BRD-A33833419_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

82 genes differentially expressed following the BRD-A33833419_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
ATF3 activating transcription factor 3
BCL6 B-cell CLL/lymphoma 6
BZW2 basic leucine zipper and W2 domains 2
CA2 carbonic anhydrase II
CDK7 cyclin-dependent kinase 7
CHIC2 cysteine-rich hydrophobic domain 2
CLEC11A C-type lectin domain family 11, member A
CX3CR1 chemokine (C-X3-C motif) receptor 1
CYR61 cysteine-rich, angiogenic inducer, 61
DDAH1 dimethylarginine dimethylaminohydrolase 1
DDIT3 DNA-damage-inducible transcript 3
DUSP1 dual specificity phosphatase 1
EGR1 early growth response 1
EGR2 early growth response 2
EGR3 early growth response 3
EMP1 epithelial membrane protein 1
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
F3 coagulation factor III (thromboplastin, tissue factor)
FHL2 four and a half LIM domains 2
FOS FBJ murine osteosarcoma viral oncogene homolog
FOSB FBJ murine osteosarcoma viral oncogene homolog B
GADD45A growth arrest and DNA-damage-inducible, alpha
GCLM glutamate-cysteine ligase, modifier subunit
GEM GTP binding protein overexpressed in skeletal muscle
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
IFRD1 interferon-related developmental regulator 1
IRF8 interferon regulatory factor 8
IRS2 insulin receptor substrate 2
JMJD6 jumonji domain containing 6
JUN jun proto-oncogene
JUNB jun B proto-oncogene
KDM6B lysine (K)-specific demethylase 6B
KLF6 Kruppel-like factor 6
LST1 leukocyte specific transcript 1
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAP1LC3B microtubule-associated protein 1 light chain 3 beta
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MMP1 matrix metallopeptidase 1
MNDA myeloid cell nuclear differentiation antigen
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A
MYC v-myc avian myelocytomatosis viral oncogene homolog
NOTCH1 notch 1
NQO1 NAD(P)H dehydrogenase, quinone 1
NUPL1 nucleoporin like 1
P3H2 prolyl 3-hydroxylase 2
PLAC8 placenta-specific 8
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PSAP prosaposin
RGS2 regulator of G-protein signaling 2
RIOK3 RIO kinase 3
RNMT RNA (guanine-7-) methyltransferase
S100A9 S100 calcium binding protein A9
SERTAD2 SERTA domain containing 2
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
STC2 stanniocalcin 2
TMEM97 transmembrane protein 97
TNPO1 transportin 1
TXNRD1 thioredoxin reductase 1
UBB ubiquitin B

decreased expression

Symbol Name
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
CNN1 calponin 1, basic, smooth muscle
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
DEPTOR DEP domain containing MTOR-interacting protein
ITGA6 integrin, alpha 6
ITM2A integral membrane protein 2A
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
MCAM melanoma cell adhesion molecule
MPPED2 metallophosphoesterase domain containing 2
MRPL34 mitochondrial ribosomal protein L34
MYH11 myosin, heavy chain 11, smooth muscle
NR2F6 nuclear receptor subfamily 2, group F, member 6
PLN phospholamban
PSPH phosphoserine phosphatase
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TOP2A topoisomerase (DNA) II alpha 170kDa