| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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271 genes differentially expressed following the BRD-A45498368_WYE-125132_A549_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 |
| ABCG1 | ATP-binding cassette, sub-family G (WHITE), member 1 |
| ABLIM1 | actin binding LIM protein 1 |
| AGR2 | anterior gradient 2 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 |
| ALDH5A1 | aldehyde dehydrogenase 5 family, member A1 |
| AMDHD2 | amidohydrolase domain containing 2 |
| ANXA4 | annexin A4 |
| AREG | amphiregulin |
| ASAH1 | N-acylsphingosine amidohydrolase (acid ceramidase) 1 |
| ATP9A | ATPase, class II, type 9A |
| BEX1 | brain expressed, X-linked 1 |
| BTF3 | basic transcription factor 3 |
| C6ORF48 | chromosome 6 open reading frame 48 |
| C6ORF62 | chromosome 6 open reading frame 62 |
| CAMLG | calcium modulating ligand |
| CAV2 | caveolin 2 |
| CCNG2 | cyclin G2 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha |
| CIRBP | cold inducible RNA binding protein |
| CST1 | cystatin SN |
| CTSA | cathepsin A |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| DOCK9 | dedicator of cytokinesis 9 |
| DUSP4 | dual specificity phosphatase 4 |
| EGFR | epidermal growth factor receptor |
| EIF3D | eukaryotic translation initiation factor 3, subunit D |
| EIF3E | eukaryotic translation initiation factor 3, subunit E |
| EIF3M | eukaryotic translation initiation factor 3, subunit M |
| EIF4B | eukaryotic translation initiation factor 4B |
| EPAS1 | endothelial PAS domain protein 1 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 |
| FAM63A | family with sequence similarity 63, member A |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B |
| FOSL2 | FOS-like antigen 2 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 |
| GALC | galactosylceramidase |
| GATAD1 | GATA zinc finger domain containing 1 |
| GLTSCR2 | glioma tumor suppressor candidate region gene 2 |
| GOLGA8A | golgin A8 family, member A |
| GOLGA8H | golgin A8 family, member H |
| GPR137B | G protein-coupled receptor 137B |
| GRN | granulin |
| GSE1 | Gse1 coiled-coil protein |
| HEBP1 | heme binding protein 1 |
| HIST3H2A | histone cluster 3, H2a |
| HLA-E | major histocompatibility complex, class I, E |
| HOPX | HOP homeobox |
| IDS | iduronate 2-sulfatase |
| IGBP1 | immunoglobulin (CD79A) binding protein 1 |
| IGF1R | insulin-like growth factor 1 receptor |
| IL1R1 | interleukin 1 receptor, type I |
| IMPDH2 | IMP (inosine 5'-monophosphate) dehydrogenase 2 |
| IRS1 | insulin receptor substrate 1 |
| IRS2 | insulin receptor substrate 2 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 |
| JADE2 | jade family PHD finger 2 |
| KANK1 | KN motif and ankyrin repeat domains 1 |
| KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 |
| KLF6 | Kruppel-like factor 6 |
| LAMA4 | laminin, alpha 4 |
| LETMD1 | LETM1 domain containing 1 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 |
| LOX | lysyl oxidase |
| LXN | latexin |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MET | MET proto-oncogene, receptor tyrosine kinase |
| MGLL | monoglyceride lipase |
| MNT | MAX network transcriptional repressor |
| MTMR11 | myotubularin related protein 11 |
| MXI1 | MAX interactor 1, dimerization protein |
| MYOF | myoferlin |
| NBEA | neurobeachin |
| NBR1 | neighbor of BRCA1 gene 1 |
| NPTX2 | neuronal pentraxin II |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase |
| ORAI3 | ORAI calcium release-activated calcium modulator 3 |
| PAM | peptidylglycine alpha-amidating monooxygenase |
| PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 |
| PDGFC | platelet derived growth factor C |
| PDLIM5 | PDZ and LIM domain 5 |
| PGLS | 6-phosphogluconolactonase |
| PLCB4 | phospholipase C, beta 4 |
| POLR1D | polymerase (RNA) I polypeptide D, 16kDa |
| PSCA | prostate stem cell antigen |
| PTEN | phosphatase and tensin homolog |
| QARS | glutaminyl-tRNA synthetase |
| QPCT | glutaminyl-peptide cyclotransferase |
