BRD-A70155556_NP-001236_THP1_6.0_h_40.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

73 genes differentially expressed following the BRD-A70155556_NP-001236_THP1_6.0_h_40.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACKR3 atypical chemokine receptor 3
ARHGAP1 Rho GTPase activating protein 1
ARL4C ADP-ribosylation factor-like 4C
C10ORF10 chromosome 10 open reading frame 10
CA12 carbonic anhydrase XII
CD24 CD24 molecule
CLEC3B C-type lectin domain family 3, member B
CREG1 cellular repressor of E1A-stimulated genes 1
DPYSL2 dihydropyrimidinase-like 2
DUSP1 dual specificity phosphatase 1
ECM1 extracellular matrix protein 1
EDN1 endothelin 1
EGLN3 egl-9 family hypoxia-inducible factor 3
ENPEP glutamyl aminopeptidase (aminopeptidase A)
ENPP4 ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative)
FAM69A family with sequence similarity 69, member A
FOS FBJ murine osteosarcoma viral oncogene homolog
FXYD6 FXYD domain containing ion transport regulator 6
GAS6 growth arrest-specific 6
GATA6 GATA binding protein 6
GREM1 gremlin 1, DAN family BMP antagonist
GSE1 Gse1 coiled-coil protein
HBB hemoglobin, beta
HIST1H1C histone cluster 1, H1c
HIST1H2BD histone cluster 1, H2bd
HSD17B6 hydroxysteroid (17-beta) dehydrogenase 6
HYOU1 hypoxia up-regulated 1
JUN jun proto-oncogene
MEST mesoderm specific transcript
NDUFA4L2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
NNMT nicotinamide N-methyltransferase
NPTX2 neuronal pentraxin II
P3H2 prolyl 3-hydroxylase 2
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PLIN2 perilipin 2
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PRUNE2 prune homolog 2 (Drosophila)
REEP1 receptor accessory protein 1
S100A8 S100 calcium binding protein A8
SCGB1D2 secretoglobin, family 1D, member 2
SCGB2A2 secretoglobin, family 2A, member 2
TES testin LIM domain protein
TMSB15A thymosin beta 15a
TRIM2 tripartite motif containing 2
TSC22D3 TSC22 domain family, member 3
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
ZNF395 zinc finger protein 395

decreased expression

Symbol Name
AKAP12 A kinase (PRKA) anchor protein 12
CHL1 cell adhesion molecule L1-like
EGR3 early growth response 3
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FOSL1 FOS-like antigen 1
GRWD1 glutamate-rich WD repeat containing 1
HOMER1 homer scaffolding protein 1
HS3ST1 heparan sulfate (glucosamine) 3-O-sulfotransferase 1
IGFBP7 insulin-like growth factor binding protein 7
KIAA0100 KIAA0100
LTF lactotransferrin
MRPS2 mitochondrial ribosomal protein S2
MXRA5 matrix-remodelling associated 5
MYC v-myc avian myelocytomatosis viral oncogene homolog
NME1 NME/NM23 nucleoside diphosphate kinase 1
NOLC1 nucleolar and coiled-body phosphoprotein 1
NOP16 NOP16 nucleolar protein
PRMT1 protein arginine methyltransferase 1
RPL36 ribosomal protein L36
RRP1B ribosomal RNA processing 1B
S100A7 S100 calcium binding protein A7
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
TGOLN2 trans-golgi network protein 2
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast)
TRAF4 TNF receptor-associated factor 4
Funding