BRD-A73605923_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

82 genes differentially expressed following the BRD-A73605923_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACSL1 acyl-CoA synthetase long-chain family member 1
ADD3 adducin 3 (gamma)
ARMCX2 armadillo repeat containing, X-linked 2
CAST calpastatin
CRIP1 cysteine-rich protein 1 (intestinal)
CSRP2 cysteine and glycine-rich protein 2
CXCL14 chemokine (C-X-C motif) ligand 14
CYB5A cytochrome b5 type A (microsomal)
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DCN decorin
DEFB1 defensin, beta 1
DHCR7 7-dehydrocholesterol reductase
DPYSL3 dihydropyrimidinase-like 3
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
FABP6 fatty acid binding protein 6, ileal
FLRT3 fibronectin leucine rich transmembrane protein 3
GSTA1 glutathione S-transferase alpha 1
GSTP1 glutathione S-transferase pi 1
GULP1 GULP, engulfment adaptor PTB domain containing 1
HEBP2 heme binding protein 2
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HOXA5 homeobox A5
IFI27 interferon, alpha-inducible protein 27
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
LDLR low density lipoprotein receptor
MAOB monoamine oxidase B
MID1IP1 MID1 interacting protein 1
MSMO1 methylsterol monooxygenase 1
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NES nestin
PALLD palladin, cytoskeletal associated protein
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1
RAB38 RAB38, member RAS oncogene family
RGCC regulator of cell cycle
RGS5 regulator of G-protein signaling 5
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
RND3 Rho family GTPase 3
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SCGB1D2 secretoglobin, family 1D, member 2
SEPP1 selenoprotein P, plasma, 1
TAGLN transgelin
THBS1 thrombospondin 1
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TLR4 toll-like receptor 4
TMSB15A thymosin beta 15a
TRIM22 tripartite motif containing 22
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
VAT1 vesicle amine transport 1

decreased expression

Symbol Name
AXL AXL receptor tyrosine kinase
BASP1 brain abundant, membrane attached signal protein 1
CCL5 chemokine (C-C motif) ligand 5
CDC42 cell division cycle 42
COL5A2 collagen, type V, alpha 2
COL6A3 collagen, type VI, alpha 3
DHRS2 dehydrogenase/reductase (SDR family) member 2
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
FOLR1 folate receptor 1 (adult)
HIPK1 homeodomain interacting protein kinase 1
HP haptoglobin
HS2ST1 heparan sulfate 2-O-sulfotransferase 1
IGFBP1 insulin-like growth factor binding protein 1
IKZF1 IKAROS family zinc finger 1 (Ikaros)
ITM2A integral membrane protein 2A
KYNU kynureninase
LOXL2 lysyl oxidase-like 2
MET MET proto-oncogene, receptor tyrosine kinase
NR2F1 nuclear receptor subfamily 2, group F, member 1
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
PKN2 protein kinase N2
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PLAU plasminogen activator, urokinase
PRKACB protein kinase, cAMP-dependent, catalytic, beta
RAB26 RAB26, member RAS oncogene family
RNF167 ring finger protein 167
SCG5 secretogranin V
SIK1 salt-inducible kinase 1
SOX9 SRY (sex determining region Y)-box 9
STX1A syntaxin 1A (brain)
TCAF1 TRPM8 channel-associated factor 1
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)