BRD-A35588707_-666_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

52 genes differentially expressed following the BRD-A35588707_-666_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
BEX4 brain expressed, X-linked 4
BLNK B-cell linker
BTG3 BTG family, member 3
CCNE2 cyclin E2
CD24 CD24 molecule
CEBPD CCAAT/enhancer binding protein (C/EBP), delta
CHGB chromogranin B
CXCL13 chemokine (C-X-C motif) ligand 13
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila)
GMPR guanosine monophosphate reductase
IL13RA2 interleukin 13 receptor, alpha 2
QPCT glutaminyl-peptide cyclotransferase
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
TMEM5 transmembrane protein 5

decreased expression

Symbol Name
ALCAM activated leukocyte cell adhesion molecule
AURKA aurora kinase A
CAV1 caveolin 1, caveolae protein, 22kDa
CAV2 caveolin 2
CDC20 cell division cycle 20
CENPA centromere protein A
CENPF centromere protein F, 350/400kDa
DKK1 dickkopf WNT signaling pathway inhibitor 1
EPCAM epithelial cell adhesion molecule
EPS8 epidermal growth factor receptor pathway substrate 8
ERBB2 erb-b2 receptor tyrosine kinase 2
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FOXJ3 forkhead box J3
GPX2 glutathione peroxidase 2
ITGA6 integrin, alpha 6
KIF14 kinesin family member 14
KIF20A kinesin family member 20A
LPL lipoprotein lipase
MBNL2 muscleblind-like splicing regulator 2
METTL7A methyltransferase like 7A
MGLL monoglyceride lipase
MLPH melanophilin
MYC v-myc avian myelocytomatosis viral oncogene homolog
NRIP1 nuclear receptor interacting protein 1
NTS neurotensin
PLK1 polo-like kinase 1
PLK2 polo-like kinase 2
PPARG peroxisome proliferator-activated receptor gamma
PTPN12 protein tyrosine phosphatase, non-receptor type 12
RASA1 RAS p21 protein activator (GTPase activating protein) 1
S100P S100 calcium binding protein P
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SPTBN1 spectrin, beta, non-erythrocytic 1
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TOX3 TOX high mobility group box family member 3
ZMIZ1 zinc finger, MIZ-type containing 1