| RASGRP1 | RAS guanyl releasing protein 1 (calcium and DAG-regulated) |
| RASSF2 | Ras association (RalGDS/AF-6) domain family member 2 |
| RBKS | ribokinase |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| RGS5 | regulator of G-protein signaling 5 |
| RPL31 | ribosomal protein L31 |
| RPL36 | ribosomal protein L36 |
| RRAGD | Ras-related GTP binding D |
| RSL1D1 | ribosomal L1 domain containing 1 |
| RSRP1 | arginine/serine-rich protein 1 |
| SAMD4A | sterile alpha motif domain containing 4A |
| SATB1 | SATB homeobox 1 |
| SCAMP1 | secretory carrier membrane protein 1 |
| SDPR | serum deprivation response |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 |
| SERPINB6 | serpin peptidase inhibitor, clade B (ovalbumin), member 6 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 |
| SLC16A6 | solute carrier family 16, member 6 |
| SMAD3 | SMAD family member 3 |
| SMYD2 | SET and MYND domain containing 2 |
| SOX4 | SRY (sex determining region Y)-box 4 |
| STC1 | stanniocalcin 1 |
| SULT1C2 | sulfotransferase family, cytosolic, 1C, member 2 |
| TFF1 | trefoil factor 1 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) |
| TFPI2 | tissue factor pathway inhibitor 2 |
| TGM2 | transglutaminase 2 |
| THBS4 | thrombospondin 4 |
| TM4SF1 | transmembrane 4 L six family member 1 |
| TPCN1 | two pore segment channel 1 |
| TPP1 | tripeptidyl peptidase I |
| TRAF5 | TNF receptor-associated factor 5 |
| TRAPPC6A | trafficking protein particle complex 6A |
| TRIB2 | tribbles pseudokinase 2 |
| TRIM8 | tripartite motif containing 8 |
| USE1 | unconventional SNARE in the ER 1 homolog (S. cerevisiae) |
| VAT1 | vesicle amine transport 1 |
| VDAC1 | voltage-dependent anion channel 1 |
| VWF | von Willebrand factor |
| WDR45 | WD repeat domain 45 |
| YPEL5 | yippee-like 5 (Drosophila) |
| ZNF185 | zinc finger protein 185 (LIM domain) |
| ZNF277 | zinc finger protein 277 |
| Symbol | Name |
|---|---|
| AK1 | adenylate kinase 1 |
| AQP3 | aquaporin 3 (Gill blood group) |
| ASF1B | anti-silencing function 1B histone chaperone |
| ATAD2 | ATPase family, AAA domain containing 2 |
| AURKA | aurora kinase A |
| AURKB | aurora kinase B |
| BIRC5 | baculoviral IAP repeat containing 5 |
| BRCA1 | breast cancer 1, early onset |
| BUB1 | BUB1 mitotic checkpoint serine/threonine kinase |
| BUB1B | BUB1 mitotic checkpoint serine/threonine kinase B |
| CA2 | carbonic anhydrase II |
| CALML4 | calmodulin-like 4 |
| CCNA2 | cyclin A2 |
| CCNB2 | cyclin B2 |
| CCND3 | cyclin D3 |
| CCNF | cyclin F |
| CDC20 | cell division cycle 20 |
| CDC25A | cell division cycle 25A |
| CDC6 | cell division cycle 6 |
| CDC7 | cell division cycle 7 |
| CDCA3 | cell division cycle associated 3 |
| CDK1 | cyclin-dependent kinase 1 |
| CDK2 | cyclin-dependent kinase 2 |
| CDKN3 | cyclin-dependent kinase inhibitor 3 |
| CENPA | centromere protein A |
| CENPN | centromere protein N |
| CENPU | centromere protein U |
| CEP55 | centrosomal protein 55kDa |
| CHEK2 | checkpoint kinase 2 |
| CHORDC1 | cysteine and histidine-rich domain (CHORD) containing 1 |
| CKS1B | CDC28 protein kinase regulatory subunit 1B |
| CSRP2 | cysteine and glycine-rich protein 2 |
| CXCL10 | chemokine (C-X-C motif) ligand 10 |
| CXCL13 | chemokine (C-X-C motif) ligand 13 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 |
| DBF4 | DBF4 zinc finger |
| DHCR24 | 24-dehydrocholesterol reductase |
| DHFR | dihydrofolate reductase |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 |
| DSCC1 | DNA replication and sister chromatid cohesion 1 |
| DTL | denticleless E3 ubiquitin protein ligase homolog (Drosophila) |
| EIF4EBP1 | eukaryotic translation initiation factor 4E binding protein 1 |
| EMP2 | epithelial membrane protein 2 |
| FANCI | Fanconi anemia, complementation group I |
| FEN1 | flap structure-specific endonuclease 1 |
| FOXM1 | forkhead box M1 |
| GAL | galanin/GMAP prepropeptide |
| GGH | gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) |
| GINS1 | GINS complex subunit 1 (Psf1 homolog) |
