BRD-A63583287_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

59 genes differentially expressed following the BRD-A63583287_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABHD4 abhydrolase domain containing 4
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
ASNS asparagine synthetase (glutamine-hydrolyzing)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CRISP3 cysteine-rich secretory protein 3
CSTA cystatin A (stefin A)
DDIT4 DNA-damage-inducible transcript 4
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
FOSL1 FOS-like antigen 1
GABRE gamma-aminobutyric acid (GABA) A receptor, epsilon
GADD45A growth arrest and DNA-damage-inducible, alpha
GULP1 GULP, engulfment adaptor PTB domain containing 1
HBB hemoglobin, beta
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPH1 heat shock 105kDa/110kDa protein 1
IER5 immediate early response 5
KRT13 keratin 13, type I
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
NQO1 NAD(P)H dehydrogenase, quinone 1
PIR pirin (iron-binding nuclear protein)
PROM1 prominin 1
PSAT1 phosphoserine aminotransferase 1
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SERTAD2 SERTA domain containing 2
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SPRR3 small proline-rich protein 3
SRGN serglycin
TXNRD1 thioredoxin reductase 1
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
WNT5A wingless-type MMTV integration site family, member 5A

decreased expression

Symbol Name
ALCAM activated leukocyte cell adhesion molecule
ARHGAP29 Rho GTPase activating protein 29
BAMBI BMP and activin membrane-bound inhibitor
CA12 carbonic anhydrase XII
CCNE2 cyclin E2
CXCL14 chemokine (C-X-C motif) ligand 14
GATA3 GATA binding protein 3
GBP1 guanylate binding protein 1, interferon-inducible
GJA1 gap junction protein, alpha 1, 43kDa
HES1 hes family bHLH transcription factor 1
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
KRT14 keratin 14, type I
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
MFAP5 microfibrillar associated protein 5
NFIB nuclear factor I/B
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
POSTN periostin, osteoblast specific factor
PRDX2 peroxiredoxin 2
RSRP1 arginine/serine-rich protein 1
SOX4 SRY (sex determining region Y)-box 4
TNIK TRAF2 and NCK interacting kinase
Funding