BRD-A65327625_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

32 genes differentially expressed following the BRD-A65327625_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ANPEP alanyl (membrane) aminopeptidase
BASP1 brain abundant, membrane attached signal protein 1
CD40 CD40 molecule, TNF receptor superfamily member 5
CSTA cystatin A (stefin A)
CXCL9 chemokine (C-X-C motif) ligand 9
EXT1 exostosin glycosyltransferase 1
FGFR2 fibroblast growth factor receptor 2
GALC galactosylceramidase
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
JUP junction plakoglobin
KCTD12 potassium channel tetramerization domain containing 12
PDZK1IP1 PDZK1 interacting protein 1
PPL periplakin
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
QPCT glutaminyl-peptide cyclotransferase
RTN1 reticulon 1
S100A8 S100 calcium binding protein A8
SFRP1 secreted frizzled-related protein 1
SLC27A3 solute carrier family 27 (fatty acid transporter), member 3
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACAT1 acetyl-CoA acetyltransferase 1
CDKN2A cyclin-dependent kinase inhibitor 2A
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase)
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase)
PEBP1 phosphatidylethanolamine binding protein 1
RPL37A ribosomal protein L37a
RPS11 ribosomal protein S11
SPATS2L spermatogenesis associated, serine-rich 2-like