BRD-A50675702_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

99 genes differentially expressed following the BRD-A50675702_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AARS alanyl-tRNA synthetase
ADGRF5 adhesion G protein-coupled receptor F5
ADGRG2 adhesion G protein-coupled receptor G2
ADIRF adipogenesis regulatory factor
AGTR1 angiotensin II receptor, type 1
AHR aryl hydrocarbon receptor
APOD apolipoprotein D
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ASNS asparagine synthetase (glutamine-hydrolyzing)
C6ORF62 chromosome 6 open reading frame 62
CBS cystathionine-beta-synthase
CCNB1IP1 cyclin B1 interacting protein 1, E3 ubiquitin protein ligase
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CPE carboxypeptidase E
CXCL14 chemokine (C-X-C motif) ligand 14
CXCR4 chemokine (C-X-C motif) receptor 4
DACH1 dachshund family transcription factor 1
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DLK1 delta-like 1 homolog (Drosophila)
DPYSL2 dihydropyrimidinase-like 2
ELN elastin
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
ESRP1 epithelial splicing regulatory protein 1
F13A1 coagulation factor XIII, A1 polypeptide
FGFR1 fibroblast growth factor receptor 1
FST follistatin
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3
GARS glycyl-tRNA synthetase
H1F0 H1 histone family, member 0
HMOX1 heme oxygenase 1
IGFBP7 insulin-like growth factor binding protein 7
JAG1 jagged 1
MAP7 microtubule-associated protein 7
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
NUPR1 nuclear protein, transcriptional regulator, 1
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PEG10 paternally expressed 10
PERP PERP, TP53 apoptosis effector
PHGDH phosphoglycerate dehydrogenase
PKP2 plakophilin 2
PLXNA2 plexin A2
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PPP1R16B protein phosphatase 1, regulatory subunit 16B
PSAT1 phosphoserine aminotransferase 1
PTGDS prostaglandin D2 synthase 21kDa (brain)
PTPRO protein tyrosine phosphatase, receptor type, O
PYCR1 pyrroline-5-carboxylate reductase 1
RGCC regulator of cell cycle
RPS4Y1 ribosomal protein S4, Y-linked 1
SARS seryl-tRNA synthetase
SGCE sarcoglycan, epsilon
SH3YL1 SH3 and SYLF domain containing 1
SRGN serglycin
STC2 stanniocalcin 2
SYNJ2 synaptojanin 2
TMEM30B transmembrane protein 30B
TPPP3 tubulin polymerization-promoting protein family member 3
TRIB3 tribbles pseudokinase 3
XBP1 X-box binding protein 1
XPOT exportin, tRNA

decreased expression

Symbol Name
ACADVL acyl-CoA dehydrogenase, very long chain
ADA adenosine deaminase
AKAP7 A kinase (PRKA) anchor protein 7
AMIGO2 adhesion molecule with Ig-like domain 2
CENPE centromere protein E, 312kDa
COL7A1 collagen, type VII, alpha 1
CPS1 carbamoyl-phosphate synthase 1, mitochondrial
CXCL5 chemokine (C-X-C motif) ligand 5
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14
GALNT2 polypeptide N-acetylgalactosaminyltransferase 2
GALNT7 polypeptide N-acetylgalactosaminyltransferase 7
GOLGA8A golgin A8 family, member A
HMG20B high mobility group 20B
IRS2 insulin receptor substrate 2
KYNU kynureninase
MAGEA1 melanoma antigen family A1
MAGEA12 melanoma antigen family A12
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
NTS neurotensin
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PRAME preferentially expressed antigen in melanoma
PSCA prostate stem cell antigen
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RHOB ras homolog family member B
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
S100A8 S100 calcium binding protein A8
SEPT6 septin 6
SORBS1 sorbin and SH3 domain containing 1
TBC1D9B TBC1 domain family, member 9B (with GRAM domain)
TFPI2 tissue factor pathway inhibitor 2
TGM2 transglutaminase 2
TKTL1 transketolase-like 1
TMEM164 transmembrane protein 164
WNT5A wingless-type MMTV integration site family, member 5A
XIST X inactive specific transcript (non-protein coding)