| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
| Downloads & Tools |
159 genes differentially expressed following the BRD-A47829399_artesunate_PC3_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| AARS | alanyl-tRNA synthetase |
| ADAMDEC1 | ADAM-like, decysin 1 |
| ALAS1 | 5'-aminolevulinate synthase 1 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 |
| ARHGEF2 | Rho/Rac guanine nucleotide exchange factor (GEF) 2 |
| ARMCX2 | armadillo repeat containing, X-linked 2 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) |
| ATF3 | activating transcription factor 3 |
| CBS | cystathionine-beta-synthase |
| CCPG1 | cell cycle progression 1 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| CEMIP | cell migration inducing protein, hyaluronan binding |
| CHGB | chromogranin B |
| CTH | cystathionine gamma-lyase |
| CXCL2 | chemokine (C-X-C motif) ligand 2 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| EGFR | epidermal growth factor receptor |
| EIF4EBP1 | eukaryotic translation initiation factor 4E binding protein 1 |
| EPAS1 | endothelial PAS domain protein 1 |
| FBN2 | fibrillin 2 |
| FKBP11 | FK506 binding protein 11, 19 kDa |
| GADD45A | growth arrest and DNA-damage-inducible, alpha |
| GAGE3 | G antigen 3 |
| GARS | glycyl-tRNA synthetase |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 |
| GPM6B | glycoprotein M6B |
| GRB10 | growth factor receptor-bound protein 10 |
| GTPBP2 | GTP binding protein 2 |
| HMOX1 | heme oxygenase 1 |
| IER3 | immediate early response 3 |
| IFI27 | interferon, alpha-inducible protein 27 |
| IL1A | interleukin 1, alpha |
| IL1B | interleukin 1, beta |
| LGALS4 | lectin, galactoside-binding, soluble, 4 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta |
| MARS | methionyl-tRNA synthetase |
| MMP1 | matrix metallopeptidase 1 |
| MMP3 | matrix metallopeptidase 3 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 |
| PCK2 | phosphoenolpyruvate carboxykinase 2 (mitochondrial) |
| PDGFA | platelet-derived growth factor alpha polypeptide |
| PHGDH | phosphoglycerate dehydrogenase |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 |
| PSAT1 | phosphoserine aminotransferase 1 |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 |
| PYCR1 | pyrroline-5-carboxylate reductase 1 |
| REG1A | regenerating islet-derived 1 alpha |
| RGS5 | regulator of G-protein signaling 5 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 |
| RSL24D1 | ribosomal L24 domain containing 1 |
| SCG5 | secretogranin V |
| SERPINI1 | serpin peptidase inhibitor, clade I (neuroserpin), member 1 |
| SLC1A4 | solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 |
| SLC38A1 | solute carrier family 38, member 1 |
| SLC3A2 | solute carrier family 3 (amino acid transporter heavy chain), member 2 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 |
| STC2 | stanniocalcin 2 |
| TCEA1 | transcription elongation factor A (SII), 1 |
| THBD | thrombomodulin |
| TOX3 | TOX high mobility group box family member 3 |
| TRD | T cell receptor delta locus |
| TRDV3 | T cell receptor delta variable 3 |
| TRIB3 | tribbles pseudokinase 3 |
| TUFT1 | tuftelin 1 |
| VEGFA | vascular endothelial growth factor A |
| WARS | tryptophanyl-tRNA synthetase |
| WIPI1 | WD repeat domain, phosphoinositide interacting 1 |
| XBP1 | X-box binding protein 1 |
| XPOT | exportin, tRNA |
| ZSCAN18 | zinc finger and SCAN domain containing 18 |
| Symbol | Name |
|---|---|
| ACTN1 | actinin, alpha 1 |
| AIM1 | absent in melanoma 1 |
| ANKRD10 | ankyrin repeat domain 10 |
| ATAD2 | ATPase family, AAA domain containing 2 |
