BRD-A58048407_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

60 genes differentially expressed following the BRD-A58048407_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5
ADCK3 aarF domain containing kinase 3
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
ANK2 ankyrin 2, neuronal
CD24 CD24 molecule
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CLDN18 claudin 18
CTSE cathepsin E
CXCL8 chemokine (C-X-C motif) ligand 8
DUOX2 dual oxidase 2
FABP4 fatty acid binding protein 4, adipocyte
FCN1 ficolin (collagen/fibrinogen domain containing) 1
FKBP11 FK506 binding protein 11, 19 kDa
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
GDF15 growth differentiation factor 15
GOLM1 golgi membrane protein 1
GPRC5A G protein-coupled receptor, class C, group 5, member A
HBB hemoglobin, beta
HMOX1 heme oxygenase 1
HOPX HOP homeobox
IGHM immunoglobulin heavy constant mu
LMO2 LIM domain only 2 (rhombotin-like 1)
LRP4 low density lipoprotein receptor-related protein 4
MIR22HG MIR22 host gene
PGC progastricsin (pepsinogen C)
S100P S100 calcium binding protein P
SFRP1 secreted frizzled-related protein 1
SLC27A3 solute carrier family 27 (fatty acid transporter), member 3
SLC39A14 solute carrier family 39 (zinc transporter), member 14
SORD sorbitol dehydrogenase
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TECR trans-2,3-enoyl-CoA reductase
TFF3 trefoil factor 3 (intestinal)
UPF3A UPF3 regulator of nonsense transcripts homolog A (yeast)
ZDHHC11 zinc finger, DHHC-type containing 11

decreased expression

Symbol Name
ASS1 argininosuccinate synthase 1
C1QA complement component 1, q subcomponent, A chain
CARD10 caspase recruitment domain family, member 10
CCL8 chemokine (C-C motif) ligand 8
CHST1 carbohydrate (keratan sulfate Gal-6) sulfotransferase 1
DNTTIP2 deoxynucleotidyltransferase, terminal, interacting protein 2
GATA3 GATA binding protein 3
HSPA8 heat shock 70kDa protein 8
IDO1 indoleamine 2,3-dioxygenase 1
KRT14 keratin 14, type I
KRT18 keratin 18, type I
KRT23 keratin 23, type I
LY6E lymphocyte antigen 6 complex, locus E
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
NMU neuromedin U
PFN2 profilin 2
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
TDO2 tryptophan 2,3-dioxygenase
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
ZNF331 zinc finger protein 331
ZNF91 zinc finger protein 91
Funding