Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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81 genes differentially expressed following the BRD-A60245366_AS-601245_SKBR3_3_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
AKR1C2 | aldo-keto reductase family 1, member C2 |
ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 |
ALDH2 | aldehyde dehydrogenase 2 family (mitochondrial) |
ASRGL1 | asparaginase like 1 |
CA12 | carbonic anhydrase XII |
CCT2 | chaperonin containing TCP1, subunit 2 (beta) |
CEMIP | cell migration inducing protein, hyaluronan binding |
CHST2 | carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 |
CPS1 | carbamoyl-phosphate synthase 1, mitochondrial |
CRABP2 | cellular retinoic acid binding protein 2 |
CXCR4 | chemokine (C-X-C motif) receptor 4 |
CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 |
ENO1 | enolase 1, (alpha) |
FOLR1 | folate receptor 1 (adult) |
GPER1 | G protein-coupled estrogen receptor 1 |
HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 |
HOOK2 | hook microtubule-tethering protein 2 |
IL1R1 | interleukin 1 receptor, type I |
IMPA2 | inositol(myo)-1(or 4)-monophosphatase 2 |
KYNU | kynureninase |
LTF | lactotransferrin |
MPPED2 | metallophosphoesterase domain containing 2 |
MSX1 | msh homeobox 1 |
NQO1 | NAD(P)H dehydrogenase, quinone 1 |
OLFML2A | olfactomedin-like 2A |
PITX1 | paired-like homeodomain 1 |
SEPP1 | selenoprotein P, plasma, 1 |
SGK1 | serum/glucocorticoid regulated kinase 1 |
SST | somatostatin |
TIMP3 | TIMP metallopeptidase inhibitor 3 |
TIPARP | TCDD-inducible poly(ADP-ribose) polymerase |
UCP2 | uncoupling protein 2 (mitochondrial, proton carrier) |
VAMP8 | vesicle-associated membrane protein 8 |
VIM | vimentin |
XIST | X inactive specific transcript (non-protein coding) |
Symbol | Name |
---|---|
ADRB2 | adrenoceptor beta 2, surface |
AKAP12 | A kinase (PRKA) anchor protein 12 |
BACE2 | beta-site APP-cleaving enzyme 2 |
BCHE | butyrylcholinesterase |
CCL5 | chemokine (C-C motif) ligand 5 |
CD200 | CD200 molecule |
CD24 | CD24 molecule |
CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 |
CLIC5 | chloride intracellular channel 5 |
COL14A1 | collagen, type XIV, alpha 1 |
CPB1 | carboxypeptidase B1 (tissue) |
CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) |
CST7 | cystatin F (leukocystatin) |
CTSW | cathepsin W |
CYTL1 | cytokine-like 1 |
DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked |
EIF1AY | eukaryotic translation initiation factor 1A, Y-linked |
ERAP2 | endoplasmic reticulum aminopeptidase 2 |
FAM129A | family with sequence similarity 129, member A |
FAS | Fas cell surface death receptor |
FGFR2 | fibroblast growth factor receptor 2 |
GDF15 | growth differentiation factor 15 |
GNAI1 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 |
GREM1 | gremlin 1, DAN family BMP antagonist |
GZMK | granzyme K (granzyme 3; tryptase II) |
HSPA2 | heat shock 70kDa protein 2 |
IGFBP7 | insulin-like growth factor binding protein 7 |
JADE2 | jade family PHD finger 2 |
KANK1 | KN motif and ankyrin repeat domains 1 |
KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 |
KDM5D | lysine (K)-specific demethylase 5D |
MMP9 | matrix metallopeptidase 9 |
MRPS30 | mitochondrial ribosomal protein S30 |
MTSS1 | metastasis suppressor 1 |
MYLK | myosin light chain kinase |
NT5E | 5'-nucleotidase, ecto (CD73) |
PDLIM5 | PDZ and LIM domain 5 |
PTGER4 | prostaglandin E receptor 4 (subtype EP4) |
RGS1 | regulator of G-protein signaling 1 |
RPS4Y1 | ribosomal protein S4, Y-linked 1 |
SPP1 | secreted phosphoprotein 1 |
STK39 | serine threonine kinase 39 |
SULF1 | sulfatase 1 |
TOB1 | transducer of ERBB2, 1 |
ZBTB16 | zinc finger and BTB domain containing 16 |
ZNF281 | zinc finger protein 281 |