Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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99 genes differentially expressed following the BRD-A39969961_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
ADM | adrenomedullin |
BCL6 | B-cell CLL/lymphoma 6 |
CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) |
CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) |
CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 |
CLDN3 | claudin 3 |
CP | ceruloplasmin (ferroxidase) |
CSTA | cystatin A (stefin A) |
DPP4 | dipeptidyl-peptidase 4 |
EFEMP1 | EGF containing fibulin-like extracellular matrix protein 1 |
ENO1 | enolase 1, (alpha) |
F3 | coagulation factor III (thromboplastin, tissue factor) |
FAM69A | family with sequence similarity 69, member A |
GJA1 | gap junction protein, alpha 1, 43kDa |
GLUL | glutamate-ammonia ligase |
GNLY | granulysin |
HILPDA | hypoxia inducible lipid droplet-associated |
HOPX | HOP homeobox |
HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) |
IGFBP2 | insulin-like growth factor binding protein 2, 36kDa |
IGHM | immunoglobulin heavy constant mu |
KCTD5 | potassium channel tetramerization domain containing 5 |
LIMA1 | LIM domain and actin binding 1 |
LOC100505650 | uncharacterized LOC100505650 |
MAOA | monoamine oxidase A |
MEIS2 | Meis homeobox 2 |
MPPED2 | metallophosphoesterase domain containing 2 |
NOL3 | nucleolar protein 3 (apoptosis repressor with CARD domain) |
P3H2 | prolyl 3-hydroxylase 2 |
PAX6 | paired box 6 |
PPIC | peptidylprolyl isomerase C (cyclophilin C) |
RBP1 | retinol binding protein 1, cellular |
RHOBTB3 | Rho-related BTB domain containing 3 |
RPL31 | ribosomal protein L31 |
SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 |
SFTPB | surfactant protein B |
SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 |
SLC34A2 | solute carrier family 34 (type II sodium/phosphate cotransporter), member 2 |
SPINK2 | serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) |
SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) |
SRD5A1 | steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) |
TBC1D9B | TBC1 domain family, member 9B (with GRAM domain) |
TMEM158 | transmembrane protein 158 (gene/pseudogene) |
VEGFA | vascular endothelial growth factor A |
WT1 | Wilms tumor 1 |
XIST | X inactive specific transcript (non-protein coding) |
Symbol | Name |
---|---|
ADIRF | adipogenesis regulatory factor |
AKR1C3 | aldo-keto reductase family 1, member C3 |
ARHGAP29 | Rho GTPase activating protein 29 |
ATP6V0B | ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b |
BICC1 | BicC family RNA binding protein 1 |
BRCA1 | breast cancer 1, early onset |
CCNE2 | cyclin E2 |
COL14A1 | collagen, type XIV, alpha 1 |
COMP | cartilage oligomeric matrix protein |
CTSK | cathepsin K |
CXCL12 | chemokine (C-X-C motif) ligand 12 |
CYBA | cytochrome b-245, alpha polypeptide |
DDB2 | damage-specific DNA binding protein 2, 48kDa |
DEFB1 | defensin, beta 1 |
ELK3 | ELK3, ETS-domain protein (SRF accessory protein 2) |
FAM171A1 | family with sequence similarity 171, member A1 |
FBN1 | fibrillin 1 |
FLRT2 | fibronectin leucine rich transmembrane protein 2 |
GDF15 | growth differentiation factor 15 |
GNG11 | guanine nucleotide binding protein (G protein), gamma 11 |
GPRC5A | G protein-coupled receptor, class C, group 5, member A |
GPX2 | glutathione peroxidase 2 |
HOXC6 | homeobox C6 |
IGF1R | insulin-like growth factor 1 receptor |
ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) |
KDSR | 3-ketodihydrosphingosine reductase |
KLHL21 | kelch-like family member 21 |
LUC7L3 | LUC7-like 3 (S. cerevisiae) |
MARCKS | myristoylated alanine-rich protein kinase C substrate |
MFAP5 | microfibrillar associated protein 5 |
MGLL | monoglyceride lipase |
MGP | matrix Gla protein |
NET1 | neuroepithelial cell transforming 1 |
PCDH9 | protocadherin 9 |
PPIF | peptidylprolyl isomerase F |
PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme |
PRRG1 | proline rich Gla (G-carboxyglutamic acid) 1 |
RPS27L | ribosomal protein S27-like |
S100P | S100 calcium binding protein P |
SCUBE2 | signal peptide, CUB domain, EGF-like 2 |
SFN | stratifin |
SLC19A2 | solute carrier family 19 (thiamine transporter), member 2 |
SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 |
SRPX | sushi-repeat containing protein, X-linked |
STOM | stomatin |
TFAP2B | transcription factor AP-2 beta (activating enhancer binding protein 2 beta) |
THBS1 | thrombospondin 1 |
TOB1 | transducer of ERBB2, 1 |
TSPAN8 | tetraspanin 8 |
TSPYL5 | TSPY-like 5 |
TUBA4A | tubulin, alpha 4a |
WWP1 | WW domain containing E3 ubiquitin protein ligase 1 |