| GINS2 | GINS complex subunit 2 (Psf2 homolog) |
| GPM6B | glycoprotein M6B |
| GTSE1 | G-2 and S-phase expressed 1 |
| H2AFX | H2A histone family, member X |
| H2AFZ | H2A histone family, member Z |
| HAT1 | histone acetyltransferase 1 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
| HMMR | hyaluronan-mediated motility receptor (RHAMM) |
| IDI1 | isopentenyl-diphosphate delta isomerase 1 |
| IGHD | immunoglobulin heavy constant delta |
| IGHM | immunoglobulin heavy constant mu |
| IGKC | immunoglobulin kappa constant |
| IGKV1-5 | immunoglobulin kappa variable 1-5 |
| IGKV4-1 | immunoglobulin kappa variable 4-1 |
| IGL | immunoglobulin lambda locus |
| ITGAE | integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) |
| JCHAIN | joining chain of multimeric IgA and IgM |
| KIF14 | kinesin family member 14 |
| KIF15 | kinesin family member 15 |
| KIF18B | kinesin family member 18B |
| KIF20A | kinesin family member 20A |
| KIF4A | kinesin family member 4A |
| KPNA2 | karyopherin alpha 2 (RAG cohort 1, importin alpha 1) |
| KRT14 | keratin 14, type I |
| KRT5 | keratin 5, type II |
| LAPTM4B | lysosomal protein transmembrane 4 beta |
| LMNB1 | lamin B1 |
| LTF | lactotransferrin |
| MAD2L1 | MAD2 mitotic arrest deficient-like 1 (yeast) |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 |
| MARS | methionyl-tRNA synthetase |
| MCAM | melanoma cell adhesion molecule |
| MCM10 | minichromosome maintenance complex component 10 |
| MCM3 | minichromosome maintenance complex component 3 |
| MCM4 | minichromosome maintenance complex component 4 |
| MCM5 | minichromosome maintenance complex component 5 |
| MCM6 | minichromosome maintenance complex component 6 |
| MFAP4 | microfibrillar-associated protein 4 |
| MSX1 | msh homeobox 1 |
| MYBL2 | v-myb avian myeloblastosis viral oncogene homolog-like 2 |
| MYCBP | MYC binding protein |
| NAT1 | N-acetyltransferase 1 (arylamine N-acetyltransferase) |
| NCAPG | non-SMC condensin I complex, subunit G |
| NCAPG2 | non-SMC condensin II complex, subunit G2 |
| NCAPH | non-SMC condensin I complex, subunit H |
| NDC80 | NDC80 kinetochore complex component |
| OIP5 | Opa interacting protein 5 |
| ORC6 | origin recognition complex, subunit 6 |
| PBK | PDZ binding kinase |
| PCP4 | Purkinje cell protein 4 |
| PEA15 | phosphoprotein enriched in astrocytes 15 |
| PHGDH | phosphoglycerate dehydrogenase |
| PI3 | peptidase inhibitor 3, skin-derived |
| POLA2 | polymerase (DNA directed), alpha 2, accessory subunit |
| PRC1 | protein regulator of cytokinesis 1 |
| PRIM1 | primase, DNA, polypeptide 1 (49kDa) |
| PRKCB | protein kinase C, beta |
| PSAT1 | phosphoserine aminotransferase 1 |
| PSRC1 | proline/serine-rich coiled-coil 1 |
| RAD51C | RAD51 paralog C |
| RFC2 | replication factor C (activator 1) 2, 40kDa |
| RFC3 | replication factor C (activator 1) 3, 38kDa |
| RFC4 | replication factor C (activator 1) 4, 37kDa |
| RFC5 | replication factor C (activator 1) 5, 36.5kDa |
| RPA3 | replication protein A3, 14kDa |
| RPN1 | ribophorin I |
| RRM2 | ribonucleotide reductase M2 |
| S100A9 | S100 calcium binding protein A9 |
| SCGB1D2 | secretoglobin, family 1D, member 2 |
| SCGB2A1 | secretoglobin, family 2A, member 1 |
| SDF2L1 | stromal cell-derived factor 2-like 1 |
| SKP2 | S-phase kinase-associated protein 2, E3 ubiquitin protein ligase |
| SLPI | secretory leukocyte peptidase inhibitor |
| SNRNP25 | small nuclear ribonucleoprotein 25kDa (U11/U12) |
| SUB1 | SUB1 homolog (S. cerevisiae) |
| TFAP2B | transcription factor AP-2 beta (activating enhancer binding protein 2 beta) |
| TIMELESS | timeless circadian clock |
| TK1 | thymidine kinase 1, soluble |
| TMPO | thymopoietin |
| TRIP13 | thyroid hormone receptor interactor 13 |
| TUBG1 | tubulin, gamma 1 |
| UBE2C | ubiquitin-conjugating enzyme E2C |
| VRK1 | vaccinia related kinase 1 |
| YKT6 | YKT6 v-SNARE homolog (S. cerevisiae) |
| YWHAH | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta |
| ZWINT | ZW10 interacting kinetochore protein |
