| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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230 genes differentially expressed following the BRD-A45498368_WYE-125132_BT20_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ABHD4 | abhydrolase domain containing 4 |
| AGTR1 | angiotensin II receptor, type 1 |
| AHNAK2 | AHNAK nucleoprotein 2 |
| ARG1 | arginase 1 |
| ARMCX1 | armadillo repeat containing, X-linked 1 |
| ATP6V1G1 | ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1 |
| BACE2 | beta-site APP-cleaving enzyme 2 |
| BAZ2B | bromodomain adjacent to zinc finger domain, 2B |
| BRD8 | bromodomain containing 8 |
| BTG1 | B-cell translocation gene 1, anti-proliferative |
| C1QA | complement component 1, q subcomponent, A chain |
| C1QB | complement component 1, q subcomponent, B chain |
| CALCOCO1 | calcium binding and coiled-coil domain 1 |
| CAMLG | calcium modulating ligand |
| CBLB | Cbl proto-oncogene B, E3 ubiquitin protein ligase |
| CCNG2 | cyclin G2 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) |
| CD99 | CD99 molecule |
| CDK19 | cyclin-dependent kinase 19 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) |
| CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) |
| COL18A1 | collagen, type XVIII, alpha 1 |
| CSF1R | colony stimulating factor 1 receptor |
| CTSB | cathepsin B |
| CYTH1 | cytohesin 1 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 |
| ECHDC2 | enoyl CoA hydratase domain containing 2 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 |
| EPHB2 | EPH receptor B2 |
| ERBB3 | erb-b2 receptor tyrosine kinase 3 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 |
| F13A1 | coagulation factor XIII, A1 polypeptide |
| FOLR1 | folate receptor 1 (adult) |
| FOXO4 | forkhead box O4 |
| GADD45B | growth arrest and DNA-damage-inducible, beta |
| GAS6 | growth arrest-specific 6 |
| GCC2 | GRIP and coiled-coil domain containing 2 |
| GDF15 | growth differentiation factor 15 |
| GLTSCR2 | glioma tumor suppressor candidate region gene 2 |
| GPR137B | G protein-coupled receptor 137B |
| GRN | granulin |
| GSN | gelsolin |
| H1F0 | H1 histone family, member 0 |
| HBP1 | HMG-box transcription factor 1 |
| HCLS1 | hematopoietic cell-specific Lyn substrate 1 |
| HIST1H2AC | histone cluster 1, H2ac |
| HIST1H2BD | histone cluster 1, H2bd |
| HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 |
| HMOX1 | heme oxygenase 1 |
| HSPA1A | heat shock 70kDa protein 1A |
| IFITM1 | interferon induced transmembrane protein 1 |
| IGFBP7 | insulin-like growth factor binding protein 7 |
| IL6ST | interleukin 6 signal transducer |
| INSR | insulin receptor |
| IRS2 | insulin receptor substrate 2 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 |
| JADE2 | jade family PHD finger 2 |
| JMJD1C | jumonji domain containing 1C |
| KLHDC2 | kelch domain containing 2 |
| KLHL21 | kelch-like family member 21 |
| LAMP2 | lysosomal-associated membrane protein 2 |
| LAPTM5 | lysosomal protein transmembrane 5 |
| LEPROT | leptin receptor overlapping transcript |
| LGALS8 | lectin, galactoside-binding, soluble, 8 |
| LMBRD1 | LMBR1 domain containing 1 |
| LRP10 | low density lipoprotein receptor-related protein 10 |
| LXN | latexin |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 |
| MT1F | metallothionein 1F |
| MT1G | metallothionein 1G |
| MT1H | metallothionein 1H |
| MT1HL1 | metallothionein 1H-like 1 |
| MTSS1 | metastasis suppressor 1 |
| MVP | major vault protein |
