BRD-A39996500_radicicol_LNCAP_3_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

77 genes differentially expressed following the BRD-A39996500_radicicol_LNCAP_3_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADIRF adipogenesis regulatory factor
ANXA6 annexin A6
CD27 CD27 molecule
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHORDC1 cysteine and histidine-rich domain (CHORD) containing 1
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
COBL cordon-bleu WH2 repeat protein
CTGF connective tissue growth factor
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DUSP2 dual specificity phosphatase 2
EGR1 early growth response 1
EIF5A eukaryotic translation initiation factor 5A
EPS8 epidermal growth factor receptor pathway substrate 8
FKBP11 FK506 binding protein 11, 19 kDa
GPER1 G protein-coupled estrogen receptor 1
GPM6B glycoprotein M6B
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HMOX1 heme oxygenase 1
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
HSPA13 heat shock protein 70kDa family, member 13
HSPA1A heat shock 70kDa protein 1A
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPB8 heat shock 22kDa protein 8
HSPH1 heat shock 105kDa/110kDa protein 1
IGKV1-5 immunoglobulin kappa variable 1-5
JMJD6 jumonji domain containing 6
MATN2 matrilin 2
MEF2C myocyte enhancer factor 2C
MSLN mesothelin
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NPR3 natriuretic peptide receptor 3
NUPR1 nuclear protein, transcriptional regulator, 1
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
SCRG1 stimulator of chondrogenesis 1
SDF2L1 stromal cell-derived factor 2-like 1
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SLC16A7 solute carrier family 16 (monocarboxylate transporter), member 7
VCAM1 vascular cell adhesion molecule 1
VEGFA vascular endothelial growth factor A

decreased expression

Symbol Name
ADI1 acireductone dioxygenase 1
APOA1 apolipoprotein A-I
APOH apolipoprotein H (beta-2-glycoprotein I)
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BEX1 brain expressed, X-linked 1
CADM1 cell adhesion molecule 1
CCNB1 cyclin B1
CD36 CD36 molecule (thrombospondin receptor)
COL4A5 collagen, type IV, alpha 5
CPS1 carbamoyl-phosphate synthase 1, mitochondrial
CST1 cystatin SN
CYB5A cytochrome b5 type A (microsomal)
DHRS2 dehydrogenase/reductase (SDR family) member 2
EIF5 eukaryotic translation initiation factor 5
F3 coagulation factor III (thromboplastin, tissue factor)
FGB fibrinogen beta chain
FGG fibrinogen gamma chain
GAL galanin/GMAP prepropeptide
GRB7 growth factor receptor-bound protein 7
IGSF3 immunoglobulin superfamily, member 3
JADE2 jade family PHD finger 2
KLF9 Kruppel-like factor 9
KYNU kynureninase
LPL lipoprotein lipase
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
SESN1 sestrin 1
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
TM4SF1 transmembrane 4 L six family member 1
TOX3 TOX high mobility group box family member 3
TYRP1 tyrosinase-related protein 1
Funding