Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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187 genes differentially expressed following the BRD-A36630025_-666_HEPG2_6.0_h_0.35_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
ADM | adrenomedullin |
ADO | 2-aminoethanethiol (cysteamine) dioxygenase |
ANGPTL2 | angiopoietin-like 2 |
AQP1 | aquaporin 1 (Colton blood group) |
ARL4C | ADP-ribosylation factor-like 4C |
ARMCX2 | armadillo repeat containing, X-linked 2 |
ASPN | asporin |
ATF3 | activating transcription factor 3 |
BEX4 | brain expressed, X-linked 4 |
BHLHE41 | basic helix-loop-helix family, member e41 |
BTG2 | BTG family, member 2 |
C10ORF10 | chromosome 10 open reading frame 10 |
CADM1 | cell adhesion molecule 1 |
CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain |
CD9 | CD9 molecule |
CD93 | CD93 molecule |
CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 |
CDH1 | cadherin 1, type 1, E-cadherin (epithelial) |
CECR1 | cat eye syndrome chromosome region, candidate 1 |
CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) |
CILP | cartilage intermediate layer protein, nucleotide pyrophosphohydrolase |
CLEC2B | C-type lectin domain family 2, member B |
COL11A1 | collagen, type XI, alpha 1 |
COL6A1 | collagen, type VI, alpha 1 |
COL6A2 | collagen, type VI, alpha 2 |
CRABP2 | cellular retinoic acid binding protein 2 |
DDIT4 | DNA-damage-inducible transcript 4 |
DEFB1 | defensin, beta 1 |
DERL1 | derlin 1 |
DUSP14 | dual specificity phosphatase 14 |
EFNB2 | ephrin-B2 |
EGLN3 | egl-9 family hypoxia-inducible factor 3 |
EMP1 | epithelial membrane protein 1 |
ENPP4 | ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative) |
FAM129A | family with sequence similarity 129, member A |
FASTKD5 | FAST kinase domains 5 |
FLT1 | fms-related tyrosine kinase 1 |
FZD6 | frizzled class receptor 6 |
GADD45A | growth arrest and DNA-damage-inducible, alpha |
GADD45B | growth arrest and DNA-damage-inducible, beta |
GEM | GTP binding protein overexpressed in skeletal muscle |
GPNMB | glycoprotein (transmembrane) nmb |
HES1 | hes family bHLH transcription factor 1 |
HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 |
HOXA5 | homeobox A5 |
IGFBP5 | insulin-like growth factor binding protein 5 |
JCHAIN | joining chain of multimeric IgA and IgM |
KRT14 | keratin 14, type I |
KRT17 | keratin 17, type I |
KRT19 | keratin 19, type I |
KRT5 | keratin 5, type II |
KRT6A | keratin 6A, type II |
LAPTM5 | lysosomal protein transmembrane 5 |
LUM | lumican |
LY96 | lymphocyte antigen 96 |
NDRG1 | N-myc downstream regulated 1 |
NDUFA4L2 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2 |
NLRP2 | NLR family, pyrin domain containing 2 |
OLFML2A | olfactomedin-like 2A |
PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) |
PDGFRA | platelet-derived growth factor receptor, alpha polypeptide |
PECAM1 | platelet/endothelial cell adhesion molecule 1 |
PLAU | plasminogen activator, urokinase |
PLVAP | plasmalemma vesicle associated protein |
PLXNB2 | plexin B2 |
PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 |
PPL | periplakin |
PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
PTGER4 | prostaglandin E receptor 4 (subtype EP4) |
RAB25 | RAB25, member RAS oncogene family |
S100A2 | S100 calcium binding protein A2 |
S100A8 | S100 calcium binding protein A8 |
SCGB2A1 | secretoglobin, family 2A, member 1 |
SCN3A | sodium channel, voltage gated, type III alpha subunit |
SCPEP1 | serine carboxypeptidase 1 |
SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C |
SERPINI1 | serpin peptidase inhibitor, clade I (neuroserpin), member 1 |
SH3BGRL | SH3 domain binding glutamate-rich protein like |
SH3YL1 | SH3 and SYLF domain containing 1 |
SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 |
SNAI2 | snail family zinc finger 2 |
SOX9 | SRY (sex determining region Y)-box 9 |
SPINT2 | serine peptidase inhibitor, Kunitz type, 2 |
ST14 | suppression of tumorigenicity 14 (colon carcinoma) |
STC1 | stanniocalcin 1 |
STC2 | stanniocalcin 2 |
TACSTD2 | tumor-associated calcium signal transducer 2 |
THBS2 | thrombospondin 2 |
TIGAR | TP53 induced glycolysis regulatory phosphatase |
TMSB15A | thymosin beta 15a |
TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 |
