| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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220 genes differentially expressed following the BRD-A39996500_radicicol_SKBR3_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ABLIM1 | actin binding LIM protein 1 |
| ACSM3 | acyl-CoA synthetase medium-chain family member 3 |
| ADGRG6 | adhesion G protein-coupled receptor G6 |
| AHCYL1 | adenosylhomocysteinase-like 1 |
| AHSA1 | AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast) |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 |
| AMFR | autocrine motility factor receptor, E3 ubiquitin protein ligase |
| ARFIP2 | ADP-ribosylation factor interacting protein 2 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding |
| BAG3 | BCL2-associated athanogene 3 |
| BAZ2B | bromodomain adjacent to zinc finger domain, 2B |
| BCL6 | B-cell CLL/lymphoma 6 |
| BEX4 | brain expressed, X-linked 4 |
| CALCA | calcitonin-related polypeptide alpha |
| CAPN6 | calpain 6 |
| CCNG1 | cyclin G1 |
| CCNG2 | cyclin G2 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) |
| CDK19 | cyclin-dependent kinase 19 |
| CFB | complement factor B |
| COL2A1 | collagen, type II, alpha 1 |
| CORO1B | coronin, actin binding protein, 1B |
| CRYZ | crystallin, zeta (quinone reductase) |
| CTSH | cathepsin H |
| CTSZ | cathepsin Z |
| DLK1 | delta-like 1 homolog (Drosophila) |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 |
| DPP4 | dipeptidyl-peptidase 4 |
| ECHDC2 | enoyl CoA hydratase domain containing 2 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 |
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 |
| ERBB3 | erb-b2 receptor tyrosine kinase 3 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 |
| GAS1 | growth arrest-specific 1 |
| GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) |
| GLS | glutaminase |
| GPATCH8 | G patch domain containing 8 |
| GRSF1 | G-rich RNA sequence binding factor 1 |
| GSTM3 | glutathione S-transferase mu 3 (brain) |
| GSTT1 | glutathione S-transferase theta 1 |
| HIST3H2A | histone cluster 3, H2a |
| HNMT | histamine N-methyltransferase |
| HSPA1A | heat shock 70kDa protein 1A |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) |
| IFITM1 | interferon induced transmembrane protein 1 |
| ITGA6 | integrin, alpha 6 |
| KLK11 | kallikrein-related peptidase 11 |
| MAN2A1 | mannosidase, alpha, class 2A, member 1 |
| MDFIC | MyoD family inhibitor domain containing |
| MOAP1 | modulator of apoptosis 1 |
| MSLN | mesothelin |
| MUC4 | mucin 4, cell surface associated |
| MVP | major vault protein |
| MYBPC1 | myosin binding protein C, slow type |
| MYL1 | myosin, light chain 1, alkali; skeletal, fast |
| MYO5C | myosin VC |
| N4BP2L2 | NEDD4 binding protein 2-like 2 |
| NBR1 | neighbor of BRCA1 gene 1 |
| NEBL | nebulette |
| NIPSNAP1 | nipsnap homolog 1 (C. elegans) |
| OBSL1 | obscurin-like 1 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide |
| PCMTD2 | protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2 |
| PDCD4 | programmed cell death 4 (neoplastic transformation inhibitor) |
| PDZK1IP1 | PDZK1 interacting protein 1 |
| PHACTR2 | phosphatase and actin regulator 2 |
| PLAGL1 | pleiomorphic adenoma gene-like 1 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
| RHOBTB3 | Rho-related BTB domain containing 3 |
| RPL22 | ribosomal protein L22 |
| RPL31 | ribosomal protein L31 |
| RSL1D1 | ribosomal L1 domain containing 1 |
| S100A10 | S100 calcium binding protein A10 |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit |
| SCRN1 | secernin 1 |
| SFTPB | surfactant protein B |
| SFTPC | surfactant protein C |
| SH3BP4 | SH3-domain binding protein 4 |
| SH3YL1 | SH3 and SYLF domain containing 1 |
| SLC19A2 | solute carrier family 19 (thiamine transporter), member 2 |
| SLC2A10 | solute carrier family 2 (facilitated glucose transporter), member 10 |
| SLC34A2 | solute carrier family 34 (type II sodium/phosphate cotransporter), member 2 |
| SLC38A1 | solute carrier family 38, member 1 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 |
| SPAG16 | sperm associated antigen 16 |
| SPATA20 | spermatogenesis associated 20 |
| STAT6 | signal transducer and activator of transcription 6, interleukin-4 induced |
| TBC1D9B | TBC1 domain family, member 9B (with GRAM domain) |
| TFRC | transferrin receptor |
| TGFBR3 | transforming growth factor, beta receptor III |
| TGM2 | transglutaminase 2 |
| TMEM5 | transmembrane protein 5 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 |
| TNNC1 | troponin C type 1 (slow) |
| TOB1 | transducer of ERBB2, 1 |
| TPD52L1 | tumor protein D52-like 1 |
| TRIB2 | tribbles pseudokinase 2 |
| TST | thiosulfate sulfurtransferase (rhodanese) |
| TUG1 | taurine up-regulated 1 (non-protein coding) |
| VAMP8 | vesicle-associated membrane protein 8 |
