Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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158 genes differentially expressed following the BRD-A60245366_AS-601245_A549_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
ACTC1 | actin, alpha, cardiac muscle 1 |
ADAMTS5 | ADAM metallopeptidase with thrombospondin type 1 motif, 5 |
ALDH3A2 | aldehyde dehydrogenase 3 family, member A2 |
ALOX5AP | arachidonate 5-lipoxygenase-activating protein |
AQP3 | aquaporin 3 (Gill blood group) |
ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 |
ATHL1 | ATH1, acid trehalase-like 1 (yeast) |
AUTS2 | autism susceptibility candidate 2 |
AZGP1 | alpha-2-glycoprotein 1, zinc-binding |
BHLHE40 | basic helix-loop-helix family, member e40 |
BPGM | 2,3-bisphosphoglycerate mutase |
CA12 | carbonic anhydrase XII |
CCL5 | chemokine (C-C motif) ligand 5 |
CD24 | CD24 molecule |
CD248 | CD248 molecule, endosialin |
CD48 | CD48 molecule |
CERK | ceramide kinase |
CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) |
CHODL | chondrolectin |
CHST2 | carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 |
CSTA | cystatin A (stefin A) |
CYB5A | cytochrome b5 type A (microsomal) |
DEFB1 | defensin, beta 1 |
EGR2 | early growth response 2 |
FAM3C | family with sequence similarity 3, member C |
FCER2 | Fc fragment of IgE, low affinity II, receptor for (CD23) |
FCMR | Fc fragment of IgM receptor |
FEZ1 | fasciculation and elongation protein zeta 1 (zygin I) |
FKBP11 | FK506 binding protein 11, 19 kDa |
FXYD3 | FXYD domain containing ion transport regulator 3 |
FXYD5 | FXYD domain containing ion transport regulator 5 |
FXYD6 | FXYD domain containing ion transport regulator 6 |
GATA3 | GATA binding protein 3 |
GCLC | glutamate-cysteine ligase, catalytic subunit |
GNLY | granulysin |
GSTA4 | glutathione S-transferase alpha 4 |
GYPC | glycophorin C (Gerbich blood group) |
HOPX | HOP homeobox |
HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) |
IGHA1 | immunoglobulin heavy constant alpha 1 |
IGHD | immunoglobulin heavy constant delta |
IL2RB | interleukin 2 receptor, beta |
IL32 | interleukin 32 |
ITGAM | integrin, alpha M (complement component 3 receptor 3 subunit) |
KRT17 | keratin 17, type I |
KRT6A | keratin 6A, type II |
KRT6B | keratin 6B, type II |
LBH | limb bud and heart development |
LSP1 | lymphocyte-specific protein 1 |
LSR | lipolysis stimulated lipoprotein receptor |
MAPKAPK2 | mitogen-activated protein kinase-activated protein kinase 2 |
MREG | melanoregulin |
NES | nestin |
NUP210 | nucleoporin 210kDa |
NXT2 | nuclear transport factor 2-like export factor 2 |
PRF1 | perforin 1 (pore forming protein) |
PRR5 | proline rich 5 (renal) |
PTN | pleiotrophin |
RBP1 | retinol binding protein 1, cellular |
RCAN2 | regulator of calcineurin 2 |
RORA | RAR-related orphan receptor A |
RUNX3 | runt-related transcription factor 3 |
S100A2 | S100 calcium binding protein A2 |
SEPP1 | selenoprotein P, plasma, 1 |
SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 |
SERPINI1 | serpin peptidase inhibitor, clade I (neuroserpin), member 1 |
SFN | stratifin |
SFTPB | surfactant protein B |
SLAMF1 | signaling lymphocytic activation molecule family member 1 |
SPRR1B | small proline-rich protein 1B |
STK26 | serine/threonine protein kinase 26 |
TBX2 | T-box 2 |
TDO2 | tryptophan 2,3-dioxygenase |
TMEM45A | transmembrane protein 45A |
TMSB15A | thymosin beta 15a |
TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 |
