BRD-A38878059_BL-077_VCAP_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

98 genes differentially expressed following the BRD-A38878059_BL-077_VCAP_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKAP17A A kinase (PRKA) anchor protein 17A
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ANKMY2 ankyrin repeat and MYND domain containing 2
ANPEP alanyl (membrane) aminopeptidase
ANXA2 annexin A2
ASRGL1 asparaginase like 1
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
ATP6V1G1 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1
CAPN2 calpain 2, (m/II) large subunit
COBL cordon-bleu WH2 repeat protein
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
EDEM1 ER degradation enhancer, mannosidase alpha-like 1
EGFR epidermal growth factor receptor
EZR ezrin
FBXO21 F-box protein 21
FGFR3 fibroblast growth factor receptor 3
FKBP5 FK506 binding protein 5
FOXO3 forkhead box O3
FZD5 frizzled class receptor 5
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5
GLRX glutaredoxin (thioltransferase)
GPER1 G protein-coupled estrogen receptor 1
GREB1 growth regulation by estrogen in breast cancer 1
GULP1 GULP, engulfment adaptor PTB domain containing 1
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
IGF1R insulin-like growth factor 1 receptor
INPP1 inositol polyphosphate-1-phosphatase
KRT19 keratin 19, type I
LRRC17 leucine rich repeat containing 17
MIR22HG MIR22 host gene
MSX1 msh homeobox 1
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase)
NET1 neuroepithelial cell transforming 1
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NSDHL NAD(P) dependent steroid dehydrogenase-like
OLFML2A olfactomedin-like 2A
PBX1 pre-B-cell leukemia homeobox 1
PCDH7 protocadherin 7
PDZK1 PDZ domain containing 1
PROM1 prominin 1
RHOBTB3 Rho-related BTB domain containing 3
S100A12 S100 calcium binding protein A12
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
S100P S100 calcium binding protein P
SAP30 Sin3A-associated protein, 30kDa
SCGB1D2 secretoglobin, family 1D, member 2
SCGB2A2 secretoglobin, family 2A, member 2
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SPDEF SAM pointed domain containing ETS transcription factor
SRGN serglycin
TFF1 trefoil factor 1
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
ZBTB18 zinc finger and BTB domain containing 18

decreased expression

Symbol Name
A2M alpha-2-macroglobulin
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ADGRE5 adhesion G protein-coupled receptor E5
ADRB2 adrenoceptor beta 2, surface
ATP10B ATPase, class V, type 10B
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein)
CALCA calcitonin-related polypeptide alpha
CCDC85B coiled-coil domain containing 85B
CCND1 cyclin D1
CEMIP cell migration inducing protein, hyaluronan binding
CHST1 carbohydrate (keratan sulfate Gal-6) sulfotransferase 1
CXCL14 chemokine (C-X-C motif) ligand 14
DIAPH2 diaphanous-related formin 2
F12 coagulation factor XII (Hageman factor)
FAM46A family with sequence similarity 46, member A
FBL fibrillarin
GPI glucose-6-phosphate isomerase
GRWD1 glutamate-rich WD repeat containing 1
HOXD1 homeobox D1
IGFBP3 insulin-like growth factor binding protein 3
IL1RAP interleukin 1 receptor accessory protein
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
MYC v-myc avian myelocytomatosis viral oncogene homolog
NCAM1 neural cell adhesion molecule 1
NFIB nuclear factor I/B
NHP2 NHP2 ribonucleoprotein
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain)
NOP16 NOP16 nucleolar protein
PRSS21 protease, serine, 21 (testisin)
RPS4Y1 ribosomal protein S4, Y-linked 1
SNX10 sorting nexin 10
SRSF7 serine/arginine-rich splicing factor 7
ST7 suppression of tumorigenicity 7
TM4SF1 transmembrane 4 L six family member 1
TMEM97 transmembrane protein 97
TRIB1 tribbles pseudokinase 1
TSPAN8 tetraspanin 8
TUBB2B tubulin, beta 2B class IIb
TYRP1 tyrosinase-related protein 1
Funding