| N4BP2L1 | NEDD4 binding protein 2-like 1 |
| NBR1 | neighbor of BRCA1 gene 1 |
| NEBL | nebulette |
| NMRK1 | nicotinamide riboside kinase 1 |
| NOS3 | nitric oxide synthase 3 (endothelial cell) |
| OPTN | optineurin |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 |
| PLXNB2 | plexin B2 |
| PNKP | polynucleotide kinase 3'-phosphatase |
| PPAP2B | phosphatidic acid phosphatase type 2B |
| PSAP | prosaposin |
| RHOBTB3 | Rho-related BTB domain containing 3 |
| RND3 | Rho family GTPase 3 |
| RPS27L | ribosomal protein S27-like |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 |
| RRAGC | Ras-related GTP binding C |
| RTN2 | reticulon 2 |
| SAMSN1 | SAM domain, SH3 domain and nuclear localization signals 1 |
| SEMA4C | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C |
| SEPP1 | selenoprotein P, plasma, 1 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 |
| SLC19A2 | solute carrier family 19 (thiamine transporter), member 2 |
| SMAD3 | SMAD family member 3 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing |
| SOX4 | SRY (sex determining region Y)-box 4 |
| SQSTM1 | sequestosome 1 |
| SRGN | serglycin |
| STAT6 | signal transducer and activator of transcription 6, interleukin-4 induced |
| TGFBI | transforming growth factor, beta-induced, 68kDa |
| TGM2 | transglutaminase 2 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 |
| TMEM59 | transmembrane protein 59 |
| TPP1 | tripeptidyl peptidase I |
| TSPAN4 | tetraspanin 4 |
| TWIST1 | twist family bHLH transcription factor 1 |
| VAT1 | vesicle amine transport 1 |
| VPS13C | vacuolar protein sorting 13 homolog C (S. cerevisiae) |
| WDTC1 | WD and tetratricopeptide repeats 1 |
| YPEL5 | yippee-like 5 (Drosophila) |
| Symbol | Name |
|---|---|
| ACAT2 | acetyl-CoA acetyltransferase 2 |
| AGR2 | anterior gradient 2 |
| AK2 | adenylate kinase 2 |
| AK4 | adenylate kinase 4 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) |
| AKR1C1 | aldo-keto reductase family 1, member C1 |
| AKR1C2 | aldo-keto reductase family 1, member C2 |
| AKR1C3 | aldo-keto reductase family 1, member C3 |
| AMMECR1 | Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1 |
| BAMBI | BMP and activin membrane-bound inhibitor |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 |
| BZW2 | basic leucine zipper and W2 domains 2 |
| CA12 | carbonic anhydrase XII |
| CA2 | carbonic anhydrase II |
| CCT2 | chaperonin containing TCP1, subunit 2 (beta) |
| CD36 | CD36 molecule (thrombospondin receptor) |
| CDC25A | cell division cycle 25A |
| CDC45 | cell division cycle 45 |
| CDC6 | cell division cycle 6 |
| CRLF1 | cytokine receptor-like factor 1 |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) |
| CSTA | cystatin A (stefin A) |
| CYB561 | cytochrome b561 |
| CYB5A | cytochrome b5 type A (microsomal) |
| CYCS | cytochrome c, somatic |
| DLD | dihydrolipoamide dehydrogenase |
| DTL | denticleless E3 ubiquitin protein ligase homolog (Drosophila) |
| EBP | emopamil binding protein (sterol isomerase) |
| ENAH | enabled homolog (Drosophila) |
| ENO1 | enolase 1, (alpha) |
| FABP4 | fatty acid binding protein 4, adipocyte |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) |
| FAH | fumarylacetoacetate hydrolase (fumarylacetoacetase) |
| FAM57A | family with sequence similarity 57, member A |
| FEN1 | flap structure-specific endonuclease 1 |
| GAL | galanin/GMAP prepropeptide |
| GALNT3 | polypeptide N-acetylgalactosaminyltransferase 3 |
