BRD-A62035778_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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28 genes differentially expressed following the BRD-A62035778_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17
DEGS1 delta(4)-desaturase, sphingolipid 1
GDF15 growth differentiation factor 15
HIST1H1C histone cluster 1, H1c
IGFBP5 insulin-like growth factor binding protein 5
KRT23 keratin 23, type I
NPY1R neuropeptide Y receptor Y1
PECR peroxisomal trans-2-enoyl-CoA reductase
RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis)
REG1B regenerating islet-derived 1 beta
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
TCF4 transcription factor 4
TXNDC9 thioredoxin domain containing 9
UGCG UDP-glucose ceramide glucosyltransferase

decreased expression

Symbol Name
CD14 CD14 molecule
COL4A1 collagen, type IV, alpha 1
DHRS3 dehydrogenase/reductase (SDR family) member 3
ENO1 enolase 1, (alpha)
FPGS folylpolyglutamate synthase
HSPD1 heat shock 60kDa protein 1 (chaperonin)
IFRD2 interferon-related developmental regulator 2
MMP9 matrix metallopeptidase 9
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)
PRKCD protein kinase C, delta
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
SPRED2 sprouty-related, EVH1 domain containing 2
TPM4 tropomyosin 4