TRIB2 | tribbles pseudokinase 2 |
TRIM2 | tripartite motif containing 2 |
TXNIP | thioredoxin interacting protein |
VEGFA | vascular endothelial growth factor A |
VTCN1 | V-set domain containing T cell activation inhibitor 1 |
XIST | X inactive specific transcript (non-protein coding) |
ZFPM2 | zinc finger protein, FOG family member 2 |
ZNF264 | zinc finger protein 264 |
Symbol | Name |
---|---|
ADGRG2 | adhesion G protein-coupled receptor G2 |
ADGRG6 | adhesion G protein-coupled receptor G6 |
AGTR1 | angiotensin II receptor, type 1 |
AHSG | alpha-2-HS-glycoprotein |
AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) |
AKR1C1 | aldo-keto reductase family 1, member C1 |
AKR1C2 | aldo-keto reductase family 1, member C2 |
AKR1C3 | aldo-keto reductase family 1, member C3 |
ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 |
AMD1 | adenosylmethionine decarboxylase 1 |
APOA2 | apolipoprotein A-II |
AURKA | aurora kinase A |
BEX1 | brain expressed, X-linked 1 |
C8ORF4 | chromosome 8 open reading frame 4 |
CCNA2 | cyclin A2 |
CDH2 | cadherin 2, type 1, N-cadherin (neuronal) |
CDK19 | cyclin-dependent kinase 19 |
CDK7 | cyclin-dependent kinase 7 |
CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 |
CKS2 | CDC28 protein kinase regulatory subunit 2 |
CPS1 | carbamoyl-phosphate synthase 1, mitochondrial |
CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 |
DDX10 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 |
DIMT1 | DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae) |
DKK1 | dickkopf WNT signaling pathway inhibitor 1 |
EIF1AY | eukaryotic translation initiation factor 1A, Y-linked |
ELOVL2 | ELOVL fatty acid elongase 2 |
FGB | fibrinogen beta chain |
FGF13 | fibroblast growth factor 13 |
FGG | fibrinogen gamma chain |
FOLR1 | folate receptor 1 (adult) |
GMDS | GDP-mannose 4,6-dehydratase |
GSPT1 | G1 to S phase transition 1 |
HSPA8 | heat shock 70kDa protein 8 |
IGHM | immunoglobulin heavy constant mu |
JMJD6 | jumonji domain containing 6 |
KIAA0368 | KIAA0368 |
KPNB1 | karyopherin (importin) beta 1 |
LAMB1 | laminin, beta 1 |
LYRM4 | LYR motif containing 4 |
LYZ | lysozyme |
MAPKAPK2 | mitogen-activated protein kinase-activated protein kinase 2 |
MARCKSL1 | MARCKS-like 1 |
MAST2 | microtubule associated serine/threonine kinase 2 |
MELK | maternal embryonic leucine zipper kinase |
MNAT1 | MNAT CDK-activating kinase assembly factor 1 |
MRPS30 | mitochondrial ribosomal protein S30 |
MYC | v-myc avian myelocytomatosis viral oncogene homolog |
NAA38 | N(alpha)-acetyltransferase 38, NatC auxiliary subunit |
NR2F2 | nuclear receptor subfamily 2, group F, member 2 |
OXTR | oxytocin receptor |
PBK | PDZ binding kinase |
PHACTR2 | phosphatase and actin regulator 2 |
PLK1 | polo-like kinase 1 |
PNN | pinin, desmosome associated protein |
POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit |
PRC1 | protein regulator of cytokinesis 1 |
PTPN12 | protein tyrosine phosphatase, non-receptor type 12 |
QKI | QKI, KH domain containing, RNA binding |
RAP1GAP | RAP1 GTPase activating protein |
RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 |
S100P | S100 calcium binding protein P |
SELENBP1 | selenium binding protein 1 |
SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
SPTBN1 | spectrin, beta, non-erythrocytic 1 |
SRC | SRC proto-oncogene, non-receptor tyrosine kinase |
STOM | stomatin |
SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein |
SYT1 | synaptotagmin I |
TBC1D4 | TBC1 domain family, member 4 |
TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) |
TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) |
TEX10 | testis expressed 10 |
TF | transferrin |
TFF1 | trefoil factor 1 |
TFF3 | trefoil factor 3 (intestinal) |
TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) |
TGFBI | transforming growth factor, beta-induced, 68kDa |
TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) |
TLE1 | transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) |
TRIM14 | tripartite motif containing 14 |
TSPAN8 | tetraspanin 8 |
TXNRD1 | thioredoxin reductase 1 |
UBE3C | ubiquitin protein ligase E3C |
USP7 | ubiquitin specific peptidase 7 (herpes virus-associated) |
ZFAND5 | zinc finger, AN1-type domain 5 |
ZMYND8 | zinc finger, MYND-type containing 8 |