BRD-A48570745_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

18 genes differentially expressed following the BRD-A48570745_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ANXA3 annexin A3
AREG amphiregulin
CD24 CD24 molecule
EREG epiregulin
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
ISG20 interferon stimulated exonuclease gene 20kDa
LDOC1 leucine zipper, down-regulated in cancer 1
TMEM176B transmembrane protein 176B
TSC22D3 TSC22 domain family, member 3
VEGFA vascular endothelial growth factor A

decreased expression

Symbol Name
FERMT2 fermitin family member 2
MEIS2 Meis homeobox 2
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
SORBS1 sorbin and SH3 domain containing 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
TCF4 transcription factor 4
ZW10 zw10 kinetochore protein
Funding