BRD-A63836183_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

71 genes differentially expressed following the BRD-A63836183_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
A2M alpha-2-macroglobulin
AIM1 absent in melanoma 1
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha
CA2 carbonic anhydrase II
CAST calpastatin
CD44 CD44 molecule (Indian blood group)
CD9 CD9 molecule
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
CPA3 carboxypeptidase A3 (mast cell)
DENND1B DENN/MADD domain containing 1B
DPYD dihydropyrimidine dehydrogenase
EFNA1 ephrin-A1
EMP1 epithelial membrane protein 1
ENC1 ectodermal-neural cortex 1 (with BTB domain)
EVI2A ecotropic viral integration site 2A
EZR ezrin
FAM129A family with sequence similarity 129, member A
FN1 fibronectin 1
FST follistatin
GJA1 gap junction protein, alpha 1, 43kDa
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
IL7R interleukin 7 receptor
KLF9 Kruppel-like factor 9
LPAR6 lysophosphatidic acid receptor 6
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PEG10 paternally expressed 10
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)
RAD21 RAD21 homolog (S. pombe)
RIN2 Ras and Rab interactor 2
SGCE sarcoglycan, epsilon
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SPON1 spondin 1, extracellular matrix protein
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
TPSAB1 tryptase alpha/beta 1
TPSB2 tryptase beta 2 (gene/pseudogene)
VPS72 vacuolar protein sorting 72 homolog (S. cerevisiae)
XIST X inactive specific transcript (non-protein coding)

decreased expression

Symbol Name
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3
AGR2 anterior gradient 2
ALCAM activated leukocyte cell adhesion molecule
AP2M1 adaptor-related protein complex 2, mu 1 subunit
ATP6AP1 ATPase, H+ transporting, lysosomal accessory protein 1
BSCL2 Berardinelli-Seip congenital lipodystrophy 2 (seipin)
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
FADS1 fatty acid desaturase 1
G0S2 G0/G1 switch 2
GALNT10 polypeptide N-acetylgalactosaminyltransferase 10
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12
GARS glycyl-tRNA synthetase
GRN granulin
HOOK2 hook microtubule-tethering protein 2
HOXC6 homeobox C6
HSPA1A heat shock 70kDa protein 1A
HSPB8 heat shock 22kDa protein 8
IGFBP6 insulin-like growth factor binding protein 6
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
MCOLN1 mucolipin 1
NDN necdin, melanoma antigen (MAGE) family member
NUP210 nucleoporin 210kDa
OXTR oxytocin receptor
PLCB4 phospholipase C, beta 4
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
SIDT2 SID1 transmembrane family, member 2
SLC39A6 solute carrier family 39 (zinc transporter), member 6
SPTAN1 spectrin, alpha, non-erythrocytic 1
TFF1 trefoil factor 1
TFF3 trefoil factor 3 (intestinal)
UBE2S ubiquitin-conjugating enzyme E2S
VCAN versican