| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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122 genes differentially expressed following the BRD-A58767537_afatinib_SKBR3_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ABCG1 | ATP-binding cassette, sub-family G (WHITE), member 1 |
| ADM | adrenomedullin |
| ADRB2 | adrenoceptor beta 2, surface |
| AKAP9 | A kinase (PRKA) anchor protein 9 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 |
| ATP2A3 | ATPase, Ca++ transporting, ubiquitous |
| ATP9A | ATPase, class II, type 9A |
| C3AR1 | complement component 3a receptor 1 |
| CA4 | carbonic anhydrase IV |
| CAPN1 | calpain 1, (mu/I) large subunit |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) |
| CD9 | CD9 molecule |
| CERK | ceramide kinase |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 |
| CLIC5 | chloride intracellular channel 5 |
| CPA3 | carboxypeptidase A3 (mast cell) |
| CPM | carboxypeptidase M |
| CTSS | cathepsin S |
| DEPTOR | DEP domain containing MTOR-interacting protein |
| ESR1 | estrogen receptor 1 |
| FAM129A | family with sequence similarity 129, member A |
| FHL1 | four and a half LIM domains 1 |
| GLUL | glutamate-ammonia ligase |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HBP1 | HMG-box transcription factor 1 |
| HECA | headcase homolog (Drosophila) |
| HP | haptoglobin |
| LOC100272216 | uncharacterized LOC100272216 |
| MPO | myeloperoxidase |
| MS4A4A | membrane-spanning 4-domains, subfamily A, member 4A |
| MVP | major vault protein |
| OBSL1 | obscurin-like 1 |
| PDCD4 | programmed cell death 4 (neoplastic transformation inhibitor) |
| PLTP | phospholipid transfer protein |
| PPAP2C | phosphatidic acid phosphatase type 2C |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 |
| SDCBP | syndecan binding protein (syntenin) |
| SELENBP1 | selenium binding protein 1 |
| SLC35E2B | solute carrier family 35, member E2B |
| SPDEF | SAM pointed domain containing ETS transcription factor |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) |
| STC2 | stanniocalcin 2 |
| STOM | stomatin |
| SULT1A1 | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 |
| TFAP2A | transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) |
| TPP1 | tripeptidyl peptidase I |
| TPSAB1 | tryptase alpha/beta 1 |
| TRIM2 | tripartite motif containing 2 |
| TSC22D1 | TSC22 domain family, member 1 |
| TXNIP | thioredoxin interacting protein |
| USP9X | ubiquitin specific peptidase 9, X-linked |
| VPS28 | vacuolar protein sorting 28 homolog (S. cerevisiae) |
| XBP1 | X-box binding protein 1 |
| YPEL5 | yippee-like 5 (Drosophila) |
| ZNF551 | zinc finger protein 551 |
| ZSCAN18 | zinc finger and SCAN domain containing 18 |
| Symbol | Name |
|---|---|
| ABAT | 4-aminobutyrate aminotransferase |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) |
| ARPP19 | cAMP-regulated phosphoprotein, 19kDa |
| ASF1B | anti-silencing function 1B histone chaperone |
| AURKA | aurora kinase A |
| BIRC5 | baculoviral IAP repeat containing 5 |
| CCNA2 | cyclin A2 |
| CD24 | CD24 molecule |
| CDC25A | cell division cycle 25A |
| CDC42 | cell division cycle 42 |
| CDK1 | cyclin-dependent kinase 1 |
| CEP55 | centrosomal protein 55kDa |
| CKS2 | CDC28 protein kinase regulatory subunit 2 |
| CRYAB | crystallin, alpha B |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) |
| CSTA | cystatin A (stefin A) |
| CXCL14 | chemokine (C-X-C motif) ligand 14 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| EGR2 | early growth response 2 |
| EIF5 | eukaryotic translation initiation factor 5 |
| FABP7 | fatty acid binding protein 7, brain |
| FN1 | fibronectin 1 |
| GAL | galanin/GMAP prepropeptide |
| GBP1 | guanylate binding protein 1, interferon-inducible |
| GINS2 | GINS complex subunit 2 (Psf2 homolog) |
| GPX3 | glutathione peroxidase 3 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
| HN1 | hematological and neurological expressed 1 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 |
| IL1RN | interleukin 1 receptor antagonist |
| KIF20A | kinesin family member 20A |
| KRT14 | keratin 14, type I |
| KRT5 | keratin 5, type II |
| KRT6A | keratin 6A, type II |
| KRT6B | keratin 6B, type II |
| LMO3 | LIM domain only 3 (rhombotin-like 2) |
| MAL | mal, T-cell differentiation protein |
| MELK | maternal embryonic leucine zipper kinase |
| MSMO1 | methylsterol monooxygenase 1 |
| MYBL2 | v-myb avian myeloblastosis viral oncogene homolog-like 2 |
| MYBPC1 | myosin binding protein C, slow type |
| NEB | nebulin |
| NR2F6 | nuclear receptor subfamily 2, group F, member 6 |
| NUP85 | nucleoporin 85kDa |
| PCDH9 | protocadherin 9 |
| PITX1 | paired-like homeodomain 1 |
| PLK1 | polo-like kinase 1 |
| PNP | purine nucleoside phosphorylase |
| POSTN | periostin, osteoblast specific factor |
| RRM2 | ribonucleotide reductase M2 |
| S100A2 | S100 calcium binding protein A2 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) |
| SCG2 | secretogranin II |
| SIVA1 | SIVA1, apoptosis-inducing factor |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 |
| SRSF7 | serine/arginine-rich splicing factor 7 |
| STMN1 | stathmin 1 |
| TACC3 | transforming, acidic coiled-coil containing protein 3 |
| TMEM38B | transmembrane protein 38B |
| TRIP13 | thyroid hormone receptor interactor 13 |
| TTN | titin |
| UBE2C | ubiquitin-conjugating enzyme E2C |
| UBE2S | ubiquitin-conjugating enzyme E2S |
| YKT6 | YKT6 v-SNARE homolog (S. cerevisiae) |
