BRD-A35912562_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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69 genes differentially expressed following the BRD-A35912562_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AUTS2 autism susceptibility candidate 2
BANK1 B-cell scaffold protein with ankyrin repeats 1
CCDC86 coiled-coil domain containing 86
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CTBP2 C-terminal binding protein 2
DES desmin
EIF5A eukaryotic translation initiation factor 5A
ENC1 ectodermal-neural cortex 1 (with BTB domain)
FKBP11 FK506 binding protein 11, 19 kDa
GDF15 growth differentiation factor 15
GREM1 gremlin 1, DAN family BMP antagonist
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
HMOX1 heme oxygenase 1
HOPX HOP homeobox
HSPA1A heat shock 70kDa protein 1A
IL1R1 interleukin 1 receptor, type I
IL7R interleukin 7 receptor
KLRB1 killer cell lectin-like receptor subfamily B, member 1
LAMP3 lysosomal-associated membrane protein 3
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
NR1D2 nuclear receptor subfamily 1, group D, member 2
NXN nucleoredoxin
PPAP2B phosphatidic acid phosphatase type 2B
PTER phosphotriesterase related
RBPMS RNA binding protein with multiple splicing
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
SCG5 secretogranin V
SLC38A2 solute carrier family 38, member 2
TGIF1 TGFB-induced factor homeobox 1
TMPRSS2 transmembrane protease, serine 2
TRBC1 T cell receptor beta constant 1
TSPAN12 tetraspanin 12
VAMP8 vesicle-associated membrane protein 8

decreased expression

Symbol Name
ARFIP2 ADP-ribosylation factor interacting protein 2
ASPH aspartate beta-hydroxylase
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide
C1S complement component 1, s subcomponent
CADM1 cell adhesion molecule 1
CAST calpastatin
CD59 CD59 molecule, complement regulatory protein
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
COL3A1 collagen, type III, alpha 1
COMP cartilage oligomeric matrix protein
DCN decorin
FABP4 fatty acid binding protein 4, adipocyte
FABP7 fatty acid binding protein 7, brain
G0S2 G0/G1 switch 2
GPM6A glycoprotein M6A
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KRT14 keratin 14, type I
LRRC17 leucine rich repeat containing 17
METRN meteorin, glial cell differentiation regulator
MIA melanoma inhibitory activity
MKNK1 MAP kinase interacting serine/threonine kinase 1
PCDH9 protocadherin 9
PLIN1 perilipin 1
S100A2 S100 calcium binding protein A2
S100A6 S100 calcium binding protein A6
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SCG2 secretogranin II
SNX7 sorting nexin 7
SPARCL1 SPARC-like 1 (hevin)
SRGN serglycin
SRI sorcin
TFRC transferrin receptor
TM4SF1 transmembrane 4 L six family member 1