Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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217 genes differentially expressed following the BRD-A55484088_BNTX maleate_MCF7_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
AAK1 | AP2 associated kinase 1 |
ABHD4 | abhydrolase domain containing 4 |
ADM | adrenomedullin |
AKAP17A | A kinase (PRKA) anchor protein 17A |
AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) |
AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) |
AKR1C1 | aldo-keto reductase family 1, member C1 |
AKR1C2 | aldo-keto reductase family 1, member C2 |
ANKRD12 | ankyrin repeat domain 12 |
ATF3 | activating transcription factor 3 |
ATG101 | autophagy related 101 |
BAG3 | BCL2-associated athanogene 3 |
BMP2 | bone morphogenetic protein 2 |
BRD2 | bromodomain containing 2 |
BRD4 | bromodomain containing 4 |
CADM1 | cell adhesion molecule 1 |
CAPN2 | calpain 2, (m/II) large subunit |
CCL5 | chemokine (C-C motif) ligand 5 |
CCNL1 | cyclin L1 |
CHORDC1 | cysteine and histidine-rich domain (CHORD) containing 1 |
COL1A1 | collagen, type I, alpha 1 |
COL1A2 | collagen, type I, alpha 2 |
COL3A1 | collagen, type III, alpha 1 |
COL6A2 | collagen, type VI, alpha 2 |
CYLD | cylindromatosis (turban tumor syndrome) |
DDIT3 | DNA-damage-inducible transcript 3 |
DLX2 | distal-less homeobox 2 |
DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 |
DNAJB4 | DnaJ (Hsp40) homolog, subfamily B, member 4 |
DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 |
DUSP1 | dual specificity phosphatase 1 |
DUSP5 | dual specificity phosphatase 5 |
EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 |
ENC1 | ectodermal-neural cortex 1 (with BTB domain) |
EPHX1 | epoxide hydrolase 1, microsomal (xenobiotic) |
EZR | ezrin |
F3 | coagulation factor III (thromboplastin, tissue factor) |
FN1 | fibronectin 1 |
FOSL2 | FOS-like antigen 2 |
FTL | ferritin, light polypeptide |
GABARAPL1 | GABA(A) receptor-associated protein like 1 |
GABPB1 | GA binding protein transcription factor, beta subunit 1 |
GADD45A | growth arrest and DNA-damage-inducible, alpha |
GADD45B | growth arrest and DNA-damage-inducible, beta |
GATA6 | GATA binding protein 6 |
GEM | GTP binding protein overexpressed in skeletal muscle |
HBEGF | heparin-binding EGF-like growth factor |
HCAR3 | hydroxycarboxylic acid receptor 3 |
HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 |
HMOX1 | heme oxygenase 1 |
HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
HSPD1 | heat shock 60kDa protein 1 (chaperonin) |
HSPH1 | heat shock 105kDa/110kDa protein 1 |
ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
IGHD | immunoglobulin heavy constant delta |
IL10RA | interleukin 10 receptor, alpha |
ITCH | itchy E3 ubiquitin protein ligase |
JAG1 | jagged 1 |
JMJD6 | jumonji domain containing 6 |
JUN | jun proto-oncogene |
KCMF1 | potassium channel modulatory factor 1 |
KCTD5 | potassium channel tetramerization domain containing 5 |
KDM3A | lysine (K)-specific demethylase 3A |
KLF4 | Kruppel-like factor 4 (gut) |
KRT6A | keratin 6A, type II |
LBH | limb bud and heart development |
LCN2 | lipocalin 2 |
LMO4 | LIM domain only 4 |
MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
MAP1LC3B | microtubule-associated protein 1 light chain 3 beta |
MICALL1 | MICAL-like 1 |
MIR22HG | MIR22 host gene |
MYO10 | myosin X |
NDRG1 | N-myc downstream regulated 1 |
NFIL3 | nuclear factor, interleukin 3 regulated |
OSER1 | oxidative stress responsive serine-rich 1 |
P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II |
PDGFA | platelet-derived growth factor alpha polypeptide |
PDXK | pyridoxal (pyridoxine, vitamin B6) kinase |
PGC | progastricsin (pepsinogen C) |
PKP1 | plakophilin 1 |
PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 |
PPP1R15A | protein phosphatase 1, regulatory subunit 15A |
RANBP2 | RAN binding protein 2 |
RIOK3 | RIO kinase 3 |
RIT1 | Ras-like without CAAX 1 |
RLF | rearranged L-myc fusion |
RND3 | Rho family GTPase 3 |
RNF19B | ring finger protein 19B |
RYBP | RING1 and YY1 binding protein |
SAT1 | spermidine/spermine N1-acetyltransferase 1 |
SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) |
SFTPA2 | surfactant protein A2 |
SFTPB | surfactant protein B |
SFTPC | surfactant protein C |
SIK1 | salt-inducible kinase 1 |
SMAD7 | SMAD family member 7 |
SOWAHC | sosondowah ankyrin repeat domain family member C |
STX1A | syntaxin 1A (brain) |
STX3 | syntaxin 3 |
TRIB1 | tribbles pseudokinase 1 |
TUBA4A | tubulin, alpha 4a |
TUFT1 | tuftelin 1 |
TXNRD1 | thioredoxin reductase 1 |
UBR4 | ubiquitin protein ligase E3 component n-recognin 4 |
UPP1 | uridine phosphorylase 1 |
VEGFA | vascular endothelial growth factor A |
YAP1 | Yes-associated protein 1 |
