BRD-A58280226_Y-27632_MCF7_24_h_10_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

58 genes differentially expressed following the BRD-A58280226_Y-27632_MCF7_24_h_10_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AIM2 absent in melanoma 2
ANO1 anoctamin 1, calcium activated chloride channel
ANXA5 annexin A5
BGN biglycan
CDC25A cell division cycle 25A
CTSH cathepsin H
CXCL13 chemokine (C-X-C motif) ligand 13
CXCL14 chemokine (C-X-C motif) ligand 14
DACH1 dachshund family transcription factor 1
ERG v-ets avian erythroblastosis virus E26 oncogene homolog
GSN gelsolin
HSPB8 heat shock 22kDa protein 8
KANK1 KN motif and ankyrin repeat domains 1
MEF2C myocyte enhancer factor 2C
NDRG1 N-myc downstream regulated 1
NFIB nuclear factor I/B
PAM peptidylglycine alpha-amidating monooxygenase
PODXL podocalyxin-like
RHOB ras homolog family member B
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast)
TYMS thymidylate synthetase
VDAC1 voltage-dependent anion channel 1

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABAT 4-aminobutyrate aminotransferase
ADD3 adducin 3 (gamma)
ANPEP alanyl (membrane) aminopeptidase
ANXA1 annexin A1
AQP3 aquaporin 3 (Gill blood group)
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2
BLNK B-cell linker
BTG1 B-cell translocation gene 1, anti-proliferative
BTG2 BTG family, member 2
C1ORF106 chromosome 1 open reading frame 106
C6ORF62 chromosome 6 open reading frame 62
CD44 CD44 molecule (Indian blood group)
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
CXCL2 chemokine (C-X-C motif) ligand 2
CYCS cytochrome c, somatic
EHF ets homologous factor
EPAS1 endothelial PAS domain protein 1
FAM69A family with sequence similarity 69, member A
H2BFS H2B histone family, member S (pseudogene)
HIST1H1C histone cluster 1, H1c
HIST1H2AC histone cluster 1, H2ac
HN1 hematological and neurological expressed 1
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
LITAF lipopolysaccharide-induced TNF factor
MARCKS myristoylated alanine-rich protein kinase C substrate
NLGN4X neuroligin 4, X-linked
PDLIM1 PDZ and LIM domain 1
PID1 phosphotyrosine interaction domain containing 1
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
RGCC regulator of cell cycle
SCG2 secretogranin II
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
TAX1BP3 Tax1 (human T-cell leukemia virus type I) binding protein 3
TWF1 twinfilin actin binding protein 1