BRD-A59174698_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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27 genes differentially expressed following the BRD-A59174698_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
CKS2 CDC28 protein kinase regulatory subunit 2
CSTA cystatin A (stefin A)
EFNB2 ephrin-B2
EMP1 epithelial membrane protein 1
GLRX glutaredoxin (thioltransferase)
HIST1H1C histone cluster 1, H1c
IQCG IQ motif containing G
KCNS3 potassium voltage-gated channel, modifier subfamily S, member 3
MME membrane metallo-endopeptidase
MNDA myeloid cell nuclear differentiation antigen
MT1M metallothionein 1M
NNMT nicotinamide N-methyltransferase
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SCPEP1 serine carboxypeptidase 1
SFRP4 secreted frizzled-related protein 4
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SRSF7 serine/arginine-rich splicing factor 7
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TPD52 tumor protein D52

decreased expression

Symbol Name
BAX BCL2-associated X protein
DDAH1 dimethylarginine dimethylaminohydrolase 1
FHL1 four and a half LIM domains 1
GPX3 glutathione peroxidase 3
IGHM immunoglobulin heavy constant mu
NFIB nuclear factor I/B
ZNF423 zinc finger protein 423