Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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118 genes differentially expressed following the BRD-A45498368_WYE-125132_MCF7_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
ACKR3 | atypical chemokine receptor 3 |
ARHGAP32 | Rho GTPase activating protein 32 |
ATP9A | ATPase, class II, type 9A |
C2CD5 | C2 calcium-dependent domain containing 5 |
C6ORF48 | chromosome 6 open reading frame 48 |
CAST | calpastatin |
CCNG2 | cyclin G2 |
CD24 | CD24 molecule |
CDK5RAP3 | CDK5 regulatory subunit associated protein 3 |
DIAPH2 | diaphanous-related formin 2 |
DKK3 | dickkopf WNT signaling pathway inhibitor 3 |
EIF3F | eukaryotic translation initiation factor 3, subunit F |
EIF3L | eukaryotic translation initiation factor 3, subunit L |
EIF4B | eukaryotic translation initiation factor 4B |
ERBB2 | erb-b2 receptor tyrosine kinase 2 |
EVL | Enah/Vasp-like |
FBN2 | fibrillin 2 |
FCGBP | Fc fragment of IgG binding protein |
FEZ1 | fasciculation and elongation protein zeta 1 (zygin I) |
FXR1 | fragile X mental retardation, autosomal homolog 1 |
GLTSCR2 | glioma tumor suppressor candidate region gene 2 |
GOLGA8A | golgin A8 family, member A |
GPR137B | G protein-coupled receptor 137B |
GRN | granulin |
HBP1 | HMG-box transcription factor 1 |
HIST3H2A | histone cluster 3, H2a |
HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 |
IGBP1 | immunoglobulin (CD79A) binding protein 1 |
IGF1R | insulin-like growth factor 1 receptor |
IGFBP7 | insulin-like growth factor binding protein 7 |
KLHL24 | kelch-like family member 24 |
LETMD1 | LETM1 domain containing 1 |
LTA4H | leukotriene A4 hydrolase |
MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B |
MAP2K5 | mitogen-activated protein kinase kinase 5 |
MARCKSL1 | MARCKS-like 1 |
MTA1 | metastasis associated 1 |
MXI1 | MAX interactor 1, dimerization protein |
MYC | v-myc avian myelocytomatosis viral oncogene homolog |
NSG1 | neuron specific gene family member 1 |
PAN2 | PAN2 poly(A) specific ribonuclease subunit |
PCBP2 | poly(rC) binding protein 2 |
PDLIM1 | PDZ and LIM domain 1 |
PGLS | 6-phosphogluconolactonase |
PNRC1 | proline-rich nuclear receptor coactivator 1 |
POLR1D | polymerase (RNA) I polypeptide D, 16kDa |
PRKCQ | protein kinase C, theta |
RIN2 | Ras and Rab interactor 2 |
RPL15 | ribosomal protein L15 |
RPS11 | ribosomal protein S11 |
SAT1 | spermidine/spermine N1-acetyltransferase 1 |
SH3BGRL | SH3 domain binding glutamate-rich protein like |
SMAD3 | SMAD family member 3 |
SPATA20 | spermatogenesis associated 20 |
ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 |
TPP1 | tripeptidyl peptidase I |
WASL | Wiskott-Aldrich syndrome-like |
ZHX2 | zinc fingers and homeoboxes 2 |
ZNF91 | zinc finger protein 91 |
Symbol | Name |
---|---|
ACLY | ATP citrate lyase |
ACOT7 | acyl-CoA thioesterase 7 |
AQP3 | aquaporin 3 (Gill blood group) |
ASNS | asparagine synthetase (glutamine-hydrolyzing) |
ATAD2 | ATPase family, AAA domain containing 2 |
BST2 | bone marrow stromal cell antigen 2 |
C3 | complement component 3 |
CALCA | calcitonin-related polypeptide alpha |
CDC25A | cell division cycle 25A |
CDC6 | cell division cycle 6 |
CDKN3 | cyclin-dependent kinase inhibitor 3 |
CKS1B | CDC28 protein kinase regulatory subunit 1B |
COL3A1 | collagen, type III, alpha 1 |
CPM | carboxypeptidase M |
CXCL2 | chemokine (C-X-C motif) ligand 2 |
CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 |
DHCR7 | 7-dehydrocholesterol reductase |
DNAJC9 | DnaJ (Hsp40) homolog, subfamily C, member 9 |
DTL | denticleless E3 ubiquitin protein ligase homolog (Drosophila) |
EBP | emopamil binding protein (sterol isomerase) |
ENO1 | enolase 1, (alpha) |
EREG | epiregulin |
GINS2 | GINS complex subunit 2 (Psf2 homolog) |
GLIPR1 | GLI pathogenesis-related 1 |
HSPA8 | heat shock 70kDa protein 8 |
ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
IER3 | immediate early response 3 |
IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
IMPA2 | inositol(myo)-1(or 4)-monophosphatase 2 |
ISG15 | ISG15 ubiquitin-like modifier |
LRRC59 | leucine rich repeat containing 59 |
LTF | lactotransferrin |
MALL | mal, T-cell differentiation protein-like |
MARS | methionyl-tRNA synthetase |
MCM10 | minichromosome maintenance complex component 10 |
MYBL2 | v-myb avian myeloblastosis viral oncogene homolog-like 2 |
NME1 | NME/NM23 nucleoside diphosphate kinase 1 |
NPR3 | natriuretic peptide receptor 3 |
ODC1 | ornithine decarboxylase 1 |
PGC | progastricsin (pepsinogen C) |
PNP | purine nucleoside phosphorylase |
POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit |
PSMC3 | proteasome (prosome, macropain) 26S subunit, ATPase, 3 |
RFC3 | replication factor C (activator 1) 3, 38kDa |
RRM2 | ribonucleotide reductase M2 |
SDC2 | syndecan 2 |
SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 |
SQLE | squalene epoxidase |
STIP1 | stress-induced phosphoprotein 1 |
TAGLN2 | transgelin 2 |
TFRC | transferrin receptor |
TK1 | thymidine kinase 1, soluble |
TSPYL5 | TSPY-like 5 |
TUBA4A | tubulin, alpha 4a |
TUBB6 | tubulin, beta 6 class V |
TUBG1 | tubulin, gamma 1 |
UBE2S | ubiquitin-conjugating enzyme E2S |
USP7 | ubiquitin specific peptidase 7 (herpes virus-associated) |