| B3GNT1 | |
| BAG3 | BCL2-associated athanogene 3 |
| BIRC5 | baculoviral IAP repeat containing 5 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 |
| CBR3 | carbonyl reductase 3 |
| CCND3 | cyclin D3 |
| CCNE2 | cyclin E2 |
| CDC25A | cell division cycle 25A |
| CDCA4 | cell division cycle associated 4 |
| CILP | cartilage intermediate layer protein, nucleotide pyrophosphohydrolase |
| CRYZ | crystallin, zeta (quinone reductase) |
| DBI | diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) |
| DHFR | dihydrofolate reductase |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 |
| DNAJC9 | DnaJ (Hsp40) homolog, subfamily C, member 9 |
| DTL | denticleless E3 ubiquitin protein ligase homolog (Drosophila) |
| EBP | emopamil binding protein (sterol isomerase) |
| EGR3 | early growth response 3 |
| ENO1 | enolase 1, (alpha) |
| F12 | coagulation factor XII (Hageman factor) |
| FBLN1 | fibulin 1 |
| FEN1 | flap structure-specific endonuclease 1 |
| GINS1 | GINS complex subunit 1 (Psf1 homolog) |
| GINS2 | GINS complex subunit 2 (Psf2 homolog) |
| GMNN | geminin, DNA replication inhibitor |
| GPI | glucose-6-phosphate isomerase |
| GPX3 | glutathione peroxidase 3 |
| HOXA10 | homeobox A10 |
| HSPA8 | heat shock 70kDa protein 8 |
| HSPB8 | heat shock 22kDa protein 8 |
| ICMT | isoprenylcysteine carboxyl methyltransferase |
| IGF1 | insulin-like growth factor 1 (somatomedin C) |
| IL27RA | interleukin 27 receptor, alpha |
| KCTD12 | potassium channel tetramerization domain containing 12 |
| KIAA0101 | KIAA0101 |
| KIF20A | kinesin family member 20A |
| LMNB1 | lamin B1 |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B |
| MCM10 | minichromosome maintenance complex component 10 |
| MCM2 | minichromosome maintenance complex component 2 |
| MCM3 | minichromosome maintenance complex component 3 |
| MCM4 | minichromosome maintenance complex component 4 |
| MCM6 | minichromosome maintenance complex component 6 |
| MCM7 | minichromosome maintenance complex component 7 |
| MRPS12 | mitochondrial ribosomal protein S12 |
| MTHFD1 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase |
| MYB | v-myb avian myeloblastosis viral oncogene homolog |
| MYBL2 | v-myb avian myeloblastosis viral oncogene homolog-like 2 |
| NCAPD3 | non-SMC condensin II complex, subunit D3 |
| NR2F2 | nuclear receptor subfamily 2, group F, member 2 |
| PCNA | proliferating cell nuclear antigen |
| PFKP | phosphofructokinase, platelet |
| PTDSS1 | phosphatidylserine synthase 1 |
| RFC2 | replication factor C (activator 1) 2, 40kDa |
| RFC5 | replication factor C (activator 1) 5, 36.5kDa |
| RRM1 | ribonucleotide reductase M1 |
| RRM2 | ribonucleotide reductase M2 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 |
| SORD | sorbitol dehydrogenase |
| SOX4 | SRY (sex determining region Y)-box 4 |
| SPDEF | SAM pointed domain containing ETS transcription factor |
| SPR | sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) |
| STIP1 | stress-induced phosphoprotein 1 |
| STMN1 | stathmin 1 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) |
| TFDP1 | transcription factor Dp-1 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) |
| TGM2 | transglutaminase 2 |
| TK1 | thymidine kinase 1, soluble |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 |
| TUBB | tubulin, beta class I |
| TYMS | thymidylate synthetase |
| VCAN | versican |
| WWTR1 | WW domain containing transcription regulator 1 |
| ZBTB18 | zinc finger and BTB domain containing 18 |
| ZWINT | ZW10 interacting kinetochore protein |
