Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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106 genes differentially expressed following the BRD-A45498368_WYE-125132_HT29_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 |
ADGRG6 | adhesion G protein-coupled receptor G6 |
BACE2 | beta-site APP-cleaving enzyme 2 |
CCNG2 | cyclin G2 |
CD200 | CD200 molecule |
CD24 | CD24 molecule |
CD44 | CD44 molecule (Indian blood group) |
CD9 | CD9 molecule |
CLIC5 | chloride intracellular channel 5 |
CRIP1 | cysteine-rich protein 1 (intestinal) |
CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 |
DKK3 | dickkopf WNT signaling pathway inhibitor 3 |
DOCK9 | dedicator of cytokinesis 9 |
DUSP6 | dual specificity phosphatase 6 |
EFNA1 | ephrin-A1 |
GAB2 | GRB2-associated binding protein 2 |
GAS6 | growth arrest-specific 6 |
GLTSCR2 | glioma tumor suppressor candidate region gene 2 |
GPX3 | glutathione peroxidase 3 |
GSN | gelsolin |
HLA-E | major histocompatibility complex, class I, E |
HOXD1 | homeobox D1 |
IFI6 | interferon, alpha-inducible protein 6 |
IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 |
IFITM1 | interferon induced transmembrane protein 1 |
JUP | junction plakoglobin |
LGALS3 | lectin, galactoside-binding, soluble, 3 |
LXN | latexin |
MACF1 | microtubule-actin crosslinking factor 1 |
MBNL2 | muscleblind-like splicing regulator 2 |
MSLN | mesothelin |
MX1 | MX dynamin-like GTPase 1 |
MYRF | myelin regulatory factor |
N4BP2L1 | NEDD4 binding protein 2-like 1 |
NPDC1 | neural proliferation, differentiation and control, 1 |
OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa |
PDZD2 | PDZ domain containing 2 |
PLK2 | polo-like kinase 2 |
PMP22 | peripheral myelin protein 22 |
POLD4 | polymerase (DNA-directed), delta 4, accessory subunit |
PTPRE | protein tyrosine phosphatase, receptor type, E |
RAB4A | RAB4A, member RAS oncogene family |
RABAC1 | Rab acceptor 1 (prenylated) |
RAP1GAP | RAP1 GTPase activating protein |
RAPGEF5 | Rap guanine nucleotide exchange factor (GEF) 5 |
SCNN1A | sodium channel, non voltage gated 1 alpha subunit |
SH3YL1 | SH3 and SYLF domain containing 1 |
SOX9 | SRY (sex determining region Y)-box 9 |
SQSTM1 | sequestosome 1 |
SST | somatostatin |
TIMP2 | TIMP metallopeptidase inhibitor 2 |
TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 |
TRAPPC6A | trafficking protein particle complex 6A |
WT1 | Wilms tumor 1 |
ZMIZ1 | zinc finger, MIZ-type containing 1 |
Symbol | Name |
---|---|
ACTG2 | actin, gamma 2, smooth muscle, enteric |
AMMECR1 | Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1 |
AURKA | aurora kinase A |
BIRC5 | baculoviral IAP repeat containing 5 |
CALB1 | calbindin 1, 28kDa |
CAV1 | caveolin 1, caveolae protein, 22kDa |
CCL2 | chemokine (C-C motif) ligand 2 |
CDC25A | cell division cycle 25A |
CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
CSRP2 | cysteine and glycine-rich protein 2 |
CSTA | cystatin A (stefin A) |
CXCL13 | chemokine (C-X-C motif) ligand 13 |
CXCL9 | chemokine (C-X-C motif) ligand 9 |
DDIT4 | DNA-damage-inducible transcript 4 |
DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 |
EXOSC4 | exosome component 4 |
FABP7 | fatty acid binding protein 7, brain |
GCLM | glutamate-cysteine ligase, modifier subunit |
GRB14 | growth factor receptor-bound protein 14 |
GSTA1 | glutathione S-transferase alpha 1 |
HIGD1A | HIG1 hypoxia inducible domain family, member 1A |
HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
HOXA10 | homeobox A10 |
IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 |
LBR | lamin B receptor |
LTF | lactotransferrin |
LYN | LYN proto-oncogene, Src family tyrosine kinase |
MAGEA3 | melanoma antigen family A3 |
MAGEA6 | melanoma antigen family A6 |
MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 |
MMP9 | matrix metallopeptidase 9 |
MSMO1 | methylsterol monooxygenase 1 |
MYCBP | MYC binding protein |
MYLK | myosin light chain kinase |
NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 |
OLFM4 | olfactomedin 4 |
PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 |
PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta |
PSPH | phosphoserine phosphatase |
RAD23B | RAD23 homolog B (S. cerevisiae) |
RRM2 | ribonucleotide reductase M2 |
SLC2A5 | solute carrier family 2 (facilitated glucose/fructose transporter), member 5 |
SORD | sorbitol dehydrogenase |
SQLE | squalene epoxidase |
TFAP2B | transcription factor AP-2 beta (activating enhancer binding protein 2 beta) |
TFF3 | trefoil factor 3 (intestinal) |
TFPI2 | tissue factor pathway inhibitor 2 |
TRAPPC3 | trafficking protein particle complex 3 |
UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) |