BRD-A65767837_HYDROCORTISONE ACETATE_HCC515_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

122 genes differentially expressed following the BRD-A65767837_HYDROCORTISONE ACETATE_HCC515_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADRB2 adrenoceptor beta 2, surface
BIRC3 baculoviral IAP repeat containing 3
C10ORF10 chromosome 10 open reading frame 10
C3 complement component 3
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CERS6 ceramide synthase 6
CFB complement factor B
CXCL2 chemokine (C-X-C motif) ligand 2
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DCN decorin
DLG5 discs, large homolog 5 (Drosophila)
DLK1 delta-like 1 homolog (Drosophila)
DUSP1 dual specificity phosphatase 1
EXT1 exostosin glycosyltransferase 1
FBLN1 fibulin 1
FCGBP Fc fragment of IgG binding protein
FGFR3 fibroblast growth factor receptor 3
FKBP5 FK506 binding protein 5
FOSB FBJ murine osteosarcoma viral oncogene homolog B
GADD45B growth arrest and DNA-damage-inducible, beta
GJA1 gap junction protein, alpha 1, 43kDa
GLUL glutamate-ammonia ligase
GOLGA8A golgin A8 family, member A
HOMER2 homer scaffolding protein 2
HP haptoglobin
IFITM2 interferon induced transmembrane protein 2
KRT19 keratin 19, type I
KRT23 keratin 23, type I
KRT5 keratin 5, type II
LCN2 lipocalin 2
LTBP1 latent transforming growth factor beta binding protein 1
LTF lactotransferrin
MAOA monoamine oxidase A
MAOB monoamine oxidase B
MBNL2 muscleblind-like splicing regulator 2
MMP7 matrix metallopeptidase 7
MT1E metallothionein 1E
MT1F metallothionein 1F
MT1G metallothionein 1G
MT1H metallothionein 1H
MT1HL1 metallothionein 1H-like 1
MT1M metallothionein 1M
MT1X metallothionein 1X
MUC1 mucin 1, cell surface associated
NBPF10 neuroblastoma breakpoint family, member 10
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NNMT nicotinamide N-methyltransferase
NOTCH1 notch 1
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PDZK1IP1 PDZK1 interacting protein 1
PER1 period circadian clock 1
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PRR15L proline rich 15-like
PTPRC protein tyrosine phosphatase, receptor type, C
PXDN peroxidasin
RARRES3 retinoic acid receptor responder (tazarotene induced) 3
RIN2 Ras and Rab interactor 2
RTN3 reticulon 3
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SCGB2A1 secretoglobin, family 2A, member 1
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SIK1 salt-inducible kinase 1
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SLPI secretory leukocyte peptidase inhibitor
STAR steroidogenic acute regulatory protein
SYBU syntabulin (syntaxin-interacting)
TPD52L1 tumor protein D52-like 1
TSC22D3 TSC22 domain family, member 3
TXNIP thioredoxin interacting protein
VNN1 vanin 1
XK X-linked Kx blood group
ZBTB16 zinc finger and BTB domain containing 16
ZFP36 ZFP36 ring finger protein
ZFP36L2 ZFP36 ring finger protein-like 2

decreased expression

Symbol Name
AKIRIN1 akirin 1
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase)
ARL4C ADP-ribosylation factor-like 4C
ASCL1 achaete-scute family bHLH transcription factor 1
CADM1 cell adhesion molecule 1
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
COTL1 coactosin-like F-actin binding protein 1
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CSRP2 cysteine and glycine-rich protein 2
CXCL14 chemokine (C-X-C motif) ligand 14
DCBLD2 discoidin, CUB and LCCL domain containing 2
DLX2 distal-less homeobox 2
DUSP4 dual specificity phosphatase 4
FABP7 fatty acid binding protein 7, brain
FAM46A family with sequence similarity 46, member A
FGF13 fibroblast growth factor 13
FOSL1 FOS-like antigen 1
FOXG1 forkhead box G1
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
LGALS1 lectin, galactoside-binding, soluble, 1
NEFL neurofilament, light polypeptide
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2
NFIB nuclear factor I/B
NR2F1 nuclear receptor subfamily 2, group F, member 1
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
PHLDA1 pleckstrin homology-like domain, family A, member 1
PKIA protein kinase (cAMP-dependent, catalytic) inhibitor alpha
PRKACB protein kinase, cAMP-dependent, catalytic, beta
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SMARCA1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
STC1 stanniocalcin 1
SYT11 synaptotagmin XI
TBC1D31 TBC1 domain family, member 31
TGFBI transforming growth factor, beta-induced, 68kDa
TGOLN2 trans-golgi network protein 2
TMSB15A thymosin beta 15a
TUBB2B tubulin, beta 2B class IIb
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
ZMAT3 zinc finger, matrin-type 3
Funding