BRD-A70649075_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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34 genes differentially expressed following the BRD-A70649075_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AGTR1 angiotensin II receptor, type 1
AKR1C3 aldo-keto reductase family 1, member C3
ARG2 arginase 2
AZGP1 alpha-2-glycoprotein 1, zinc-binding
CD58 CD58 molecule
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CHN2 chimerin 2
CPB1 carboxypeptidase B1 (tissue)
DPP4 dipeptidyl-peptidase 4
EVI2A ecotropic viral integration site 2A
GDF15 growth differentiation factor 15
LXN latexin
MAP7 microtubule-associated protein 7
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PROM1 prominin 1
PRSS2 protease, serine, 2 (trypsin 2)
QPCT glutaminyl-peptide cyclotransferase
SUB1 SUB1 homolog (S. cerevisiae)
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TPD52 tumor protein D52

decreased expression

Symbol Name
CSTA cystatin A (stefin A)
CTSG cathepsin G
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DLC1 DLC1 Rho GTPase activating protein
FOLR1 folate receptor 1 (adult)
FPGS folylpolyglutamate synthase
IL1RN interleukin 1 receptor antagonist
MPO myeloperoxidase
PRMT1 protein arginine methyltransferase 1
PTN pleiotrophin
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
S100A7 S100 calcium binding protein A7
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
TBCB tubulin folding cofactor B