ZBTB43 | zinc finger and BTB domain containing 43 |
ZFP36 | ZFP36 ring finger protein |
Symbol | Name |
---|---|
ABLIM1 | actin binding LIM protein 1 |
ADD3 | adducin 3 (gamma) |
APOD | apolipoprotein D |
ARL6IP5 | ADP-ribosylation factor-like 6 interacting protein 5 |
ARMT1 | acidic residue methyltransferase 1 |
ATP1A2 | ATPase, Na+/K+ transporting, alpha 2 polypeptide |
AURKA | aurora kinase A |
AZGP1 | alpha-2-glycoprotein 1, zinc-binding |
B3GNT1 | |
BDH1 | 3-hydroxybutyrate dehydrogenase, type 1 |
BHLHE41 | basic helix-loop-helix family, member e41 |
BUB1 | BUB1 mitotic checkpoint serine/threonine kinase |
CA12 | carbonic anhydrase XII |
CCNA2 | cyclin A2 |
CD36 | CD36 molecule (thrombospondin receptor) |
CDC20 | cell division cycle 20 |
CDK1 | cyclin-dependent kinase 1 |
CDK2 | cyclin-dependent kinase 2 |
CDKN3 | cyclin-dependent kinase inhibitor 3 |
CENPA | centromere protein A |
CHRDL1 | chordin-like 1 |
CILP | cartilage intermediate layer protein, nucleotide pyrophosphohydrolase |
CRABP2 | cellular retinoic acid binding protein 2 |
CXCL12 | chemokine (C-X-C motif) ligand 12 |
DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 |
DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 |
DMD | dystrophin |
DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 |
DUT | deoxyuridine triphosphatase |
EBP | emopamil binding protein (sterol isomerase) |
EIF5A | eukaryotic translation initiation factor 5A |
ESR1 | estrogen receptor 1 |
FKBP3 | FK506 binding protein 3, 25kDa |
GALNT6 | polypeptide N-acetylgalactosaminyltransferase 6 |
GAS1 | growth arrest-specific 1 |
GINS2 | GINS complex subunit 2 (Psf2 homolog) |
GTF3A | general transcription factor IIIA |
HADH | hydroxyacyl-CoA dehydrogenase |
HMGB2 | high mobility group box 2 |
HMMR | hyaluronan-mediated motility receptor (RHAMM) |
HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) |
IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
IFITM1 | interferon induced transmembrane protein 1 |
IFITM2 | interferon induced transmembrane protein 2 |
IGF1 | insulin-like growth factor 1 (somatomedin C) |
IGFBP4 | insulin-like growth factor binding protein 4 |
IMPDH2 | IMP (inosine 5'-monophosphate) dehydrogenase 2 |
ISOC1 | isochorismatase domain containing 1 |
KIAA0101 | KIAA0101 |
KIF20A | kinesin family member 20A |
KPNA2 | karyopherin alpha 2 (RAG cohort 1, importin alpha 1) |
LEPR | leptin receptor |
LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein |
LIG1 | ligase I, DNA, ATP-dependent |
LIPA | lipase A, lysosomal acid, cholesterol esterase |
LXN | latexin |
MAD2L1 | MAD2 mitotic arrest deficient-like 1 (yeast) |
MAGED2 | melanoma antigen family D2 |
MAPT | microtubule-associated protein tau |
MARCKS | myristoylated alanine-rich protein kinase C substrate |
MFAP5 | microfibrillar associated protein 5 |
MREG | melanoregulin |
MUC1 | mucin 1, cell surface associated |
MYB | v-myb avian myeloblastosis viral oncogene homolog |
NBN | nibrin |
NHP2 | NHP2 ribonucleoprotein |
OGN | osteoglycin |
OLFM1 | olfactomedin 1 |
PAICS | phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase |
PBK | PDZ binding kinase |
PCNA | proliferating cell nuclear antigen |
PDGFRL | platelet-derived growth factor receptor-like |
PIP | prolactin-induced protein |
PLK1 | polo-like kinase 1 |
POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit |
POLG2 | polymerase (DNA directed), gamma 2, accessory subunit |
PSENEN | presenilin enhancer gamma secretase subunit |
PTTG1 | pituitary tumor-transforming 1 |
RASSF2 | Ras association (RalGDS/AF-6) domain family member 2 |
RBM3 | RNA binding motif (RNP1, RRM) protein 3 |
RET | ret proto-oncogene |
RFC3 | replication factor C (activator 1) 3, 38kDa |
RHOBTB3 | Rho-related BTB domain containing 3 |
RRM2 | ribonucleotide reductase M2 |
SCD | stearoyl-CoA desaturase (delta-9-desaturase) |
SCGB1D2 | secretoglobin, family 1D, member 2 |
SCNN1A | sodium channel, non voltage gated 1 alpha subunit |
SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 |
SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 |
SH3BGRL | SH3 domain binding glutamate-rich protein like |
SLC39A6 | solute carrier family 39 (zinc transporter), member 6 |
SORL1 | sortilin-related receptor, L(DLR class) A repeats containing |
SPDEF | SAM pointed domain containing ETS transcription factor |
SRPX | sushi-repeat containing protein, X-linked |
STMN1 | stathmin 1 |
TFF1 | trefoil factor 1 |
TFF3 | trefoil factor 3 (intestinal) |
TFPI2 | tissue factor pathway inhibitor 2 |
THBS1 | thrombospondin 1 |
TMEM50A | transmembrane protein 50A |
TOP2A | topoisomerase (DNA) II alpha 170kDa |
TUBA1A | tubulin, alpha 1a |
TUBB | tubulin, beta class I |
TYMS | thymidylate synthetase |