| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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103 genes differentially expressed following the BRD-A36630025_-666_A375_6.0_h_0.35_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ADO | 2-aminoethanethiol (cysteamine) dioxygenase |
| ADRB2 | adrenoceptor beta 2, surface |
| ALOX5 | arachidonate 5-lipoxygenase |
| BTG2 | BTG family, member 2 |
| CCL2 | chemokine (C-C motif) ligand 2 |
| CD86 | CD86 molecule |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 |
| CLC | Charcot-Leyden crystal galectin |
| CPA3 | carboxypeptidase A3 (mast cell) |
| CPE | carboxypeptidase E |
| CTSK | cathepsin K |
| CXCL10 | chemokine (C-X-C motif) ligand 10 |
| CYCS | cytochrome c, somatic |
| DCN | decorin |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 |
| FAS | Fas cell surface death receptor |
| FDXR | ferredoxin reductase |
| FHL2 | four and a half LIM domains 2 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha |
| GADD45B | growth arrest and DNA-damage-inducible, beta |
| GCH1 | GTP cyclohydrolase 1 |
| GEM | GTP binding protein overexpressed in skeletal muscle |
| GIMAP6 | GTPase, IMAP family member 6 |
| ICAM1 | intercellular adhesion molecule 1 |
| IL32 | interleukin 32 |
| IL6 | interleukin 6 |
| JUNB | jun B proto-oncogene |
| KLF10 | Kruppel-like factor 10 |
| KLHL21 | kelch-like family member 21 |
| LXN | latexin |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B |
| MIR22HG | MIR22 host gene |
| MMP12 | matrix metallopeptidase 12 |
| MPO | myeloperoxidase |
| NDRG1 | N-myc downstream regulated 1 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| PLAU | plasminogen activator, urokinase |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 |
| RHOB | ras homolog family member B |
| RRAD | Ras-related associated with diabetes |
| S100A8 | S100 calcium binding protein A8 |
| S100A9 | S100 calcium binding protein A9 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 |
| SDC4 | syndecan 4 |
| SESN1 | sestrin 1 |
| SFRP4 | secreted frizzled-related protein 4 |
| SLC7A7 | solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 |
| TFRC | transferrin receptor |
| TOB1 | transducer of ERBB2, 1 |
| TPSAB1 | tryptase alpha/beta 1 |
| TPSB2 | tryptase beta 2 (gene/pseudogene) |
| TUBB2A | tubulin, beta 2A class IIa |
| ZMAT3 | zinc finger, matrin-type 3 |
| Symbol | Name |
|---|---|
| ADAM10 | ADAM metallopeptidase domain 10 |
| AGTR1 | angiotensin II receptor, type 1 |
| AURKA | aurora kinase A |
| CCNA2 | cyclin A2 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) |
| CENPF | centromere protein F, 350/400kDa |
| CHEK2 | checkpoint kinase 2 |
| CIT | citron rho-interacting serine/threonine kinase |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) |
| DARS | aspartyl-tRNA synthetase |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 |
| EHBP1 | EH domain binding protein 1 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 |
| ERBB3 | erb-b2 receptor tyrosine kinase 3 |
| FOXD1 | forkhead box D1 |
| GRIA2 | glutamate receptor, ionotropic, AMPA 2 |
| IGF1R | insulin-like growth factor 1 receptor |
| ITGA6 | integrin, alpha 6 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) |
| LBR | lamin B receptor |
| MAP1B | microtubule-associated protein 1B |
| MAST2 | microtubule associated serine/threonine kinase 2 |
| MBNL1 | muscleblind-like splicing regulator 1 |
| MBNL2 | muscleblind-like splicing regulator 2 |
| MET | MET proto-oncogene, receptor tyrosine kinase |
| MGLL | monoglyceride lipase |
| MPRIP | myosin phosphatase Rho interacting protein |
| NETO2 | neuropilin (NRP) and tolloid (TLL)-like 2 |
| NRIP1 | nuclear receptor interacting protein 1 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 |
| PDS5A | PDS5 cohesin associated factor A |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 |
| PODXL | podocalyxin-like |
| PPARG | peroxisome proliferator-activated receptor gamma |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A |
| PRSS23 | protease, serine, 23 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 |
| RASA1 | RAS p21 protein activator (GTPase activating protein) 1 |
| RREB1 | ras responsive element binding protein 1 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| TBL1X | transducin (beta)-like 1X-linked |
| TOP2A | topoisomerase (DNA) II alpha 170kDa |
| XPO1 | exportin 1 |