TPST2 | tyrosylprotein sulfotransferase 2 |
TRAC | T cell receptor alpha constant |
VEGFA | vascular endothelial growth factor A |
VPS45 | vacuolar protein sorting 45 homolog (S. cerevisiae) |
Symbol | Name |
---|---|
ACTR2 | ARP2 actin-related protein 2 homolog (yeast) |
ADRB2 | adrenoceptor beta 2, surface |
ANXA1 | annexin A1 |
ARHGAP29 | Rho GTPase activating protein 29 |
AXL | AXL receptor tyrosine kinase |
BMP2 | bone morphogenetic protein 2 |
BRCA1 | breast cancer 1, early onset |
CAB39 | calcium binding protein 39 |
CCP110 | centriolar coiled coil protein 110kDa |
CD9 | CD9 molecule |
CFD | complement factor D (adipsin) |
CILP | cartilage intermediate layer protein, nucleotide pyrophosphohydrolase |
CLU | clusterin |
CPE | carboxypeptidase E |
CTGF | connective tissue growth factor |
CTSZ | cathepsin Z |
CYR61 | cysteine-rich, angiogenic inducer, 61 |
DUSP3 | dual specificity phosphatase 3 |
ENPP1 | ectonucleotide pyrophosphatase/phosphodiesterase 1 |
ESR1 | estrogen receptor 1 |
FABP4 | fatty acid binding protein 4, adipocyte |
FEZ2 | fasciculation and elongation protein zeta 2 (zygin II) |
FGFR2 | fibroblast growth factor receptor 2 |
FKBP5 | FK506 binding protein 5 |
FZD6 | frizzled class receptor 6 |
G0S2 | G0/G1 switch 2 |
GABBR2 | gamma-aminobutyric acid (GABA) B receptor, 2 |
GLIPR1 | GLI pathogenesis-related 1 |
GNAQ | guanine nucleotide binding protein (G protein), q polypeptide |
HIST1H2BG | histone cluster 1, H2bg |
HSPH1 | heat shock 105kDa/110kDa protein 1 |
HTRA1 | HtrA serine peptidase 1 |
IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial |
IFRD2 | interferon-related developmental regulator 2 |
IGF1R | insulin-like growth factor 1 receptor |
IGFBP7 | insulin-like growth factor binding protein 7 |
KIF1BP | KIF1 binding protein |
LOXL2 | lysyl oxidase-like 2 |
LXN | latexin |
LYZ | lysozyme |
MBNL1 | muscleblind-like splicing regulator 1 |
MT1M | metallothionein 1M |
MTUS1 | microtubule associated tumor suppressor 1 |
NET1 | neuroepithelial cell transforming 1 |
NGRN | neugrin, neurite outgrowth associated |
NKTR | natural killer cell triggering receptor |
NOLC1 | nucleolar and coiled-body phosphoprotein 1 |
NRCAM | neuronal cell adhesion molecule |
NT5E | 5'-nucleotidase, ecto (CD73) |
NUP93 | nucleoporin 93kDa |
PLN | phospholamban |
PROM1 | prominin 1 |
PRRC2C | proline-rich coiled-coil 2C |
PTPRC | protein tyrosine phosphatase, receptor type, C |
PXDN | peroxidasin |
RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 |
RASA4 | RAS p21 protein activator 4 |
RGS5 | regulator of G-protein signaling 5 |
S100P | S100 calcium binding protein P |
SERINC3 | serine incorporator 3 |
SFRP1 | secreted frizzled-related protein 1 |
SGK1 | serum/glucocorticoid regulated kinase 1 |
SH3BP5 | SH3-domain binding protein 5 (BTK-associated) |
SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 |
SRRM2 | serine/arginine repetitive matrix 2 |
STAU1 | staufen double-stranded RNA binding protein 1 |
TFDP1 | transcription factor Dp-1 |
TFPI2 | tissue factor pathway inhibitor 2 |
TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) |
THBD | thrombomodulin |
THBS1 | thrombospondin 1 |
TMBIM1 | transmembrane BAX inhibitor motif containing 1 |
VANGL1 | VANGL planar cell polarity protein 1 |
VWF | von Willebrand factor |
YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta |
ZBTB16 | zinc finger and BTB domain containing 16 |
ZNF423 | zinc finger protein 423 |