| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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279 genes differentially expressed following the BRD-A45498368_WYE-125132_HS578T_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ABCG1 | ATP-binding cassette, sub-family G (WHITE), member 1 |
| ADCK3 | aarF domain containing kinase 3 |
| AGTPBP1 | ATP/GTP binding protein 1 |
| AHNAK2 | AHNAK nucleoprotein 2 |
| AKAP9 | A kinase (PRKA) anchor protein 9 |
| AMDHD2 | amidohydrolase domain containing 2 |
| ANGPTL2 | angiopoietin-like 2 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) |
| ANKRD36B | ankyrin repeat domain 36B |
| ANXA4 | annexin A4 |
| ARMCX1 | armadillo repeat containing, X-linked 1 |
| ASPN | asporin |
| ATG12 | autophagy related 12 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding |
| C6ORF48 | chromosome 6 open reading frame 48 |
| CAMLG | calcium modulating ligand |
| CCNB1IP1 | cyclin B1 interacting protein 1, E3 ubiquitin protein ligase |
| CCNG2 | cyclin G2 |
| CDC25B | cell division cycle 25B |
| CDK19 | cyclin-dependent kinase 19 |
| CEP68 | centrosomal protein 68kDa |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) |
| CHRDL1 | chordin-like 1 |
| CIRBP | cold inducible RNA binding protein |
| CLEC2B | C-type lectin domain family 2, member B |
| COCH | cochlin |
| COL11A1 | collagen, type XI, alpha 1 |
| COL8A2 | collagen, type VIII, alpha 2 |
| COLEC11 | collectin sub-family member 11 |
| COX7A1 | cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) |
| CRYAB | crystallin, alpha B |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 |
| CTGF | connective tissue growth factor |
| CTSK | cathepsin K |
| DCLK1 | doublecortin-like kinase 1 |
| DICER1 | dicer 1, ribonuclease type III |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 |
| DLK1 | delta-like 1 homolog (Drosophila) |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 |
| DUSP3 | dual specificity phosphatase 3 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 |
| EMP1 | epithelial membrane protein 1 |
| F13A1 | coagulation factor XIII, A1 polypeptide |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 |
| FAM8A1 | family with sequence similarity 8, member A1 |
| FGF13 | fibroblast growth factor 13 |
| FNBP1 | formin binding protein 1 |
| FNTA | farnesyltransferase, CAAX box, alpha |
| FXR1 | fragile X mental retardation, autosomal homolog 1 |
| FXYD2 | FXYD domain containing ion transport regulator 2 |
| FZD7 | frizzled class receptor 7 |
| GAB2 | GRB2-associated binding protein 2 |
| GABBR1 | gamma-aminobutyric acid (GABA) B receptor, 1 |
| GCC2 | GRIP and coiled-coil domain containing 2 |
| GLG1 | golgi glycoprotein 1 |
| GPRASP1 | G protein-coupled receptor associated sorting protein 1 |
| GPRC5B | G protein-coupled receptor, class C, group 5, member B |
| GRB14 | growth factor receptor-bound protein 14 |
| GSE1 | Gse1 coiled-coil protein |
| GSN | gelsolin |
| GSPT2 | G1 to S phase transition 2 |
| HDAC6 | histone deacetylase 6 |
| HEPH | hephaestin |
| HIST3H2A | histone cluster 3, H2a |
| HMGA2 | high mobility group AT-hook 2 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 |
| HSPA2 | heat shock 70kDa protein 2 |
| HSPB7 | heat shock 27kDa protein family, member 7 (cardiovascular) |
| IDS | iduronate 2-sulfatase |
| IGBP1 | immunoglobulin (CD79A) binding protein 1 |
| IRS2 | insulin receptor substrate 2 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 |
| JADE2 | jade family PHD finger 2 |
| JUP | junction plakoglobin |
| KIAA1033 | KIAA1033 |
| KIF5C | kinesin family member 5C |
| KLHL21 | kelch-like family member 21 |
| KLHL24 | kelch-like family member 24 |
| LEPR | leptin receptor |
| LGALS3 | lectin, galactoside-binding, soluble, 3 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 |
| LINC00341 | long intergenic non-protein coding RNA 341 |
| LINC00342 | long intergenic non-protein coding RNA 342 |
| LXN | latexin |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MAGED1 | melanoma antigen family D1 |
| ME3 | malic enzyme 3, NADP(+)-dependent, mitochondrial |
| MFGE8 | milk fat globule-EGF factor 8 protein |
