| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
| Downloads & Tools |
291 genes differentially expressed following the BRD-A39996500_radicicol_BT20_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ABHD4 | abhydrolase domain containing 4 |
| ACSL1 | acyl-CoA synthetase long-chain family member 1 |
| ADD3 | adducin 3 (gamma) |
| ADGRG2 | adhesion G protein-coupled receptor G2 |
| ADRB2 | adrenoceptor beta 2, surface |
| AKAP8L | A kinase (PRKA) anchor protein 8-like |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) |
| AKR1C1 | aldo-keto reductase family 1, member C1 |
| AKR1C2 | aldo-keto reductase family 1, member C2 |
| AKR1C3 | aldo-keto reductase family 1, member C3 |
| ALDH3A2 | aldehyde dehydrogenase 3 family, member A2 |
| ARMCX1 | armadillo repeat containing, X-linked 1 |
| ATF5 | activating transcription factor 5 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide |
| AURKA | aurora kinase A |
| AUTS2 | autism susceptibility candidate 2 |
| B3GNT1 | |
| BAG3 | BCL2-associated athanogene 3 |
| BANK1 | B-cell scaffold protein with ankyrin repeats 1 |
| BEX1 | brain expressed, X-linked 1 |
| BLNK | B-cell linker |
| BRD2 | bromodomain containing 2 |
| C1ORF54 | chromosome 1 open reading frame 54 |
| C1QA | complement component 1, q subcomponent, A chain |
| C1QB | complement component 1, q subcomponent, B chain |
| CA12 | carbonic anhydrase XII |
| CBR3 | carbonyl reductase 3 |
| CDK19 | cyclin-dependent kinase 19 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) |
| CHN1 | chimerin 1 |
| CLIC2 | chloride intracellular channel 2 |
| CLU | clusterin |
| COL1A2 | collagen, type I, alpha 2 |
| COL3A1 | collagen, type III, alpha 1 |
| COL6A3 | collagen, type VI, alpha 3 |
| CPE | carboxypeptidase E |
| CRYAB | crystallin, alpha B |
| CST3 | cystatin C |
| CTSL | cathepsin L |
| CXCL13 | chemokine (C-X-C motif) ligand 13 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 |
| CYP4F3 | cytochrome P450, family 4, subfamily F, polypeptide 3 |
| DDX10 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 |
| DEFB1 | defensin, beta 1 |
| DENND1B | DENN/MADD domain containing 1B |
| DLK1 | delta-like 1 homolog (Drosophila) |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
| DNTTIP2 | deoxynucleotidyltransferase, terminal, interacting protein 2 |
| EGF | epidermal growth factor |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 |
| ENPP4 | ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative) |
| EPCAM | epithelial cell adhesion molecule |
| EPHX1 | epoxide hydrolase 1, microsomal (xenobiotic) |
| FAM162A | family with sequence similarity 162, member A |
| FAM20B | family with sequence similarity 20, member B |
| FASTKD5 | FAST kinase domains 5 |
| FGF13 | fibroblast growth factor 13 |
| FOLR1 | folate receptor 1 (adult) |
| FTH1 | ferritin, heavy polypeptide 1 |
| GABARAPL1 | GABA(A) receptor-associated protein like 1 |
| GALC | galactosylceramidase |
| GCLC | glutamate-cysteine ligase, catalytic subunit |
| GDF15 | growth differentiation factor 15 |
| GHITM | growth hormone inducible transmembrane protein |
| GLUL | glutamate-ammonia ligase |
| GOLGA7 | golgin A7 |
| GPC3 | glypican 3 |
| GPM6B | glycoprotein M6B |
| GPNMB | glycoprotein (transmembrane) nmb |
| GPR37 | G protein-coupled receptor 37 (endothelin receptor type B-like) |
| GPX2 | glutathione peroxidase 2 |
| GPX3 | glutathione peroxidase 3 |
| GPX7 | glutathione peroxidase 7 |
| HIST1H2AC | histone cluster 1, H2ac |
| HIST1H2BC | histone cluster 1, H2bc |
| HIST1H2BD | histone cluster 1, H2bd |
| HIST1H2BK | histone cluster 1, H2bk |
| HSD11B1 | hydroxysteroid (11-beta) dehydrogenase 1 |
| HSD17B6 | hydroxysteroid (17-beta) dehydrogenase 6 |
| HSPA8 | heat shock 70kDa protein 8 |
| HSPB8 | heat shock 22kDa protein 8 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 |
| IDS | iduronate 2-sulfatase |
| IL1RN | interleukin 1 receptor antagonist |
| JMJD6 | jumonji domain containing 6 |
| KAT6A | K(lysine) acetyltransferase 6A |
| KDM3A | lysine (K)-specific demethylase 3A |
| KLHDC10 | kelch domain containing 10 |
| MBP | myelin basic protein |
| MFAP3L | microfibrillar-associated protein 3-like |
| MME | membrane metallo-endopeptidase |
| MXRA7 | matrix-remodelling associated 7 |
