| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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121 genes differentially expressed following the BRD-A76528577_Vincristine sulfate_HCC515_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| AQP3 | aquaporin 3 (Gill blood group) |
| ARHGAP29 | Rho GTPase activating protein 29 |
| BHLHE41 | basic helix-loop-helix family, member e41 |
| CAB39 | calcium binding protein 39 |
| CALML5 | calmodulin-like 5 |
| CAPN2 | calpain 2, (m/II) large subunit |
| CAV1 | caveolin 1, caveolae protein, 22kDa |
| CD14 | CD14 molecule |
| CD9 | CD9 molecule |
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) |
| CNPY3 | canopy FGF signaling regulator 3 |
| CPM | carboxypeptidase M |
| CST1 | cystatin SN |
| CYFIP1 | cytoplasmic FMR1 interacting protein 1 |
| DMD | dystrophin |
| DMXL2 | Dmx-like 2 |
| DNAJC6 | DnaJ (Hsp40) homolog, subfamily C, member 6 |
| DST | dystonin |
| EFNB2 | ephrin-B2 |
| EMP1 | epithelial membrane protein 1 |
| EPCAM | epithelial cell adhesion molecule |
| FXYD3 | FXYD domain containing ion transport regulator 3 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide |
| HES1 | hes family bHLH transcription factor 1 |
| HIST1H1C | histone cluster 1, H1c |
| HIST1H2BC | histone cluster 1, H2bc |
| IPO13 | importin 13 |
| ITGA6 | integrin, alpha 6 |
| KIF1BP | KIF1 binding protein |
| KIF20A | kinesin family member 20A |
| LPAR1 | lysophosphatidic acid receptor 1 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 |
| LYN | LYN proto-oncogene, Src family tyrosine kinase |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MAOA | monoamine oxidase A |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 |
| NAT1 | N-acetyltransferase 1 (arylamine N-acetyltransferase) |
| NPY1R | neuropeptide Y receptor Y1 |
| PEX11A | peroxisomal biogenesis factor 11 alpha |
| PRUNE2 | prune homolog 2 (Drosophila) |
| PSD3 | pleckstrin and Sec7 domain containing 3 |
| PTGS1 | prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) |
| RAB9A | RAB9A, member RAS oncogene family |
| S100A11 | S100 calcium binding protein A11 |
| SGK1 | serum/glucocorticoid regulated kinase 1 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 |
| SLC1A1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 |
| SPAG1 | sperm associated antigen 1 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) |
| SSFA2 | sperm specific antigen 2 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) |
| STS | steroid sulfatase (microsomal), isozyme S |
| STX1A | syntaxin 1A (brain) |
| SYBU | syntabulin (syntaxin-interacting) |
| TACSTD2 | tumor-associated calcium signal transducer 2 |
| TTLL7 | tubulin tyrosine ligase-like family member 7 |
| UNC13B | unc-13 homolog B (C. elegans) |
| YWHAH | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta |
| Symbol | Name |
|---|---|
| AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) |
| AKR1C3 | aldo-keto reductase family 1, member C3 |
| ALB | albumin |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 |
| APOB | apolipoprotein B |
| ASPN | asporin |
| BCL2L1 | BCL2-like 1 |
| BID | BH3 interacting domain death agonist |
| BZW2 | basic leucine zipper and W2 domains 2 |
| C6ORF62 | chromosome 6 open reading frame 62 |
| CD200 | CD200 molecule |
| CD24 | CD24 molecule |
| CD36 | CD36 molecule (thrombospondin receptor) |
| CDK1 | cyclin-dependent kinase 1 |
| CHMP4A | charged multivesicular body protein 4A |
| CLNS1A | chloride channel, nucleotide-sensitive, 1A |
| CLU | clusterin |
| COL1A1 | collagen, type I, alpha 1 |
| CPE | carboxypeptidase E |
| CREB1 | cAMP responsive element binding protein 1 |
| DCN | decorin |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 |
| DICER1 | dicer 1, ribonuclease type III |
| E2F2 | E2F transcription factor 2 |
| EIF4B | eukaryotic translation initiation factor 4B |
| EIF5A | eukaryotic translation initiation factor 5A |
| FABP4 | fatty acid binding protein 4, adipocyte |
| GCH1 | GTP cyclohydrolase 1 |
| GPX3 | glutathione peroxidase 3 |
| GSTT1 | glutathione S-transferase theta 1 |
| HP | haptoglobin |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa |
| LRRC16A | leucine rich repeat containing 16A |
| LRRC17 | leucine rich repeat containing 17 |
| MARCH6 | membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
| ORM1 | orosomucoid 1 |
| PAK1 | p21 protein (Cdc42/Rac)-activated kinase 1 |
| PEG3 | paternally expressed 3 |
| PHGDH | phosphoglycerate dehydrogenase |
| PRDX2 | peroxiredoxin 2 |
| RARRES2 | retinoic acid receptor responder (tazarotene induced) 2 |
| RBP4 | retinol binding protein 4, plasma |
| RPS11 | ribosomal protein S11 |
| SLC16A7 | solute carrier family 16 (monocarboxylate transporter), member 7 |
| SLC38A1 | solute carrier family 38, member 1 |
| SMAD1 | SMAD family member 1 |
| SRSF7 | serine/arginine-rich splicing factor 7 |
| SST | somatostatin |
| SULF1 | sulfatase 1 |
| SUPV3L1 | suppressor of var1, 3-like 1 (S. cerevisiae) |
| TRAK2 | trafficking protein, kinesin binding 2 |
| TTPAL | tocopherol (alpha) transfer protein-like |
| TTR | transthyretin |
| TYMS | thymidylate synthetase |
| VCAN | versican |
| ZFP36L2 | ZFP36 ring finger protein-like 2 |
| ZNF24 | zinc finger protein 24 |
