BRD-A58767537_afatinib_SKBR3_3_h_0.37_um Gene Set
Genes
55 genes differentially expressed following the BRD-A58767537_afatinib_SKBR3_3_h_0.37_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
increased expression
| Symbol |
Name |
|
1060P11.3
|
killer cell immunoglobulin-like receptor, three domains, pseudogene
|
|
ANPEP
|
alanyl (membrane) aminopeptidase
|
|
AZGP1
|
alpha-2-glycoprotein 1, zinc-binding
|
|
BTG1
|
B-cell translocation gene 1, anti-proliferative
|
|
CCND2
|
cyclin D2
|
|
CD44
|
CD44 molecule (Indian blood group)
|
|
CDH1
|
cadherin 1, type 1, E-cadherin (epithelial)
|
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
|
DDIT4
|
DNA-damage-inducible transcript 4
|
|
ENPP2
|
ectonucleotide pyrophosphatase/phosphodiesterase 2
|
|
FAM129A
|
family with sequence similarity 129, member A
|
|
FGFR3
|
fibroblast growth factor receptor 3
|
|
FOLR1
|
folate receptor 1 (adult)
|
|
GPM6B
|
glycoprotein M6B
|
|
HMG20B
|
high mobility group 20B
|
|
HOXA5
|
homeobox A5
|
|
HSPA1A
|
heat shock 70kDa protein 1A
|
|
IL7R
|
interleukin 7 receptor
|
|
ISG20
|
interferon stimulated exonuclease gene 20kDa
|
|
KIAA0355
|
KIAA0355
|
|
KIAA1033
|
KIAA1033
|
|
KRT15
|
keratin 15, type I
|
|
LITAF
|
lipopolysaccharide-induced TNF factor
|
|
MAP7
|
microtubule-associated protein 7
|
|
MDFIC
|
MyoD family inhibitor domain containing
|
|
METTL7A
|
methyltransferase like 7A
|
|
MSLN
|
mesothelin
|
|
NEBL
|
nebulette
|
|
PEBP1
|
phosphatidylethanolamine binding protein 1
|
|
PPIB
|
peptidylprolyl isomerase B (cyclophilin B)
|
|
SMC1A
|
structural maintenance of chromosomes 1A
|
|
TFF3
|
trefoil factor 3 (intestinal)
|
|
TSC22D3
|
TSC22 domain family, member 3
|
decreased expression
| Symbol |
Name |
|
AMIGO2
|
adhesion molecule with Ig-like domain 2
|
|
BGN
|
biglycan
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
|
CCNE2
|
cyclin E2
|
|
CHN2
|
chimerin 2
|
|
CXCL8
|
chemokine (C-X-C motif) ligand 8
|
|
DLX2
|
distal-less homeobox 2
|
|
DUSP7
|
dual specificity phosphatase 7
|
|
EGLN3
|
egl-9 family hypoxia-inducible factor 3
|
|
ENOPH1
|
enolase-phosphatase 1
|
|
GJA1
|
gap junction protein, alpha 1, 43kDa
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
|
MSMO1
|
methylsterol monooxygenase 1
|
|
MXRA7
|
matrix-remodelling associated 7
|
|
NFATC3
|
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
|
|
NKX3-1
|
NK3 homeobox 1
|
|
PRPF4
|
pre-mRNA processing factor 4
|
|
PTGS2
|
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
|
|
SPOCK1
|
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
|
|
STK39
|
serine threonine kinase 39
|
|
TGFB1
|
transforming growth factor, beta 1
|
|
TLR4
|
toll-like receptor 4
|
