BRD-A38878059_BL-077_PHH_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

52 genes differentially expressed following the BRD-A38878059_BL-077_PHH_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ASAP2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
BST2 bone marrow stromal cell antigen 2
C10ORF10 chromosome 10 open reading frame 10
CD36 CD36 molecule (thrombospondin receptor)
CDKN2A cyclin-dependent kinase inhibitor 2A
ESR1 estrogen receptor 1
FABP4 fatty acid binding protein 4, adipocyte
IDS iduronate 2-sulfatase
IFI44L interferon-induced protein 44-like
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
ISG15 ISG15 ubiquitin-like modifier
KIF14 kinesin family member 14
LEPROT leptin receptor overlapping transcript
METRN meteorin, glial cell differentiation regulator
SST somatostatin
STC2 stanniocalcin 2
THBD thrombomodulin

decreased expression

Symbol Name
AIM1 absent in melanoma 1
ATP2C1 ATPase, Ca++ transporting, type 2C, member 1
BEX1 brain expressed, X-linked 1
C6ORF62 chromosome 6 open reading frame 62
CD52 CD52 molecule
CD69 CD69 molecule
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CSTA cystatin A (stefin A)
DICER1 dicer 1, ribonuclease type III
DLD dihydrolipoamide dehydrogenase
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FMO2 flavin containing monooxygenase 2 (non-functional)
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
GCH1 GTP cyclohydrolase 1
IGKV1-5 immunoglobulin kappa variable 1-5
INSM1 insulinoma-associated 1
MSMB microseminoprotein, beta-
NRIP1 nuclear receptor interacting protein 1
PCP4 Purkinje cell protein 4
POLR2K polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa
PRUNE2 prune homolog 2 (Drosophila)
REEP1 receptor accessory protein 1
RGS1 regulator of G-protein signaling 1
RPS11 ribosomal protein S11
RRM1 ribonucleotide reductase M1
S100A13 S100 calcium binding protein A13
S100P S100 calcium binding protein P
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
SRSF1 serine/arginine-rich splicing factor 1
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
ZBTB20 zinc finger and BTB domain containing 20
ZBTB38 zinc finger and BTB domain containing 38
Funding