BRD-A37704979_SB-203580_HEPG2_24_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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71 genes differentially expressed following the BRD-A37704979_SB-203580_HEPG2_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ANGPT1 angiopoietin 1
ARHGAP29 Rho GTPase activating protein 29
BASP1 brain abundant, membrane attached signal protein 1
CD58 CD58 molecule
CLEC2B C-type lectin domain family 2, member B
DUSP6 dual specificity phosphatase 6
EGR1 early growth response 1
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2)
EPCAM epithelial cell adhesion molecule
EVI2A ecotropic viral integration site 2A
FHL2 four and a half LIM domains 2
FOSL1 FOS-like antigen 1
GEM GTP binding protein overexpressed in skeletal muscle
GJA1 gap junction protein, alpha 1, 43kDa
GLRX glutaredoxin (thioltransferase)
HOPX HOP homeobox
HOXB6 homeobox B6
IER3 immediate early response 3
IGFBP7 insulin-like growth factor binding protein 7
IL13RA2 interleukin 13 receptor, alpha 2
KRT19 keratin 19, type I
KRT7 keratin 7, type II
LAMB1 laminin, beta 1
LAPTM4B lysosomal protein transmembrane 4 beta
LPAR1 lysophosphatidic acid receptor 1
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MYOF myoferlin
NDFIP1 Nedd4 family interacting protein 1
NPY neuropeptide Y
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2
RGS5 regulator of G-protein signaling 5
S100A6 S100 calcium binding protein A6
SCG5 secretogranin V
SLC35G2 solute carrier family 35, member G2
SNAP25 synaptosomal-associated protein, 25kDa
SOX4 SRY (sex determining region Y)-box 4
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor)
TBX3 T-box 3
TM4SF1 transmembrane 4 L six family member 1
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TOMM34 translocase of outer mitochondrial membrane 34
TUBB6 tubulin, beta 6 class V
VIM vimentin
VNN1 vanin 1
WBP5 WW domain binding protein 5

decreased expression

Symbol Name
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
AK4 adenylate kinase 4
AZGP1 alpha-2-glycoprotein 1, zinc-binding
CCL5 chemokine (C-C motif) ligand 5
CDK14 cyclin-dependent kinase 14
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CES1 carboxylesterase 1
CLIC3 chloride intracellular channel 3
CYB5A cytochrome b5 type A (microsomal)
DEPTOR DEP domain containing MTOR-interacting protein
FAM69A family with sequence similarity 69, member A
GLUL glutamate-ammonia ligase
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HMOX1 heme oxygenase 1
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IGHM immunoglobulin heavy constant mu
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MCM5 minichromosome maintenance complex component 5
NOTCH3 notch 3
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
RAD51C RAD51 paralog C
SCD stearoyl-CoA desaturase (delta-9-desaturase)
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
ZMYM2 zinc finger, MYM-type 2