Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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148 genes differentially expressed following the BRD-A39996500_radicicol_HS578T_3_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
AKR1C1 | aldo-keto reductase family 1, member C1 |
AKR1C2 | aldo-keto reductase family 1, member C2 |
AQP3 | aquaporin 3 (Gill blood group) |
AQP9 | aquaporin 9 |
ATP6V0E2 | ATPase, H+ transporting V0 subunit e2 |
AXIN1 | axin 1 |
BAG3 | BCL2-associated athanogene 3 |
CACYBP | calcyclin binding protein |
CASP7 | caspase 7, apoptosis-related cysteine peptidase |
CECR1 | cat eye syndrome chromosome region, candidate 1 |
CES1 | carboxylesterase 1 |
CFB | complement factor B |
CHORDC1 | cysteine and histidine-rich domain (CHORD) containing 1 |
CLDN10 | claudin 10 |
CLU | clusterin |
CXCL13 | chemokine (C-X-C motif) ligand 13 |
DDIT4 | DNA-damage-inducible transcript 4 |
DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 |
DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 |
DNAJB4 | DnaJ (Hsp40) homolog, subfamily B, member 4 |
EFEMP1 | EGF containing fibulin-like extracellular matrix protein 1 |
EYA2 | EYA transcriptional coactivator and phosphatase 2 |
FASN | fatty acid synthase |
FBP1 | fructose-1,6-bisphosphatase 1 |
FCHO1 | FCH domain only 1 |
FCN1 | ficolin (collagen/fibrinogen domain containing) 1 |
FLRT3 | fibronectin leucine rich transmembrane protein 3 |
GJA1 | gap junction protein, alpha 1, 43kDa |
HEBP1 | heme binding protein 1 |
HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
HMOX1 | heme oxygenase 1 |
HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 |
HSPA1A | heat shock 70kDa protein 1A |
HSPA2 | heat shock 70kDa protein 2 |
HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
HSPA8 | heat shock 70kDa protein 8 |
HSPD1 | heat shock 60kDa protein 1 (chaperonin) |
HSPE1 | heat shock 10kDa protein 1 |
HSPH1 | heat shock 105kDa/110kDa protein 1 |
IGKC | immunoglobulin kappa constant |
IGL | immunoglobulin lambda locus |
JMJD6 | jumonji domain containing 6 |
LIMCH1 | LIM and calponin homology domains 1 |
LYZ | lysozyme |
MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 |
MMP12 | matrix metallopeptidase 12 |
MMP7 | matrix metallopeptidase 7 |
NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
NEBL | nebulette |
NEFM | neurofilament, medium polypeptide |
NOTCH1 | notch 1 |
NRIP3 | nuclear receptor interacting protein 3 |
PIR | pirin (iron-binding nuclear protein) |
PLBD1 | phospholipase B domain containing 1 |
PPBP | pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) |
PTGER4 | prostaglandin E receptor 4 (subtype EP4) |
PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 |
RGS1 | regulator of G-protein signaling 1 |
RGS2 | regulator of G-protein signaling 2 |
RGS4 | regulator of G-protein signaling 4 |
RPS11 | ribosomal protein S11 |
SAT1 | spermidine/spermine N1-acetyltransferase 1 |
SFTPA2 | surfactant protein A2 |
SFTPB | surfactant protein B |
SFTPC | surfactant protein C |
SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 |
SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
SPR | sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) |
TLR4 | toll-like receptor 4 |
TRD | T cell receptor delta locus |
TREM1 | triggering receptor expressed on myeloid cells 1 |
TSPYL5 | TSPY-like 5 |
TUSC3 | tumor suppressor candidate 3 |
VCAM1 | vascular cell adhesion molecule 1 |
WDR7 | WD repeat domain 7 |
Symbol | Name |
---|---|
ANXA3 | annexin A3 |
APOD | apolipoprotein D |
AREG | amphiregulin |
ARG1 | arginase 1 |
ARL4C | ADP-ribosylation factor-like 4C |
AZGP1 | alpha-2-glycoprotein 1, zinc-binding |
BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 |
CASP10 | caspase 10, apoptosis-related cysteine peptidase |
CCND2 | cyclin D2 |
CREB1 | cAMP responsive element binding protein 1 |
DKK1 | dickkopf WNT signaling pathway inhibitor 1 |
DPP4 | dipeptidyl-peptidase 4 |
DPT | dermatopontin |
ECM1 | extracellular matrix protein 1 |
EDN1 | endothelin 1 |
EREG | epiregulin |
F2RL1 | coagulation factor II (thrombin) receptor-like 1 |
FBN1 | fibrillin 1 |
FOSL1 | FOS-like antigen 1 |
FST | follistatin |
GALNT3 | polypeptide N-acetylgalactosaminyltransferase 3 |
GNG11 | guanine nucleotide binding protein (G protein), gamma 11 |
GPM6A | glycoprotein M6A |
GPRC5B | G protein-coupled receptor, class C, group 5, member B |
GPX1 | glutathione peroxidase 1 |
HDAC9 | histone deacetylase 9 |
HES1 | hes family bHLH transcription factor 1 |
HOXA5 | homeobox A5 |
ID4 | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein |
IER3 | immediate early response 3 |
IFI16 | interferon, gamma-inducible protein 16 |
IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 |
KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 |
KRT23 | keratin 23, type I |
LAMA3 | laminin, alpha 3 |
MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
MFAP5 | microfibrillar associated protein 5 |
MGLL | monoglyceride lipase |
MGP | matrix Gla protein |
MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 |
NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
NRN1 | neuritin 1 |
NT5E | 5'-nucleotidase, ecto (CD73) |
OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa |
OXTR | oxytocin receptor |
PCNA | proliferating cell nuclear antigen |
PDGFC | platelet derived growth factor C |
PERP | PERP, TP53 apoptosis effector |
PSPH | phosphoserine phosphatase |
PTGDS | prostaglandin D2 synthase 21kDa (brain) |
RHOBTB3 | Rho-related BTB domain containing 3 |
RRAS2 | related RAS viral (r-ras) oncogene homolog 2 |
S100P | S100 calcium binding protein P |
SFRP1 | secreted frizzled-related protein 1 |
SRPX | sushi-repeat containing protein, X-linked |
ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 |
TF | transferrin |
TFPI2 | tissue factor pathway inhibitor 2 |
THBS2 | thrombospondin 2 |
TIPARP | TCDD-inducible poly(ADP-ribose) polymerase |
TMEM158 | transmembrane protein 158 (gene/pseudogene) |
TSPAN8 | tetraspanin 8 |
TXNIP | thioredoxin interacting protein |
UGCG | UDP-glucose ceramide glucosyltransferase |
VCAN | versican |
VGLL4 | vestigial-like family member 4 |
WASF3 | WAS protein family, member 3 |
WT1 | Wilms tumor 1 |
WWTR1 | WW domain containing transcription regulator 1 |