BRD-A63583287_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

101 genes differentially expressed following the BRD-A63583287_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ARC activity-regulated cytoskeleton-associated protein
CCDC92 coiled-coil domain containing 92
CD163 CD163 molecule
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
COL1A1 collagen, type I, alpha 1
DCN decorin
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
FOXG1 forkhead box G1
GADD45A growth arrest and DNA-damage-inducible, alpha
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HMOX1 heme oxygenase 1
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPH1 heat shock 105kDa/110kDa protein 1
IER5 immediate early response 5
IFRD1 interferon-related developmental regulator 1
JUN jun proto-oncogene
JUNB jun B proto-oncogene
LTB lymphotoxin beta (TNF superfamily, member 3)
MAN1A1 mannosidase, alpha, class 1A, member 1
MEF2C myocyte enhancer factor 2C
MT1M metallothionein 1M
MUC5B mucin 5B, oligomeric mucus/gel-forming
NCOA3 nuclear receptor coactivator 3
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PKIA protein kinase (cAMP-dependent, catalytic) inhibitor alpha
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PPM1D protein phosphatase, Mg2+/Mn2+ dependent, 1D
PPP1R15A protein phosphatase 1, regulatory subunit 15A
SAT1 spermidine/spermine N1-acetyltransferase 1
SQSTM1 sequestosome 1
STAR steroidogenic acute regulatory protein
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
TXNL4B thioredoxin-like 4B
TXNRD1 thioredoxin reductase 1
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
ZFP36 ZFP36 ring finger protein

decreased expression

Symbol Name
ACP6 acid phosphatase 6, lysophosphatidic
ADGRG6 adhesion G protein-coupled receptor G6
ALCAM activated leukocyte cell adhesion molecule
ANXA3 annexin A3
AREG amphiregulin
ARHGAP29 Rho GTPase activating protein 29
ATP6V0E1 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1
AURKA aurora kinase A
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
CCND1 cyclin D1
CCNF cyclin F
CD59 CD59 molecule, complement regulatory protein
CDC25B cell division cycle 25B
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
CENPA centromere protein A
CHRDL1 chordin-like 1
DKK1 dickkopf WNT signaling pathway inhibitor 1
DLGAP5 discs, large (Drosophila) homolog-associated protein 5
ERBB3 erb-b2 receptor tyrosine kinase 3
EREG epiregulin
EXOSC4 exosome component 4
GPRC5A G protein-coupled receptor, class C, group 5, member A
H1F0 H1 histone family, member 0
HEATR1 HEAT repeat containing 1
HMGA2 high mobility group AT-hook 2
IER3 immediate early response 3
IFITM3 interferon induced transmembrane protein 3
IGF1R insulin-like growth factor 1 receptor
IGFBP3 insulin-like growth factor binding protein 3
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
JADE2 jade family PHD finger 2
KANK1 KN motif and ankyrin repeat domains 1
KLF9 Kruppel-like factor 9
LPL lipoprotein lipase
MAGEA12 melanoma antigen family A12
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
MGLL monoglyceride lipase
MOK MOK protein kinase
MX2 MX dynamin-like GTPase 2
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2
NFIB nuclear factor I/B
PLA2G16 phospholipase A2, group XVI
PLK1 polo-like kinase 1
PPAP2C phosphatidic acid phosphatase type 2C
PRSS23 protease, serine, 23
RPL27A ribosomal protein L27a
RPS11 ribosomal protein S11
SMAD3 SMAD family member 3
SORD sorbitol dehydrogenase
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SPRY2 sprouty homolog 2 (Drosophila)
SYNM synemin, intermediate filament protein
THBS1 thrombospondin 1
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TM4SF1 transmembrane 4 L six family member 1
TMEM185B transmembrane protein 185B
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TOP2A topoisomerase (DNA) II alpha 170kDa
TSEN2 TSEN2 tRNA splicing endonuclease subunit
WWTR1 WW domain containing transcription regulator 1