Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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46 genes differentially expressed following the BRD-A73741725_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
AKR1C3 | aldo-keto reductase family 1, member C3 |
AUTS2 | autism susceptibility candidate 2 |
CA12 | carbonic anhydrase XII |
CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) |
CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) |
CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) |
CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 |
DUSP1 | dual specificity phosphatase 1 |
EFEMP1 | EGF containing fibulin-like extracellular matrix protein 1 |
EFNA1 | ephrin-A1 |
GCLM | glutamate-cysteine ligase, modifier subunit |
GULP1 | GULP, engulfment adaptor PTB domain containing 1 |
HMOX1 | heme oxygenase 1 |
HSPA1A | heat shock 70kDa protein 1A |
HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein |
IGL | immunoglobulin lambda locus |
ME1 | malic enzyme 1, NADP(+)-dependent, cytosolic |
MTUS1 | microtubule associated tumor suppressor 1 |
NQO1 | NAD(P)H dehydrogenase, quinone 1 |
ODC1 | ornithine decarboxylase 1 |
PIR | pirin (iron-binding nuclear protein) |
S100P | S100 calcium binding protein P |
SQSTM1 | sequestosome 1 |
TBL1X | transducin (beta)-like 1X-linked |
TKT | transketolase |
TXNRD1 | thioredoxin reductase 1 |
Symbol | Name |
---|---|
DEFB1 | defensin, beta 1 |
DPT | dermatopontin |
EMP1 | epithelial membrane protein 1 |
ETNK1 | ethanolamine kinase 1 |
FABP7 | fatty acid binding protein 7, brain |
KMO | kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) |
KRAS | Kirsten rat sarcoma viral oncogene homolog |
LDLR | low density lipoprotein receptor |
MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
PLEKHA5 | pleckstrin homology domain containing, family A member 5 |
PTGDS | prostaglandin D2 synthase 21kDa (brain) |
PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
S100A6 | S100 calcium binding protein A6 |
SLAMF7 | SLAM family member 7 |
SPARCL1 | SPARC-like 1 (hevin) |
SPRED2 | sprouty-related, EVH1 domain containing 2 |
TFF3 | trefoil factor 3 (intestinal) |
WBP5 | WW domain binding protein 5 |