| NAP1L2 | nucleosome assembly protein 1-like 2 |
| NMT1 | N-myristoyltransferase 1 |
| NPTX2 | neuronal pentraxin II |
| NRIP3 | nuclear receptor interacting protein 3 |
| NT5DC2 | 5'-nucleotidase domain containing 2 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I |
| PDZD8 | PDZ domain containing 8 |
| PER2 | period circadian clock 2 |
| PLIN2 | perilipin 2 |
| PLK1 | polo-like kinase 1 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 |
| PNMAL1 | paraneoplastic Ma antigen family-like 1 |
| PPAP2B | phosphatidic acid phosphatase type 2B |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) |
| PTN | pleiotrophin |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 |
| RYBP | RING1 and YY1 binding protein |
| S100A8 | S100 calcium binding protein A8 |
| SCGB1D2 | secretoglobin, family 1D, member 2 |
| SCGB2A1 | secretoglobin, family 2A, member 1 |
| SCGB2A2 | secretoglobin, family 2A, member 2 |
| SEPP1 | selenoprotein P, plasma, 1 |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 |
| SERPINI1 | serpin peptidase inhibitor, clade I (neuroserpin), member 1 |
| SH3BP5 | SH3-domain binding protein 5 (BTK-associated) |
| SIK1 | salt-inducible kinase 1 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 |
| SLC2A10 | solute carrier family 2 (facilitated glucose transporter), member 10 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SLIT2 | slit homolog 2 (Drosophila) |
| SMAD3 | SMAD family member 3 |
| SPARCL1 | SPARC-like 1 (hevin) |
| STK17A | serine/threonine kinase 17a |
| STK39 | serine threonine kinase 39 |
| TARP | TCR gamma alternate reading frame protein |
| THUMPD1 | THUMP domain containing 1 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 |
| TMCO1 | transmembrane and coiled-coil domains 1 |
| TMEM45A | transmembrane protein 45A |
| TOB1 | transducer of ERBB2, 1 |
| TOMM70A | translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae) |
| TRAK2 | trafficking protein, kinesin binding 2 |
| TUFT1 | tuftelin 1 |
| TWIST1 | twist family bHLH transcription factor 1 |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) |
| UFM1 | ubiquitin-fold modifier 1 |
| UGDH | UDP-glucose 6-dehydrogenase |
| USP14 | ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) |
| VCAM1 | vascular cell adhesion molecule 1 |
| XIST | X inactive specific transcript (non-protein coding) |
| ZNF331 | zinc finger protein 331 |
| Symbol | Name |
|---|---|
| ACD | adrenocortical dysplasia homolog (mouse) |
| ACOT9 | acyl-CoA thioesterase 9 |
| ACTN1 | actinin, alpha 1 |
| ADGRG1 | adhesion G protein-coupled receptor G1 |
| ADGRG6 | adhesion G protein-coupled receptor G6 |
| AEBP1 | AE binding protein 1 |
| AGR2 | anterior gradient 2 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 |
| AMDHD2 | amidohydrolase domain containing 2 |
| ANXA3 | annexin A3 |
| AREG | amphiregulin |
| C3 | complement component 3 |
| CAD | carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase |
| CAPN1 | calpain 1, (mu/I) large subunit |
| CD200 | CD200 molecule |
| CD24 | CD24 molecule |
| CD36 | CD36 molecule (thrombospondin receptor) |
| CD9 | CD9 molecule |
| CDC45 | cell division cycle 45 |
| CDK4 | cyclin-dependent kinase 4 |
| CEBPD | CCAAT/enhancer binding protein (C/EBP), delta |
| CHGB | chromogranin B |
| COL9A3 | collagen, type IX, alpha 3 |
| CTGF | connective tissue growth factor |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| CYR61 | cysteine-rich, angiogenic inducer, 61 |
| DAAM1 | dishevelled associated activator of morphogenesis 1 |
| DHFR | dihydrofolate reductase |
| DMD | dystrophin |
| DPYSL3 | dihydropyrimidinase-like 3 |
| DSP | desmoplakin |
| DUSP1 | dual specificity phosphatase 1 |
| EGFR | epidermal growth factor receptor |
| ETHE1 | ethylmalonic encephalopathy 1 |
| FABP4 | fatty acid binding protein 4, adipocyte |
| FAM216A | family with sequence similarity 216, member A |
| FHL2 | four and a half LIM domains 2 |
| FLNA | filamin A, alpha |
| FOXF2 | forkhead box F2 |
| FXYD5 | FXYD domain containing ion transport regulator 5 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha |
| GALE | UDP-galactose-4-epimerase |
| GATA3 | GATA binding protein 3 |
| GFOD1 | glucose-fructose oxidoreductase domain containing 1 |
| GSN | gelsolin |
| HDAC9 | histone deacetylase 9 |
