| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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157 genes differentially expressed following the BRD-A35588707_-666_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ABHD4 | abhydrolase domain containing 4 |
| AIF1 | allograft inflammatory factor 1 |
| ANPEP | alanyl (membrane) aminopeptidase |
| ARL4C | ADP-ribosylation factor-like 4C |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding |
| BAG3 | BCL2-associated athanogene 3 |
| BEX4 | brain expressed, X-linked 4 |
| BHLHE40 | basic helix-loop-helix family, member e40 |
| BHLHE41 | basic helix-loop-helix family, member e41 |
| BLCAP | bladder cancer associated protein |
| BTG2 | BTG family, member 2 |
| C1ORF116 | chromosome 1 open reading frame 116 |
| C1ORF54 | chromosome 1 open reading frame 54 |
| C6ORF62 | chromosome 6 open reading frame 62 |
| CADM1 | cell adhesion molecule 1 |
| CAV1 | caveolin 1, caveolae protein, 22kDa |
| CCL5 | chemokine (C-C motif) ligand 5 |
| CCNG2 | cyclin G2 |
| CD24 | CD24 molecule |
| CD46 | CD46 molecule, complement regulatory protein |
| CD93 | CD93 molecule |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) |
| CLGN | calmegin |
| COL1A1 | collagen, type I, alpha 1 |
| COL4A2 | collagen, type IV, alpha 2 |
| CSTA | cystatin A (stefin A) |
| CTSZ | cathepsin Z |
| CXCL13 | chemokine (C-X-C motif) ligand 13 |
| DDB2 | damage-specific DNA binding protein 2, 48kDa |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DEFB1 | defensin, beta 1 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 |
| DUSP14 | dual specificity phosphatase 14 |
| EFNB2 | ephrin-B2 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 |
| ENTPD1 | ectonucleoside triphosphate diphosphohydrolase 1 |
| FAM134A | family with sequence similarity 134, member A |
| FBP1 | fructose-1,6-bisphosphatase 1 |
| FDXR | ferredoxin reductase |
| FN1 | fibronectin 1 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha |
| IGF1 | insulin-like growth factor 1 (somatomedin C) |
| INHBB | inhibin, beta B |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 |
| KRT14 | keratin 14, type I |
| KRT17 | keratin 17, type I |
| LBH | limb bud and heart development |
| LRP10 | low density lipoprotein receptor-related protein 10 |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B |
| MICALL1 | MICAL-like 1 |
| MMP12 | matrix metallopeptidase 12 |
| MSMB | microseminoprotein, beta- |
| NKX3-1 | NK3 homeobox 1 |
| NNMT | nicotinamide N-methyltransferase |
| PINK1 | PTEN induced putative kinase 1 |
| PLK2 | polo-like kinase 2 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 |
| PPL | periplakin |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
| PSAP | prosaposin |
| PTGER4 | prostaglandin E receptor 4 (subtype EP4) |
| PTHLH | parathyroid hormone-like hormone |
| S100A2 | S100 calcium binding protein A2 |
| SAP18 | Sin3A-associated protein, 18kDa |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit |
| SESN1 | sestrin 1 |
| SFN | stratifin |
| SLC2A5 | solute carrier family 2 (facilitated glucose/fructose transporter), member 5 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 |
| SLC46A3 | solute carrier family 46, member 3 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 |
| SNAI2 | snail family zinc finger 2 |
| SQRDL | sulfide quinone reductase-like (yeast) |
| TDO2 | tryptophan 2,3-dioxygenase |
| TGM2 | transglutaminase 2 |
| THBS1 | thrombospondin 1 |
| TIGAR | TP53 induced glycolysis regulatory phosphatase |
| TRIM22 | tripartite motif containing 22 |
| TRIM38 | tripartite motif containing 38 |
| TWF2 | twinfilin actin binding protein 2 |
| ZMAT3 | zinc finger, matrin-type 3 |
| Symbol | Name |
|---|---|
| ADAM10 | ADAM metallopeptidase domain 10 |
| AFP | alpha-fetoprotein |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) |
| AURKA | aurora kinase A |
| BMPR1A | bone morphogenetic protein receptor, type IA |
| BUB1 | BUB1 mitotic checkpoint serine/threonine kinase |
| CCNA2 | cyclin A2 |
| CCNB2 | cyclin B2 |
| CHL1 | cell adhesion molecule L1-like |
| CLIC4 | chloride intracellular channel 4 |
| CRIP1 | cysteine-rich protein 1 (intestinal) |
| CXCL14 | chemokine (C-X-C motif) ligand 14 |
| DCK | deoxycytidine kinase |
| DDX10 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 |
| DDX21 | DEAD (Asp-Glu-Ala-Asp) box helicase 21 |
| DLC1 | DLC1 Rho GTPase activating protein |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 |
| DMD | dystrophin |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A |
| F3 | coagulation factor III (thromboplastin, tissue factor) |
| FOXJ3 | forkhead box J3 |
| GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) |
| GGH | gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) |
| GPC3 | glypican 3 |
| GRIA2 | glutamate receptor, ionotropic, AMPA 2 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 |
| IKBKAP | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein |
| ITGA6 | integrin, alpha 6 |
| KLF6 | Kruppel-like factor 6 |
| LCN2 | lipocalin 2 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 |
| MAP7 | microtubule-associated protein 7 |
| MBNL1 | muscleblind-like splicing regulator 1 |
| MELK | maternal embryonic leucine zipper kinase |
| MUC16 | mucin 16, cell surface associated |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog |
| PAM | peptidylglycine alpha-amidating monooxygenase |
| PBK | PDZ binding kinase |
| PLK1 | polo-like kinase 1 |
| PRC1 | protein regulator of cytokinesis 1 |
| PRSS2 | protease, serine, 2 (trypsin 2) |
| PSD3 | pleckstrin and Sec7 domain containing 3 |
| PTCH1 | patched 1 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 |
| PTPRD | protein tyrosine phosphatase, receptor type, D |
| PTPRZ1 | protein tyrosine phosphatase, receptor-type, Z polypeptide 1 |
| QKI | QKI, KH domain containing, RNA binding |
| RHOBTB3 | Rho-related BTB domain containing 3 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) |
| RUFY3 | RUN and FYVE domain containing 3 |
| S100P | S100 calcium binding protein P |
| SATB2 | SATB homeobox 2 |
| SIK1 | salt-inducible kinase 1 |
| SLC11A2 | solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 |
| SWAP70 | SWAP switching B-cell complex 70kDa subunit |
| TBC1D4 | TBC1 domain family, member 4 |
| TCF12 | transcription factor 12 |
| TCF4 | transcription factor 4 |
| TFF3 | trefoil factor 3 (intestinal) |
| TGFBR3 | transforming growth factor, beta receptor III |
| TNC | tenascin C |
| TOP2A | topoisomerase (DNA) II alpha 170kDa |
| TSEN2 | TSEN2 tRNA splicing endonuclease subunit |
| TXN | thioredoxin |
| UBE2C | ubiquitin-conjugating enzyme E2C |
| USP3 | ubiquitin specific peptidase 3 |
| VCAM1 | vascular cell adhesion molecule 1 |
