule |
CD40 | CD40 molecule, TNF receptor superfamily member 5 |
CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) |
COCH | cochlin |
COL4A1 | collagen, type IV, alpha 1 |
CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 |
CYFIP2 | cytoplasmic FMR1 interacting protein 2 |
DCN | decorin |
FGFR3 | fibroblast growth factor receptor 3 |
FNBP1 | formin binding protein 1 |
GOLGA8H | golgin A8 family, member H |
IFITM1 | interferon induced transmembrane protein 1 |
IFITM2 | interferon induced transmembrane protein 2 |
IFITM3 | interferon induced transmembrane protein 3 |
IL27RA | interleukin 27 receptor, alpha |
LPAR6 | lysophosphatidic acid receptor 6 |
METTL7A | methyltransferase like 7A |
NID1 | nidogen 1 |
OLFM1 | olfactomedin 1 |
PBX3 | pre-B-cell leukemia homeobox 3 |
PVALB | parvalbumin |
RELN | reelin |
SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C |
SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 |
SORL1 | sortilin-related receptor, L(DLR class) A repeats containing |
SRGN | serglycin |
STOM | stomatin |
TGFB1 | transforming growth factor, beta 1 |
TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) |
TXNIP | thioredoxin interacting protein |
XIST | X inactive specific transcript (non-protein coding) |
ZIC1 | Zic family member 1 |