| GGCT | gamma-glutamylcyclotransferase |
| GINS1 | GINS complex subunit 1 (Psf1 homolog) |
| GINS2 | GINS complex subunit 2 (Psf2 homolog) |
| GPI | glucose-6-phosphate isomerase |
| GSTA1 | glutathione S-transferase alpha 1 |
| GSTM3 | glutathione S-transferase mu 3 (brain) |
| HIST1H4C | histone cluster 1, H4c |
| HK2 | hexokinase 2 |
| HPRT1 | hypoxanthine phosphoribosyltransferase 1 |
| HSPA8 | heat shock 70kDa protein 8 |
| ICMT | isoprenylcysteine carboxyl methyltransferase |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
| IFRD2 | interferon-related developmental regulator 2 |
| IGFBP5 | insulin-like growth factor binding protein 5 |
| IGHD | immunoglobulin heavy constant delta |
| IMPA2 | inositol(myo)-1(or 4)-monophosphatase 2 |
| KRT17 | keratin 17, type I |
| KRT6B | keratin 6B, type II |
| LGALS2 | lectin, galactoside-binding, soluble, 2 |
| LIMCH1 | LIM and calponin homology domains 1 |
| LRRC59 | leucine rich repeat containing 59 |
| MALL | mal, T-cell differentiation protein-like |
| MCAM | melanoma cell adhesion molecule |
| MCM10 | minichromosome maintenance complex component 10 |
| MCM3 | minichromosome maintenance complex component 3 |
| MCM7 | minichromosome maintenance complex component 7 |
| MRPL12 | mitochondrial ribosomal protein L12 |
| MTCH2 | mitochondrial carrier 2 |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 |
| MYBL2 | v-myb avian myeloblastosis viral oncogene homolog-like 2 |
| NME1 | NME/NM23 nucleoside diphosphate kinase 1 |
| NOP56 | NOP56 ribonucleoprotein |
| NUP93 | nucleoporin 93kDa |
| NVL | nuclear VCP-like |
| ODC1 | ornithine decarboxylase 1 |
| PAICS | phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase |
| PCNA | proliferating cell nuclear antigen |
| PGK1 | phosphoglycerate kinase 1 |
| PGM1 | phosphoglucomutase 1 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 |
| PNP | purine nucleoside phosphorylase |
| PPARG | peroxisome proliferator-activated receptor gamma |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
| PYCR1 | pyrroline-5-carboxylate reductase 1 |
| RANBP1 | RAN binding protein 1 |
| RFC3 | replication factor C (activator 1) 3, 38kDa |
| RFC4 | replication factor C (activator 1) 4, 37kDa |
| RFC5 | replication factor C (activator 1) 5, 36.5kDa |
| RRM2 | ribonucleotide reductase M2 |
| S100A7 | S100 calcium binding protein A7 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) |
| SDF2L1 | stromal cell-derived factor 2-like 1 |
| SFN | stratifin |
| SKP2 | S-phase kinase-associated protein 2, E3 ubiquitin protein ligase |
| SLPI | secretory leukocyte peptidase inhibitor |
| SNRNP25 | small nuclear ribonucleoprotein 25kDa (U11/U12) |
| SPRR3 | small proline-rich protein 3 |
| SRM | spermidine synthase |
| TFRC | transferrin receptor |
| TGFA | transforming growth factor, alpha |
| TIMELESS | timeless circadian clock |
| TMEM45A | transmembrane protein 45A |
| TOX3 | TOX high mobility group box family member 3 |
| TRD | T cell receptor delta locus |
| TRDV3 | T cell receptor delta variable 3 |
| TRIP13 | thyroid hormone receptor interactor 13 |
| TUBB2A | tubulin, beta 2A class IIa |
| TUBB6 | tubulin, beta 6 class V |
| TUBG1 | tubulin, gamma 1 |
| TYMS | thymidylate synthetase |
| UCHL3 | ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase) |
| VDAC3 | voltage-dependent anion channel 3 |
| WDR77 | WD repeat domain 77 |
| XIST | X inactive specific transcript (non-protein coding) |
| ZWINT | ZW10 interacting kinetochore protein |
