BRD-A76528577_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

43 genes differentially expressed following the BRD-A76528577_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADRB2 adrenoceptor beta 2, surface
ATF3 activating transcription factor 3
BIRC2 baculoviral IAP repeat containing 2
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CHIC2 cysteine-rich hydrophobic domain 2
CXCL8 chemokine (C-X-C motif) ligand 8
DHRS9 dehydrogenase/reductase (SDR family) member 9
DUSP10 dual specificity phosphatase 10
F3 coagulation factor III (thromboplastin, tissue factor)
FAM60A family with sequence similarity 60, member A
FHL2 four and a half LIM domains 2
GADD45B growth arrest and DNA-damage-inducible, beta
GPRC5A G protein-coupled receptor, class C, group 5, member A
IGFBP3 insulin-like growth factor binding protein 3
JUN jun proto-oncogene
KLF4 Kruppel-like factor 4 (gut)
KLF6 Kruppel-like factor 6
LAMB3 laminin, beta 3
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MGLL monoglyceride lipase
MMP10 matrix metallopeptidase 10
MYC v-myc avian myelocytomatosis viral oncogene homolog
PDGFA platelet-derived growth factor alpha polypeptide
PLAT plasminogen activator, tissue
PPP1R15A protein phosphatase 1, regulatory subunit 15A
RBP1 retinol binding protein 1, cellular
RGS2 regulator of G-protein signaling 2
RGS4 regulator of G-protein signaling 4
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
SAMD4A sterile alpha motif domain containing 4A
SCG5 secretogranin V
SIK1 salt-inducible kinase 1
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
SLPI secretory leukocyte peptidase inhibitor
TFPI2 tissue factor pathway inhibitor 2
TGFB2 transforming growth factor, beta 2
WT1 Wilms tumor 1

decreased expression

Symbol Name
CCL5 chemokine (C-C motif) ligand 5
CCNE2 cyclin E2
CPD carboxypeptidase D
DDIT4 DNA-damage-inducible transcript 4
HSPA1A heat shock 70kDa protein 1A