| MTMR11 | myotubularin related protein 11 |
| MYO6 | myosin VI |
| N4BP2L1 | NEDD4 binding protein 2-like 1 |
| NAP1L1 | nucleosome assembly protein 1-like 1 |
| NCOA3 | nuclear receptor coactivator 3 |
| NINL | ninein-like |
| NONO | non-POU domain containing, octamer-binding |
| NPC1 | Niemann-Pick disease, type C1 |
| NPDC1 | neural proliferation, differentiation and control, 1 |
| NPTX2 | neuronal pentraxin II |
| NT5E | 5'-nucleotidase, ecto (CD73) |
| OPTN | optineurin |
| PDE4B | phosphodiesterase 4B, cAMP-specific |
| PHYH | phytanoyl-CoA 2-hydroxylase |
| PILRB | paired immunoglobin-like type 2 receptor beta |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) |
| PLA2G4C | phospholipase A2, group IVC (cytosolic, calcium-independent) |
| PROM1 | prominin 1 |
| PRR15L | proline rich 15-like |
| PTGIS | prostaglandin I2 (prostacyclin) synthase |
| RAP2A | RAP2A, member of RAS oncogene family |
| RGS17 | regulator of G-protein signaling 17 |
| RRAGD | Ras-related GTP binding D |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 |
| SH3BP5 | SH3-domain binding protein 5 (BTK-associated) |
| SLC25A6 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 |
| SLC38A1 | solute carrier family 38, member 1 |
| SOD2 | superoxide dismutase 2, mitochondrial |
| SOX9 | SRY (sex determining region Y)-box 9 |
| ST18 | suppression of tumorigenicity 18, zinc finger |
| STX7 | syntaxin 7 |
| SULT1C2 | sulfotransferase family, cytosolic, 1C, member 2 |
| SYNM | synemin, intermediate filament protein |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) |
| TFPI2 | tissue factor pathway inhibitor 2 |
| THBS4 | thrombospondin 4 |
| TM4SF1 | transmembrane 4 L six family member 1 |
| TNPO1 | transportin 1 |
| TPR | translocated promoter region, nuclear basket protein |
| TRAK2 | trafficking protein, kinesin binding 2 |
| TRIB2 | tribbles pseudokinase 2 |
| TSPAN4 | tetraspanin 4 |
| TTC3 | tetratricopeptide repeat domain 3 |
| UBE2B | ubiquitin-conjugating enzyme E2B |
| VAT1 | vesicle amine transport 1 |
| VCAN | versican |
| VNN1 | vanin 1 |
| WDR13 | WD repeat domain 13 |
| WWP1 | WW domain containing E3 ubiquitin protein ligase 1 |
| ZDHHC11 | zinc finger, DHHC-type containing 11 |
| ZNF277 | zinc finger protein 277 |
| ZNF292 | zinc finger protein 292 |
| Symbol | Name |
|---|---|
| AARS | alanyl-tRNA synthetase |
| ACAT2 | acetyl-CoA acetyltransferase 2 |
| AKR1C3 | aldo-keto reductase family 1, member C3 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 |
| ALDH2 | aldehyde dehydrogenase 2 family (mitochondrial) |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 |
| ALG8 | ALG8, alpha-1,3-glucosyltransferase |
| APOC1 | apolipoprotein C-I |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) |
| ASPH | aspartate beta-hydroxylase |
| ATF6 | activating transcription factor 6 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 |
| C20ORF24 | chromosome 20 open reading frame 24 |
| CBS | cystathionine-beta-synthase |
| CCND3 | cyclin D3 |
| CCNE2 | cyclin E2 |
| CD320 | CD320 molecule |
| CDC25A | cell division cycle 25A |
| CDC45 | cell division cycle 45 |
| CDC6 | cell division cycle 6 |
| CDK2 | cyclin-dependent kinase 2 |
| CENPU | centromere protein U |
| CFH | complement factor H |
| CKAP4 | cytoskeleton-associated protein 4 |
| CKLF | chemokine-like factor |
| COL1A2 | collagen, type I, alpha 2 |
| CSRP2 | cysteine and glycine-rich protein 2 |
| CTPS1 | CTP synthase 1 |
| CTSC | cathepsin C |
| CTSZ | cathepsin Z |
| CXCL10 | chemokine (C-X-C motif) ligand 10 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| CYB5A | cytochrome b5 type A (microsomal) |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DHCR24 | 24-dehydrocholesterol reductase |
| DTL | denticleless E3 ubiquitin protein ligase homolog (Drosophila) |
| DUT | deoxyuridine triphosphatase |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 |
| EIF4EBP1 | eukaryotic translation initiation factor 4E binding protein 1 |
| EMP2 | epithelial membrane protein 2 |
| EMP3 | epithelial membrane protein 3 |
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 |
