BRD-A70155556_NP-001236_HA1E_6.0_h_40.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

59 genes differentially expressed following the BRD-A70155556_NP-001236_HA1E_6.0_h_40.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C3 aldo-keto reductase family 1, member C3
APOC1 apolipoprotein C-I
ASNS asparagine synthetase (glutamine-hydrolyzing)
CXCL9 chemokine (C-X-C motif) ligand 9
FHL1 four and a half LIM domains 1
GCLM glutamate-cysteine ligase, modifier subunit
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
MAOA monoamine oxidase A
METTL7A methyltransferase like 7A
NQO1 NAD(P)H dehydrogenase, quinone 1
PPP1R3C protein phosphatase 1, regulatory subunit 3C
S100A8 S100 calcium binding protein A8
SCGB1D2 secretoglobin, family 1D, member 2
SCGB2A2 secretoglobin, family 2A, member 2
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SQSTM1 sequestosome 1
TRIB3 tribbles pseudokinase 3
TSC22D3 TSC22 domain family, member 3
TUSC3 tumor suppressor candidate 3
UGDH UDP-glucose 6-dehydrogenase

decreased expression

Symbol Name
C8ORF4 chromosome 8 open reading frame 4
CCND1 cyclin D1
COTL1 coactosin-like F-actin binding protein 1
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL8 chemokine (C-X-C motif) ligand 8
CYTH1 cytohesin 1
DEFB1 defensin, beta 1
DHRS11 dehydrogenase/reductase (SDR family) member 11
EGF epidermal growth factor
EGR2 early growth response 2
ELF1 E74-like factor 1 (ets domain transcription factor)
FHL2 four and a half LIM domains 2
GADD45B growth arrest and DNA-damage-inducible, beta
IGFBP3 insulin-like growth factor binding protein 3
LEF1 lymphoid enhancer-binding factor 1
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
MOK MOK protein kinase
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYLK myosin light chain kinase
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NRIP1 nuclear receptor interacting protein 1
NUP98 nucleoporin 98kDa
OLFM4 olfactomedin 4
PI3 peptidase inhibitor 3, skin-derived
PTN pleiotrophin
PTX3 pentraxin 3, long
QPCT glutaminyl-peptide cyclotransferase
RRP8 ribosomal RNA processing 8, methyltransferase, homolog (yeast)
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
SFRP1 secreted frizzled-related protein 1
SMAD3 SMAD family member 3
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TFF3 trefoil factor 3 (intestinal)
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
Funding