BRD-A55416093_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

76 genes differentially expressed following the BRD-A55416093_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADI1 acireductone dioxygenase 1
ADM adrenomedullin
ALCAM activated leukocyte cell adhesion molecule
ARID4B AT rich interactive domain 4B (RBP1-like)
BASP1 brain abundant, membrane attached signal protein 1
BTG1 B-cell translocation gene 1, anti-proliferative
CD24 CD24 molecule
CD36 CD36 molecule (thrombospondin receptor)
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CLU clusterin
CPB1 carboxypeptidase B1 (tissue)
CPE carboxypeptidase E
CYTIP cytohesin 1 interacting protein
DDIT4 DNA-damage-inducible transcript 4
DHRS2 dehydrogenase/reductase (SDR family) member 2
DUSP4 dual specificity phosphatase 4
DYNLT3 dynein, light chain, Tctex-type 3
GOLGA8A golgin A8 family, member A
GREB1 growth regulation by estrogen in breast cancer 1
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HNMT histamine N-methyltransferase
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
IGFBP5 insulin-like growth factor binding protein 5
KRT7 keratin 7, type II
LAMP5 lysosomal-associated membrane protein family, member 5
LYZ lysozyme
MAP7 microtubule-associated protein 7
MAPK13 mitogen-activated protein kinase 13
MTA1 metastasis associated 1
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
PLXNC1 plexin C1
S100A8 S100 calcium binding protein A8
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1
SDC2 syndecan 2
SLC16A6 solute carrier family 16, member 6
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC27A3 solute carrier family 27 (fatty acid transporter), member 3
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
TBX3 T-box 3
TFF1 trefoil factor 1
THBS1 thrombospondin 1
TMEM2 transmembrane protein 2
TMEM30B transmembrane protein 30B
VCAN versican

decreased expression

Symbol Name
ADRB2 adrenoceptor beta 2, surface
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
CD59 CD59 molecule, complement regulatory protein
DKK1 dickkopf WNT signaling pathway inhibitor 1
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2)
EML3 echinoderm microtubule associated protein like 3
EPHA2 EPH receptor A2
GPM6B glycoprotein M6B
GSAP gamma-secretase activating protein
H3F3B H3 histone, family 3B (H3.3B)
HMGA2 high mobility group AT-hook 2
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
ITGA6 integrin, alpha 6
KANK2 KN motif and ankyrin repeat domains 2
LAMC2 laminin, gamma 2
MBP myelin basic protein
MOK MOK protein kinase
NKX3-1 NK3 homeobox 1
PDGFA platelet-derived growth factor alpha polypeptide
PRKCA protein kinase C, alpha
PTPN12 protein tyrosine phosphatase, non-receptor type 12
S100A2 S100 calcium binding protein A2
SMAGP small cell adhesion glycoprotein
SOX9 SRY (sex determining region Y)-box 9
SPRY2 sprouty homolog 2 (Drosophila)
TGFB1I1 transforming growth factor beta 1 induced transcript 1
TM4SF1 transmembrane 4 L six family member 1
UGCG UDP-glucose ceramide glucosyltransferase
Funding