| EPHX1 | epoxide hydrolase 1, microsomal (xenobiotic) |
| ESR1 | estrogen receptor 1 |
| FADS1 | fatty acid desaturase 1 |
| FEN1 | flap structure-specific endonuclease 1 |
| FGFBP1 | fibroblast growth factor binding protein 1 |
| FKBP14 | FK506 binding protein 14, 22 kDa |
| FOLR1 | folate receptor 1 (adult) |
| GALE | UDP-galactose-4-epimerase |
| GBP1 | guanylate binding protein 1, interferon-inducible |
| GCLC | glutamate-cysteine ligase, catalytic subunit |
| GCLM | glutamate-cysteine ligase, modifier subunit |
| GINS1 | GINS complex subunit 1 (Psf1 homolog) |
| GINS2 | GINS complex subunit 2 (Psf2 homolog) |
| GINS3 | GINS complex subunit 3 (Psf3 homolog) |
| GLIPR1 | GLI pathogenesis-related 1 |
| GSTM3 | glutathione S-transferase mu 3 (brain) |
| GSTP1 | glutathione S-transferase pi 1 |
| HEG1 | heart development protein with EGF-like domains 1 |
| HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) |
| HSPB11 | heat shock protein family B (small), member 11 |
| ICMT | isoprenylcysteine carboxyl methyltransferase |
| IDI1 | isopentenyl-diphosphate delta isomerase 1 |
| IGKC | immunoglobulin kappa constant |
| LMNB1 | lamin B1 |
| LRRC17 | leucine rich repeat containing 17 |
| LRRC59 | leucine rich repeat containing 59 |
| LYZ | lysozyme |
| MANF | mesencephalic astrocyte-derived neurotrophic factor |
| MARS | methionyl-tRNA synthetase |
| MCAM | melanoma cell adhesion molecule |
| MCM10 | minichromosome maintenance complex component 10 |
| MCM2 | minichromosome maintenance complex component 2 |
| MCM3 | minichromosome maintenance complex component 3 |
| MCM5 | minichromosome maintenance complex component 5 |
| METTL7A | methyltransferase like 7A |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 |
| MSMO1 | methylsterol monooxygenase 1 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase |
| MYBL2 | v-myb avian myeloblastosis viral oncogene homolog-like 2 |
| MYCBP | MYC binding protein |
| NAT1 | N-acetyltransferase 1 (arylamine N-acetyltransferase) |
| NME1 | NME/NM23 nucleoside diphosphate kinase 1 |
| NME4 | NME/NM23 nucleoside diphosphate kinase 4 |
| PCNA | proliferating cell nuclear antigen |
| PDIA4 | protein disulfide isomerase family A, member 4 |
| PEX11A | peroxisomal biogenesis factor 11 alpha |
| PFN2 | profilin 2 |
| PGAM1 | phosphoglycerate mutase 1 (brain) |
| PGD | phosphogluconate dehydrogenase |
| PGK1 | phosphoglycerate kinase 1 |
| PHGDH | phosphoglycerate dehydrogenase |
| PIR | pirin (iron-binding nuclear protein) |
| PLAC8 | placenta-specific 8 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit |
| PON2 | paraoxonase 2 |
| PSAT1 | phosphoserine aminotransferase 1 |
| PYCR1 | pyrroline-5-carboxylate reductase 1 |
| RGS1 | regulator of G-protein signaling 1 |
| RPN2 | ribophorin II |
| RRM2 | ribonucleotide reductase M2 |
| S100A11 | S100 calcium binding protein A11 |
| SCARB1 | scavenger receptor class B, member 1 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) |
| SCGB2A1 | secretoglobin, family 2A, member 1 |
| SDF2L1 | stromal cell-derived factor 2-like 1 |
| SEL1L3 | sel-1 suppressor of lin-12-like 3 (C. elegans) |
| SFTPB | surfactant protein B |
| SKP2 | S-phase kinase-associated protein 2, E3 ubiquitin protein ligase |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 |
| SLC1A4 | solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SNRNP25 | small nuclear ribonucleoprotein 25kDa (U11/U12) |
| SORD | sorbitol dehydrogenase |
| SQLE | squalene epoxidase |
| SRGN | serglycin |
| STRA13 | stimulated by retinoic acid 13 |
| TARS | threonyl-tRNA synthetase |
| TIMELESS | timeless circadian clock |
| TK1 | thymidine kinase 1, soluble |
| TMEM14A | transmembrane protein 14A |
| TMEM176B | transmembrane protein 176B |
| TMEM97 | transmembrane protein 97 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
| TUBG1 | tubulin, gamma 1 |
| TYMS | thymidylate synthetase |
| WARS | tryptophanyl-tRNA synthetase |
| WNT5A | wingless-type MMTV integration site family, member 5A |
| YARS | tyrosyl-tRNA synthetase |
| ZWINT | ZW10 interacting kinetochore protein |