| WSCD1 | WSC domain containing 1 |
| XBP1 | X-box binding protein 1 |
| ZBTB18 | zinc finger and BTB domain containing 18 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 |
| ZMYM2 | zinc finger, MYM-type 2 |
| Symbol | Name |
|---|---|
| ACAT2 | acetyl-CoA acetyltransferase 2 |
| ACOT7 | acyl-CoA thioesterase 7 |
| ACTG2 | actin, gamma 2, smooth muscle, enteric |
| ADD3 | adducin 3 (gamma) |
| AEBP1 | AE binding protein 1 |
| AKAP12 | A kinase (PRKA) anchor protein 12 |
| AQP3 | aquaporin 3 (Gill blood group) |
| AREG | amphiregulin |
| BGN | biglycan |
| BIRC2 | baculoviral IAP repeat containing 2 |
| C1ORF61 | chromosome 1 open reading frame 61 |
| CA12 | carbonic anhydrase XII |
| CA2 | carbonic anhydrase II |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) |
| CCL2 | chemokine (C-C motif) ligand 2 |
| CCNE2 | cyclin E2 |
| CD52 | CD52 molecule |
| CD58 | CD58 molecule |
| CDC45 | cell division cycle 45 |
| CDC6 | cell division cycle 6 |
| CDK1 | cyclin-dependent kinase 1 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 |
| CKAP4 | cytoskeleton-associated protein 4 |
| CLTB | clathrin, light chain B |
| COL14A1 | collagen, type XIV, alpha 1 |
| CORO1A | coronin, actin binding protein, 1A |
| CSRP1 | cysteine and glycine-rich protein 1 |
| CSTA | cystatin A (stefin A) |
| CXCL14 | chemokine (C-X-C motif) ligand 14 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| DCK | deoxycytidine kinase |
| DCLK1 | doublecortin-like kinase 1 |
| DHFR | dihydrofolate reductase |
| DPYSL2 | dihydropyrimidinase-like 2 |
| DUSP4 | dual specificity phosphatase 4 |
| EGR2 | early growth response 2 |
| EGR3 | early growth response 3 |
| EIF5 | eukaryotic translation initiation factor 5 |
| EIF5A | eukaryotic translation initiation factor 5A |
| ENO2 | enolase 2 (gamma, neuronal) |
| EPHA3 | EPH receptor A3 |
| FCGBP | Fc fragment of IgG binding protein |
| FOS | FBJ murine osteosarcoma viral oncogene homolog |
| FOXG1 | forkhead box G1 |
| FXYD6 | FXYD domain containing ion transport regulator 6 |
| GAL | galanin/GMAP prepropeptide |
| GFOD1 | glucose-fructose oxidoreductase domain containing 1 |
| GGH | gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) |
| GINS1 | GINS complex subunit 1 (Psf1 homolog) |
| GINS2 | GINS complex subunit 2 (Psf2 homolog) |
| GNAS | GNAS complex locus |
| GPM6A | glycoprotein M6A |
| HOXA10 | homeobox A10 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein |
| IGHD | immunoglobulin heavy constant delta |
| IGHM | immunoglobulin heavy constant mu |
| IGKC | immunoglobulin kappa constant |
| IGL | immunoglobulin lambda locus |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon |
| IL2RG | interleukin 2 receptor, gamma |
| IL32 | interleukin 32 |
| INSIG1 | insulin induced gene 1 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) |
| JADE2 | jade family PHD finger 2 |
| JAG1 | jagged 1 |
| KLF4 | Kruppel-like factor 4 (gut) |
| KRT14 | keratin 14, type I |
| KRT15 | keratin 15, type I |
| KRT6B | keratin 6B, type II |
| LINC00341 | long intergenic non-protein coding RNA 341 |
| LMO3 | LIM domain only 3 (rhombotin-like 2) |
| LRRC17 | leucine rich repeat containing 17 |
| LTF | lactotransferrin |
| MARCKS | myristoylated alanine-rich protein kinase C substrate |
| MELK | maternal embryonic leucine zipper kinase |
| MMP9 | matrix metallopeptidase 9 |
| MYBL2 | v-myb avian myeloblastosis viral oncogene homolog-like 2 |
| MYH11 | myosin, heavy chain 11, smooth muscle |
| MYLK | myosin light chain kinase |
| NAV3 | neuron navigator 3 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 |
| OLFM4 | olfactomedin 4 |
| PDE2A | phosphodiesterase 2A, cGMP-stimulated |
| PNMA2 | paraneoplastic Ma antigen 2 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit |
| PPAP2B | phosphatidic acid phosphatase type 2B |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta |
| PRKCB | protein kinase C, beta |
| PTN | pleiotrophin |
| PYCR1 | pyrroline-5-carboxylate reductase 1 |
| RFTN1 | raftlin, lipid raft linker 1 |
| RRM2 | ribonucleotide reductase M2 |
| RTN1 | reticulon 1 |
| SDF2L1 | stromal cell-derived factor 2-like 1 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 |
| SLC2A5 | solute carrier family 2 (facilitated glucose/fructose transporter), member 5 |
| SNAP25 | synaptosomal-associated protein, 25kDa |
| SPINK2 | serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) |
| SYNM | synemin, intermediate filament protein |
| SYT1 | synaptotagmin I |
| TAGLN | transgelin |
| THBS2 | thrombospondin 2 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 |
| TRIB3 | tribbles pseudokinase 3 |
| TRMT5 | tRNA methyltransferase 5 |
| TUBB2A | tubulin, beta 2A class IIa |
| TUBB4B | tubulin, beta 4B class IVb |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) |
| ZFP36L2 | ZFP36 ring finger protein-like 2 |