| HEG1 | heart development protein with EGF-like domains 1 |
| HMOX1 | heme oxygenase 1 |
| HN1 | hematological and neurological expressed 1 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein |
| IER3 | immediate early response 3 |
| IGFBP6 | insulin-like growth factor binding protein 6 |
| IGHM | immunoglobulin heavy constant mu |
| IGKC | immunoglobulin kappa constant |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon |
| INHBA | inhibin, beta A |
| ISG15 | ISG15 ubiquitin-like modifier |
| ITGA6 | integrin, alpha 6 |
| ITGB4 | integrin, beta 4 |
| ITM2A | integral membrane protein 2A |
| JUN | jun proto-oncogene |
| JUNB | jun B proto-oncogene |
| KCTD12 | potassium channel tetramerization domain containing 12 |
| KIAA0125 | KIAA0125 |
| KRT19 | keratin 19, type I |
| L1CAM | L1 cell adhesion molecule |
| LGALS3 | lectin, galactoside-binding, soluble, 3 |
| LMCD1 | LIM and cysteine-rich domains 1 |
| LPL | lipoprotein lipase |
| LTF | lactotransferrin |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MAGEA3 | melanoma antigen family A3 |
| MAGEA6 | melanoma antigen family A6 |
| MARCKSL1 | MARCKS-like 1 |
| MBNL2 | muscleblind-like splicing regulator 2 |
| MCM4 | minichromosome maintenance complex component 4 |
| MCM6 | minichromosome maintenance complex component 6 |
| MGP | matrix Gla protein |
| MSRA | methionine sulfoxide reductase A |
| MTUS1 | microtubule associated tumor suppressor 1 |
| MVP | major vault protein |
| MX1 | MX dynamin-like GTPase 1 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog |
| MYH11 | myosin, heavy chain 11, smooth muscle |
| MYOF | myoferlin |
| NES | nestin |
| NFIB | nuclear factor I/B |
| NID1 | nidogen 1 |
| NRIP1 | nuclear receptor interacting protein 1 |
| NRN1 | neuritin 1 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa |
| OAT | ornithine aminotransferase |
| OLFML2A | olfactomedin-like 2A |
| PAFAH1B3 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) |
| PALLD | palladin, cytoskeletal associated protein |
| PIEZO1 | piezo-type mechanosensitive ion channel component 1 |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PLS3 | plastin 3 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 |
| PNP | purine nucleoside phosphorylase |
| PPARG | peroxisome proliferator-activated receptor gamma |
| PRIM1 | primase, DNA, polypeptide 1 (49kDa) |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta |
| PRKCD | protein kinase C, delta |
| PRSS2 | protease, serine, 2 (trypsin 2) |
| PSIP1 | PC4 and SFRS1 interacting protein 1 |
| PSMB9 | proteasome (prosome, macropain) subunit, beta type, 9 |
| PSPH | phosphoserine phosphatase |
| PTRF | polymerase I and transcript release factor |
| RAB31 | RAB31, member RAS oncogene family |
| RBPMS | RNA binding protein with multiple splicing |
| RFX5 | regulatory factor X, 5 (influences HLA class II expression) |
| RHOB | ras homolog family member B |
| RRAS2 | related RAS viral (r-ras) oncogene homolog 2 |
| S100A11 | S100 calcium binding protein A11 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 |
| SERPINB6 | serpin peptidase inhibitor, clade B (ovalbumin), member 6 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 |
| SFRP4 | secreted frizzled-related protein 4 |
| SLC5A6 | solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 |
| SNAI2 | snail family zinc finger 2 |
| SRI | sorcin |
| SRSF1 | serine/arginine-rich splicing factor 1 |
| SVIL | supervillin |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 |
| TAX1BP3 | Tax1 (human T-cell leukemia virus type I) binding protein 3 |
| TFPI2 | tissue factor pathway inhibitor 2 |
| THBS1 | thrombospondin 1 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase |
| TKTL1 | transketolase-like 1 |
| TM4SF1 | transmembrane 4 L six family member 1 |
| TOX3 | TOX high mobility group box family member 3 |
| TP53I3 | tumor protein p53 inducible protein 3 |
| TPM1 | tropomyosin 1 (alpha) |
| TPM2 | tropomyosin 2 (beta) |
| TRIM2 | tripartite motif containing 2 |
| TUBB6 | tubulin, beta 6 class V |
| UNG | uracil-DNA glycosylase |
| VCAN | versican |
| YWHAH | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta |
| ZEB2 | zinc finger E-box binding homeobox 2 |
| ZFPM2 | zinc finger protein, FOG family member 2 |
